 HSP70 Heat-Shock Proteins
"HSP70 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of MOLECULAR CHAPERONES found in both prokaryotes and in several compartments of eukaryotic cells. These proteins can interact with polypeptides during a variety of assembly processes in such a way as to prevent the formation of nonfunctional structures.
| Descriptor ID |
D018840
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| MeSH Number(s) |
D12.776.580.216.375
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| Concept/Terms |
HSP70 Heat-Shock Proteins- HSP70 Heat-Shock Proteins
- HSP70 Heat Shock Proteins
- Heat-Shock Proteins, HSP70
- Heat-Shock Protein 70
- Heat Shock Protein 70
- Heat-Shock Proteins 70
- Heat Shock Proteins 70
- Heat Shock 70 kDa Protein
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Below are MeSH descriptors whose meaning is more general than "HSP70 Heat-Shock Proteins".
Below are MeSH descriptors whose meaning is more specific than "HSP70 Heat-Shock Proteins".
This graph shows the total number of publications written about "HSP70 Heat-Shock Proteins" by people in UAMS Profiles by year, and whether "HSP70 Heat-Shock Proteins" was a major or minor topic of these publication.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2014 | 1 | 1 | 2 | | 2013 | 4 | 3 | 7 | | 2012 | 1 | 2 | 3 | | 2011 | 0 | 2 | 2 | | 2010 | 2 | 1 | 3 | | 2009 | 4 | 1 | 5 | | 2008 | 1 | 0 | 1 | | 2007 | 2 | 1 | 3 | | 2006 | 3 | 1 | 4 | | 2005 | 0 | 1 | 1 | | 2004 | 2 | 2 | 4 | | 2003 | 0 | 1 | 1 | | 2001 | 3 | 0 | 3 | | 2000 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 1998 | 2 | 1 | 3 | | 1997 | 1 | 1 | 2 | | 1996 | 1 | 1 | 2 | | 1995 | 2 | 0 | 2 |
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Below are the most recent publications written about "HSP70 Heat-Shock Proteins" by people in Profiles over the past ten years.
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Zuhl M, Dokladny K, Mermier C, Schneider S, Salgado R, Moseley P. The effects of acute oral glutamine supplementation on exercise-induced gastrointestinal permeability and heat shock protein expression in peripheral blood mononuclear cells. Cell Stress Chaperones. 2015 Jan; 20(1):85-93.
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Zhang L, Fok JH, Davies FE. Heat shock proteins in multiple myeloma. Oncotarget. 2014 Mar 15; 5(5):1132-48.
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Zuhl MN, Lanphere KR, Kravitz L, Mermier CM, Schneider S, Dokladny K, Moseley PL. Effects of oral glutamine supplementation on exercise-induced gastrointestinal permeability and tight junction protein expression. J Appl Physiol (1985). 2014 Jan 15; 116(2):183-91.
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de Matos MA, Ottone Vde O, Duarte TC, Sampaio PF, Costa KB, Fonseca CA, Neves MP, Schneider SM, Moseley P, Coimbra CC, Magalhães Fde C, Rocha-Vieira E, Amorim FT. Exercise reduces cellular stress related to skeletal muscle insulin resistance. Cell Stress Chaperones. 2014 Mar; 19(2):263-70.
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Zhang L, Fok JJ, Mirabella F, Aronson LI, Fryer RA, Workman P, Morgan GJ, Davies FE. Hsp70 inhibition induces myeloma cell death via the intracellular accumulation of immunoglobulin and the generation of proteotoxic stress. Cancer Lett. 2013 Oct 01; 339(1):49-59.
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Nowak G, Soundararajan S, Mestril R. Protein kinase C-a interaction with iHSP70 in mitochondria promotes recovery of mitochondrial function after injury in renal proximal tubular cells. Am J Physiol Renal Physiol. 2013 Sep 01; 305(5):F764-76.
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Dokladny K, Zuhl MN, Mandell M, Bhattacharya D, Schneider S, Deretic V, Moseley PL. Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. J Biol Chem. 2013 May 24; 288(21):14959-72.
