 Interleukin-1beta
"Interleukin-1beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
| Descriptor ID |
D053583
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| MeSH Number(s) |
D12.644.276.374.465.501.600 D12.644.276.374.500.400.600 D12.776.467.374.465.501.600 D12.776.467.374.500.400.600 D23.529.374.465.501.600 D23.529.374.500.400.600
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| Concept/Terms |
Interleukin-1beta- Interleukin-1beta
- Interleukin 1beta
- Interleukin-1 beta
- Interleukin 1 beta
- Catabolin
- IL-1 beta
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1beta".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1beta".
This graph shows the total number of publications written about "Interleukin-1beta" by people in UAMS Profiles by year, and whether "Interleukin-1beta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2020 | 3 | 2 | 5 | | 2019 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2016 | 0 | 4 | 4 | | 2015 | 2 | 2 | 4 | | 2014 | 4 | 3 | 7 | | 2013 | 1 | 2 | 3 | | 2012 | 0 | 4 | 4 | | 2011 | 1 | 2 | 3 | | 2010 | 1 | 2 | 3 | | 2009 | 3 | 2 | 5 | | 2008 | 0 | 2 | 2 | | 2007 | 2 | 1 | 3 | | 2006 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-1beta" by people in Profiles over the past ten years.
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Qu Y, Qiu L, Qiu H, Shen Y, Tang M, Huang Y, Peng Y, Wang J, Fu Q. Notopterol alleviates the progression of osteoarthritis: An in vitro and in vivo study. Cytokine. 2023 09; 169:156309.
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Qu Y, Shen Y, Teng L, Huang Y, Yang Y, Jian X, Fan S, Wu P, Fu Q. Chicoric acid attenuates tumor necrosis factor-a-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-?B signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model. Int Immunopharmacol. 2022 Oct; 111:109129.
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Kore RA, Wang X, Henson JC, Ding Z, Jamshidi-Parsian A, Mehta JL. Proteomic basis of modulation of postischemic fibrosis by MSC exosomes. Am J Physiol Regul Integr Comp Physiol. 2021 11 01; 321(5):R639-R654.
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Wang G, Sweren E, Liu H, Wier E, Alphonse MP, Chen R, Islam N, Li A, Xue Y, Chen J, Park S, Chen Y, Lee S, Wang Y, Wang S, Archer NK, Andrews W, Kane MA, Dare E, Reddy SK, Hu Z, Grice EA, Miller LS, Garza LA. Bacteria induce skin regeneration via IL-1? signaling. Cell Host Microbe. 2021 05 12; 29(5):777-791.e6.
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Li X, Brickell AN, Wang X, Zhou S, Ding Z. NADPH oxidase promotes PCSK9 secretion in macrophages. J Mol Cell Cardiol. 2021 04; 153:42-43.
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Gyorke CE, Kollipara A, Allen J, Zhang Y, Ezzell JA, Darville T, Montgomery SA, Nagarajan UM. IL-1a Is Essential for Oviduct Pathology during Genital Chlamydial Infection in Mice. J Immunol. 2020 12 01; 205(11):3037-3049.
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Kovacs SB, Oh C, Maltez VI, McGlaughon BD, Verma A, Miao EA, Aachoui Y. Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium. Cell Rep. 2020 07 28; 32(4):107967.
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Ding Z, Wang X, Liu S, Zhou S, Kore RA, Mu S, Deng X, Fan Y, Mehta JL. NLRP3 inflammasome via IL-1? regulates PCSK9 secretion. Theranostics. 2020; 10(16):7100-7110.
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Alkhuriji AF, Al Omar SY, Babay ZA, El-Khadragy MF, Mansour LA, Alharbi WG, Khalil MI. Association of IL-1?, IL-6, TNF-a, and TGF?1 Gene Polymorphisms with Recurrent Spontaneous Abortion in Polycystic Ovary Syndrome. Dis Markers. 2020; 2020:6076274.
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Balasubramaniam M, Parcon PA, Bose C, Liu L, Jones RA, Farlow MR, Mrak RE, Barger SW, Griffin WST. Interleukin-1? drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site. J Neuroinflammation. 2019 Dec 27; 16(1):275.
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Chen J, Del Valle L, Lin HY, Plaisance-Bonstaff K, Forrest JC, Post SR, Qin Z. Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation. Virology. 2019 10; 536:16-19.
