 Metabolomics
"Metabolomics" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
| Descriptor ID |
D055432
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| MeSH Number(s) |
H01.158.201.586 H01.158.273.180.599 H01.181.122.638
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Metabolomics".
Below are MeSH descriptors whose meaning is more specific than "Metabolomics".
This graph shows the total number of publications written about "Metabolomics" by people in UAMS Profiles by year, and whether "Metabolomics" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 1 | 2 | | 2020 | 3 | 9 | 12 | | 2019 | 6 | 4 | 10 | | 2018 | 2 | 4 | 6 | | 2017 | 0 | 3 | 3 | | 2016 | 4 | 4 | 8 | | 2015 | 1 | 4 | 5 | | 2014 | 2 | 4 | 6 | | 2013 | 5 | 2 | 7 | | 2012 | 2 | 2 | 4 | | 2010 | 1 | 2 | 3 | | 2009 | 3 | 2 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Metabolomics" by people in Profiles over the past ten years.
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Margolis LM, Karl JP, Wilson MA, Coleman JL, Ferrando AA, Young AJ, Pasiakos SM. Metabolomic profiles are reflective of hypoxia-induced insulin resistance during exercise in healthy young adult males. Am J Physiol Regul Integr Comp Physiol. 2021 07 01; 321(1):R1-R11.
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Siebert JC, Saint-Cyr M, Borengasser SJ, Wagner BD, Lozupone CA, Görg C. CANTARE: finding and visualizing network-based multi-omic predictive models. BMC Bioinformatics. 2021 Feb 19; 22(1):80.
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Rosa F, Matazel KS, Bowlin AK, Williams KD, Elolimy AA, Adams SH, Bode L, Yeruva L. Neonatal Diet Impacts the Large Intestine Luminal Metabolome at Weaning and Post-Weaning in Piglets Fed Formula or Human Milk. Front Immunol. 2020; 11:607609.
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Rosa F, Mercer KE, Lin H, Sims CR, Pack LM, Goode G, Badger T, Andres A, Yeruva L. Early Infant Formula Feeding Impacts Urinary Metabolite Profile at 3 Months of Age. Nutrients. 2020 Nov 20; 12(11).
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Saben JL, Sims CR, Piccolo BD, Andres A. Maternal adiposity alters the human milk metabolome: associations between nonglucose monosaccharides and infant adiposity. Am J Clin Nutr. 2020 11 11; 112(5):1228-1239.
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Nayfach S, Roux S, Seshadri R, Udwary D, Varghese N, Schulz F, Wu D, Paez-Espino D, Chen IM, Huntemann M, Palaniappan K, Ladau J, Mukherjee S, Reddy TBK, Nielsen T, Kirton E, Faria JP, Edirisinghe JN, Henry CS, Jungbluth SP, Chivian D, Dehal P, Wood-Charlson EM, Arkin AP, Tringe SG, Visel A, Woyke T, Mouncey NJ, Ivanova NN, Kyrpides NC, Eloe-Fadrosh EA. A genomic catalog of Earth's microbiomes. Nat Biotechnol. 2021 04; 39(4):499-509.
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Evans AM, O'Donovan C, Playdon M, Beecher C, Beger RD, Bowden JA, Broadhurst D, Clish CB, Dasari S, Dunn WB, Griffin JL, Hartung T, Hsu PC, Huan T, Jans J, Jones CM, Kachman M, Kleensang A, Lewis MR, Monge ME, Mosley JD, Taylor E, Tayyari F, Theodoridis G, Torta F, Ubhi BK, Vuckovic D. Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners. Metabolomics. 2020 10 12; 16(10):113.
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Dienel GA. Metabolomic and Imaging Mass Spectrometric Assays of Labile Brain Metabolites: Critical Importance of Brain Harvest Procedures. Neurochem Res. 2020 Nov; 45(11):2586-2606.
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Kim JH, Lagojda A, Kuehne D, Tshitenge DT, Chaudhuri S, Walker DP, Head G. Determination of Cotton as a Larval Feeding Source for Lepidopteran Moths Using a Derivative from Cotton Metabolites as a Marker by LC-MS/MS Method. J Chem Ecol. 2020 Oct; 46(10):956-966.
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Nakamura N, Pence LM, Cao Z, Beger RD. Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones. Metabolomics. 2020 09 07; 16(9):95.
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Mercer KE, Yeruva L, Pack L, Graham JL, Stanhope KL, Chintapalli SV, Wankhade UD, Shankar K, Havel PJ, Adams SH, Piccolo BD. Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites. Am J Physiol Gastrointest Liver Physiol. 2020 08 01; 319(2):G157-G169.
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Unger K, Li Y, Yeh C, Barac A, Srichai MB, Ballew EA, Girgis M, Jayatilake M, Sridharan V, Boerma M, Cheema AK. Plasma metabolite biomarkers predictive of radiation induced cardiotoxicity. Radiother Oncol. 2020 11; 152:133-145.
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Engelen MPKJ, Jonker R, Thaden JJ, Ten Have GAM, Jeon MS, Dasarathy S, Deutz NEP. Comprehensive metabolic flux analysis to explain skeletal muscle weakness in COPD. Clin Nutr. 2020 10; 39(10):3056-3065.