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Hodeify R, Megyesi J, Tarcsafalvi A, Mustafa HI, Hti Lar Seng NS, Price PM. Gender differences control the susceptibility to ER stress-induced acute kidney injury. Am J Physiol Renal Physiol. 2013 Apr 01; 304(7):F875-82.
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Dutta A, Girotra M, Merchant N, Nair P, Dutta SK. Evidence of multimeric forms of HSP70 with phosphorylation on serine and tyrosine residues--implications for roles of HSP70 in detection of GI cancers. Asian Pac J Cancer Prev. 2013; 14(10):5741-5.
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Zhang L, Davies F. As stressful as learning your ABC. Leuk Res. 2013 Jan; 37(1):1-2.
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Dutta SK, Girotra M, Singla M, Dutta A, Otis Stephen F, Nair PP, Merchant NB. Serum HSP70: a novel biomarker for early detection of pancreatic cancer. Pancreas. 2012 May; 41(4):530-4.
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Dutta SK, Agrawal K, Girotra M, Fleisher AS, Motevalli M, Mah'moud MA, Nair PP. Barrett's esophagus and ß-carotene therapy: symptomatic improvement in GERD and enhanced HSP70 expression in esophageal mucosa. Asian Pac J Cancer Prev. 2012; 13(12):6011-6.
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Tusi SK, Khalaj L, Ashabi G, Kiaei M, Khodagholi F. Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress. Biomaterials. 2011 Aug; 32(23):5438-58.
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Hadley KC, Borrelli MJ, Lepock JR, McLaurin J, Croul SE, Guha A, Chakrabartty A. Multiphoton ANS fluorescence microscopy as an in vivo sensor for protein misfolding stress. Cell Stress Chaperones. 2011 Sep; 16(5):549-61.
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Antonoff MB, Chugh R, Skube SJ, Dudeja V, Borja-Cacho D, Clawson KA, Vickers SM, Saluja AK. Role of Hsp-70 in triptolide-mediated cell death of neuroblastoma. J Surg Res. 2010 Sep; 163(1):72-8.
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Lochhead JJ, McCaffrey G, Quigley CE, Finch J, DeMarco KM, Nametz N, Davis TP. Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation. J Cereb Blood Flow Metab. 2010 Sep; 30(9):1625-36.
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Todorova VK, Klimberg VS, Hennings L, Kieber-Emmons T, Pashov A. Immunomodulatory effects of radiofrequency ablation in a breast cancer model. Immunol Invest. 2010; 39(1):74-92.
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Song H, Moseley PL, Lowe SL, Ozbun MA. Inducible heat shock protein 70 enhances HPV31 viral genome replication and virion production during the differentiation-dependent life cycle in human keratinocytes. Virus Res. 2010 Jan; 147(1):113-22.
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Antonoff MB, Chugh R, Borja-Cacho D, Dudeja V, Clawson KA, Skube SJ, Sorenson BS, Saltzman DA, Vickers SM, Saluja AK. Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo. Surgery. 2009 Aug; 146(2):282-90.
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Moseley PL. Nitric oxide and the stress response--two 2-edged swords swung together. Exerc Sport Sci Rev. 2009 Apr; 37(2):57.
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Dudeja V, Mujumdar N, Phillips P, Chugh R, Borja-Cacho D, Dawra RK, Vickers SM, Saluja AK. Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms. Gastroenterology. 2009 May; 136(5):1772-82.
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Andreasen AS, Pedersen-Skovsgaard T, Mortensen OH, van Hall G, Moseley PL, Pedersen BK. The effect of glutamine infusion on the inflammatory response and HSP70 during human experimental endotoxaemia. Crit Care. 2009; 13(1):R7.
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Dokladny K, Wharton W, Ma TY, Moseley PL. Lack of cross-tolerance following heat and cadmium exposure in functional MDCK monolayers. J Appl Toxicol. 2008 Oct; 28(7):885-94.
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Sharma R, Sharma A, Dwivedi S, Zimniak P, Awasthi S, Awasthi YC. 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. Biochemistry. 2008 Jan 08; 47(1):143-56.
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Phillips PA, Dudeja V, McCarroll JA, Borja-Cacho D, Dawra RK, Grizzle WE, Vickers SM, Saluja AK. Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. Cancer Res. 2007 Oct 01; 67(19):9407-16.
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