Protein Tyrosine Phosphatase, Non-Receptor Type 1
"Protein Tyrosine Phosphatase, Non-Receptor Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Descriptor ID |
D054562
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MeSH Number(s) |
D08.811.277.352.650.775.300.100 D12.644.360.585.100 D12.776.476.564.100
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Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 1- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Protein Tyrosine Phosphatase, Non Receptor Type 1
- PTPase HA2
- PTPase 1B
- Protein Tyrosine Phosphatase 1B
- Protein-Tyrosine Phosphatase HA2
- Protein Tyrosine Phosphatase HA2
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Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in UAMS Profiles by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in Profiles over the past ten years.
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Mobasher MA, de Toro-Mart?n J, Gonz?lez-Rodr?guez ?, Ramos S, Letzig LG, James LP, Muntan? J, ?lvarez C, Valverde ?M. Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes. J Biol Chem. 2014 Oct 17; 289(42):29406-19.
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Lopes PC, Fuhrmann A, Carvalho F, Sereno J, Santos MR, Pereira MJ, Eriksson JW, Reis F, Carvalho E. Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment. Biochem Pharmacol. 2014 Sep 01; 91(1):61-73.
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