Telomerase
"Telomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
Descriptor ID |
D019098
|
MeSH Number(s) |
D08.811.913.696.445.308.300.750.750 D12.776.157.725.500.921 D12.776.664.962.500.921
|
Concept/Terms |
Telomerase- Telomerase
- Telomerase Reverse Transcriptase
- Reverse Transcriptase, Telomerase
- Transcriptase, Telomerase Reverse
Telomerase Catalytic Subunit- Telomerase Catalytic Subunit
- Catalytic Subunit, Telomerase
- Subunit, Telomerase Catalytic
- Telomerase Reverse Transcriptase Catalytic Subunit
|
Below are MeSH descriptors whose meaning is more general than "Telomerase".
Below are MeSH descriptors whose meaning is more specific than "Telomerase".
This graph shows the total number of publications written about "Telomerase" by people in UAMS Profiles by year, and whether "Telomerase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
---|
2021 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 | 2017 | 2 | 0 | 2 | 2016 | 0 | 3 | 3 | 2013 | 2 | 0 | 2 | 2011 | 1 | 0 | 1 | 2010 | 1 | 1 | 2 | 2008 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2004 | 2 | 0 | 2 | 2003 | 1 | 2 | 3 | 2002 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 | 1999 | 2 | 0 | 2 | 1996 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Telomerase" by people in Profiles over the past ten years.
-
Sadhukhan R, Ghosh U. PARP1 modulates telomere sister chromatid exchange and telomere length homeostasis by regulating telomere localization of SLX4 in U2OS cells. Life Sci. 2021 Jul 15; 277:119556.
-
Mannan R, Taylor AS, Spratt DE, Chinnaiyan AM, Montgomery JS, Brown NA, Mehra R. TERT- beyond the territory: Usage of PCR-based TERT promoter assay in defining urothelial carcinoma in a case of long-standing prostatic adenocarcinoma. Pathol Res Pract. 2020 Jan; 216(1):152663.
-
Brown NA, Lew M, Weigelin HC, Weizer AZ, Montgomery JS, Betz BL, Mehra R. Comparative study of TERT promoter mutation status within spatially, temporally and morphologically distinct components of urothelial carcinoma. Histopathology. 2018 01; 72(2):354-356.
-
Balasubramaniam M, Reis RJS, Ayyadevara S, Wang X, Ganne A, Khaidakov M. Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase. Mech Ageing Dev. 2017 09; 166:55-63.
-
Zhao S, Bellone S, Lopez S, Thakral D, Schwab C, English DP, Black J, Cocco E, Choi J, Zammataro L, Predolini F, Bonazzoli E, Bi M, Buza N, Hui P, Wong S, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Odicino F, Pecorelli S, Donzelli C, Ardighieri L, Facchetti F, Falchetti M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Mane S, Angioli R, Terranova C, Quick CM, Edraki B, Bilgüvar K, Lee M, Choi M, Stiegler AL, Boggon TJ, Schlessinger J, Lifton RP, Santin AD. Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):12238-12243.
-
Choudhury SR, Cui Y, Narayanan A, Gilley DP, Huda N, Lo CL, Zhou FC, Yernool D, Irudayaraj J. Optogenetic regulation of site-specific subtelomeric DNA methylation. Oncotarget. 2016 Aug 02; 7(31):50380-50391.
-
Wayhelova M, Mikulasova A, Smetana J, Vallova V, Blazkova D, Filkova H, Moukova L, Kuglik P. Detection of oncogenic mutations in cervical carcinoma using method High Resolution Melting (HRM). Neoplasma. 2016; 63(5):779-88.
-
Lee JH, Jeong SA, Khadka P, Hong J, Chung IK. Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles. Nucleic Acids Res. 2015 Sep 30; 43(17):8435-51.
-
Jeong SA, Kim K, Lee JH, Cha JS, Khadka P, Cho HS, Chung IK. Akt-mediated phosphorylation increases the binding affinity of hTERT for importin a to promote nuclear translocation. J Cell Sci. 2015 Jun 15; 128(12):2287-301.
-
Sinha S, Shukla S, Khan S, Farhan M, Kamal MA, Meeran SM. Telomeric Repeat Containing RNA (TERRA): Aging and Cancer. CNS Neurol Disord Drug Targets. 2015; 14(7):936-46.
-
Khadka P, Lee JH, Baek SH, Oh SY, Chung IK. DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres. Biochem J. 2014 Oct 01; 463(1):19-30.
-
Popuri V, Hsu J, Khadka P, Horvath K, Liu Y, Croteau DL, Bohr VA. Human RECQL1 participates in telomere maintenance. Nucleic Acids Res. 2014 May; 42(9):5671-88.
-
Lee JH, Lee YS, Jeong SA, Khadka P, Roth J, Chung IK. Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase. Histochem Cell Biol. 2014 Feb; 141(2):137-52.
-
Remke M, Ramaswamy V, Peacock J, Shih DJ, Koelsche C, Northcott PA, Hill N, Cavalli FM, Kool M, Wang X, Mack SC, Barszczyk M, Morrissy AS, Wu X, Agnihotri S, Luu B, Jones DT, Garzia L, Dubuc AM, Zhukova N, Vanner R, Kros JM, French PJ, Van Meir EG, Vibhakar R, Zitterbart K, Chan JA, Bognár L, Klekner A, Lach B, Jung S, Saad AG, Liau LM, Albrecht S, Zollo M, Cooper MK, Thompson RC, Delattre OO, Bourdeaut F, Doz FF, Garami M, Hauser P, Carlotti CG, Van Meter TE, Massimi L, Fults D, Pomeroy SL, Kumabe T, Ra YS, Leonard JR, Elbabaa SK, Mora J, Rubin JB, Cho YJ, McLendon RE, Bigner DD, Eberhart CG, Fouladi M, Wechsler-Reya RJ, Faria CC, Croul SE, Huang A, Bouffet E, Hawkins CE, Dirks PB, Weiss WA, Schüller U, Pollack IF, Rutkowski S, Meyronet D, Jouvet A, Fèvre-Montange M, Jabado N, Perek-Polnik M, Grajkowska WA, Kim SK, Rutka JT, Malkin D, Tabori U, Pfister SM, Korshunov A, von Deimling A, Taylor MD. TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathol. 2013 Dec; 126(6):917-29.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|