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Nagarajan UM, Tripathy M, Kollipara A, Allen J, Goodwin A, Whittimore J, Wyrick PB, Rank RG. Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp. Immunol Cell Biol. 2018 03; 96(3):246-256.
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Fouda AM, Youssef AR, Sharaf Eldin O. Comparative study of amlodipine vs. cilnidipine for the prevention of hepatic ischemia-reperfusion injury in rat model. Fundam Clin Pharmacol. 2018 Apr; 32(2):163-173.
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Hirashima R, Itoh T, Tukey RH, Fujiwara R. Prediction of drug-induced liver injury using keratinocytes. J Appl Toxicol. 2017 07; 37(7):863-872.
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Farris RA, Price ET. Reverse Translational Study of Fenofibrate's Observed Effects in Diabetes-Associated Retinopathy. Clin Transl Sci. 2017 03; 10(2):110-116.
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Chen X, Chen X, Xu Y, Yang W, Wu N, Ye H, Yang JY, Hong Q, Xin Y, Yang MQ, Deng Y, Duan S. Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease. Hum Genomics. 2016 07 25; 10 Suppl 2:21.
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Liu M, Chen S, Yueh MF, Fujiwara R, Konopnicki C, Hao H, Tukey RH. Cadmium and arsenic override NF-?B developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia. Biochem Pharmacol. 2016 06 15; 110-111:37-46.
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Liu Y, Almeida M, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice. Am J Physiol Endocrinol Metab. 2016 May 01; 310(9):E762-73.
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Finethy R, Jorgensen I, Haldar AK, de Zoete MR, Strowig T, Flavell RA, Yamamoto M, Nagarajan UM, Miao EA, Coers J. Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. Infect Immun. 2015 Dec; 83(12):4740-9.
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Cieniewicz B, Dong Q, Li G, Forrest JC, Mounce BC, Tarakanova VL, van der Velden A, Krug LT. Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1? Production upon Extrinsic Stimulation in Culture. J Virol. 2015 Jul; 89(13):6562-74.
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Sivaraman V, Pechous RD, Stasulli NM, Eichelberger KR, Miao EA, Goldman WE. Yersinia pestis activates both IL-1? and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. PLoS Pathog. 2015 Mar; 11(3):e1004688.
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Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, Yin H, Zahniser NR, Katz JL, Rice KC, Maier SF, Bachtell RK, Watkins LR. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Mol Psychiatry. 2015 Dec; 20(12):1525-37.
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Wang X, Khaidakov M, Guo Z, Ding Z, He Q, Mehta JL. LOX-1 deletion limits cardiac angiogenesis in mice given angiotensin II. Cardiovasc Drugs Ther. 2014 Oct; 28(5):441-6.
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Dai Y, Dai D, Wang X, Ding Z, Mehta JL. DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway. Cardiovasc Drugs Ther. 2014 Oct; 28(5):425-32.
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Kore RA, Abraham EC. Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Biochem Biophys Res Commun. 2014 Oct 24; 453(3):326-31.
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Pesek R, Fox R. Successful treatment of Schnitzler syndrome with canakinumab. Cutis. 2014 Sep; 94(3):E11-2.
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Sullivan CB, Porter RM, Evans CH, Ritter T, Shaw G, Barry F, Murphy JM. TNFa and IL-1? influence the differentiation and migration of murine MSCs independently of the NF-?B pathway. Stem Cell Res Ther. 2014 Aug 27; 5(4):104.
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Ding Z, Liu S, Wang X, Theus S, Fan Y, Deng X, Mehta JL. LOX-1 - dependent mitochondrial DNA damage and NLRP3 activation during systemic inflammation in mice. Biochem Biophys Res Commun. 2014 Sep 05; 451(4):637-43.
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Gopal R, Monin L, Slight S, Uche U, Blanchard E, Fallert Junecko BA, Ramos-Payan R, Stallings CL, Reinhart TA, Kolls JK, Kaushal D, Nagarajan U, Rangel-Moreno J, Khader SA. Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection. PLoS Pathog. 2014 May; 10(5):e1004099.
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Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, Tall AR, Goldberg IJ, Murphy AJ. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metab. 2014 May 06; 19(5):821-35.
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Trickler WJ, Lantz-McPeak SM, Robinson BL, Paule MG, Slikker W, Biris AS, Schlager JJ, Hussain SM, Kanungo J, Gonzalez C, Ali SF. Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles. Drug Metab Rev. 2014 May; 46(2):224-31.
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