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Reisdorph NA, Hendricks AE, Tang M, Doenges KA, Reisdorph RM, Tooker BC, Quinn K, Borengasser SJ, Nkrumah-Elie Y, Frank DN, Campbell WW, Krebs NF. Nutrimetabolomics reveals food-specific compounds in urine of adults consuming a DASH-style diet. Sci Rep. 2020 01 24; 10(1):1157.
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Du K, Chitneni SK, Suzuki A, Wang Y, Henao R, Hyun J, Premont RT, Naggie S, Moylan CA, Bashir MR, Abdelmalek MF, Diehl AM. Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression. Cell Mol Gastroenterol Hepatol. 2020; 10(1):1-21.
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Khoomrung S, Nookaew I, Sen P, Olafsdottir TA, Persson J, Moritz T, Andersen P, Harandi AM, Nielsen J. Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum. J Proteome Res. 2020 01 03; 19(1):269-278.
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Grapov D, Fiehn O, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Hoppel CL, Harper ME, Adams SH. Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: impact of a fitness and weight loss intervention. Am J Physiol Endocrinol Metab. 2019 12 01; 317(6):E999-E1014.
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Ilaiwy A, Ten Have GAM, Bain JR, Muehlbauer MJ, O'Neal SK, Berthiaume JM, Parry TL, Deutz NE, Willis MS. Identification of Metabolic Changes in Ileum, Jejunum, Skeletal Muscle, Liver, and Lung in a Continuous I.V. Pseudomonas aeruginosa Model of Sepsis Using Nontargeted Metabolomics Analysis. Am J Pathol. 2019 09; 189(9):1797-1813.
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Sun J, Beger RD, Sloper DT, Nakamura N. Metabolomics-based pathway changes in testis fragments treated with ethinylestradiol in vitro. Birth Defects Res. 2019 12 01; 111(20):1643-1654.
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Viant MR, Ebbels TMD, Beger RD, Ekman DR, Epps DJT, Kamp H, Leonards PEG, Loizou GD, MacRae JI, van Ravenzwaay B, Rocca-Serra P, Salek RM, Walk T, Weber RJM. Use cases, best practice and reporting standards for metabolomics in regulatory toxicology. Nat Commun. 2019 07 10; 10(1):3041.
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Bhattacharyya S, Ahmed AT, Arnold M, Liu D, Luo C, Zhu H, Mahmoudiandehkordi S, Neavin D, Louie G, Dunlop BW, Frye MA, Wang L, Weinshilboum RM, Krishnan RR, Rush AJ, Kaddurah-Daouk R. Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients. Transl Psychiatry. 2019 07 04; 9(1):173.
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Cao Z, Kamlage B, Wagner-Golbs A, Maisha M, Sun J, Schnackenberg LK, Pence L, Schmitt TC, Daniels JR, Rogstad S, Beger RD, Yu LR. An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma. J Proteome Res. 2019 06 07; 18(6):2411-2421.
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Matich EK, Chavez Soria NG, Aga DS, Atilla-Gokcumen GE. Applications of metabolomics in assessing ecological effects of emerging contaminants and pollutants on plants. J Hazard Mater. 2019 07 05; 373:527-535.
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Beger RD, Dunn WB, Bandukwala A, Bethan B, Broadhurst D, Clish CB, Dasari S, Derr L, Evans A, Fischer S, Flynn T, Hartung T, Herrington D, Higashi R, Hsu PC, Jones C, Kachman M, Karuso H, Kruppa G, Lippa K, Maruvada P, Mosley J, Ntai I, O'Donovan C, Playdon M, Raftery D, Shaughnessy D, Souza A, Spaeder T, Spalholz B, Tayyari F, Ubhi B, Verma M, Walk T, Wilson I, Witkin K, Bearden DW, Zanetti KA. Towards quality assurance and quality control in untargeted metabolomics studies. Metabolomics. 2019 01 03; 15(1):4.
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Davidson JA, Pfeifer Z, Frank B, Tong S, Urban TT, Wischmeyer PA, Mourani P, Landeck B, Christians U, Klawitter J. Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay. J Am Heart Assoc. 2018 12 18; 7(24):e010711.
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Lubet RA, Beger RD, Miller MS, Luster J, Seifried HE, Grubbs CJ. Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents. Cancer Prev Res (Phila). 2018 12; 11(12):831-840.
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Zhang J, Bhattacharyya S, Hickner RC, Light AR, Lambert CJ, Gale BK, Fiehn O, Adams SH. Skeletal muscle interstitial fluid metabolomics at rest and associated with an exercise bout: application in rats and humans. Am J Physiol Endocrinol Metab. 2019 01 01; 316(1):E43-E53.
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Piccolo BD, Graham JL, Stanhope KL, Nookaew I, Mercer KE, Chintapalli SV, Wankhade UD, Shankar K, Havel PJ, Adams SH. Diabetes-associated alterations in the cecal microbiome and metabolome are independent of diet or environment in the UC Davis Type 2 Diabetes Mellitus Rat model. Am J Physiol Endocrinol Metab. 2018 11 01; 315(5):E961-E972.
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Koturbash I. 2017 Michael Fry Award Lecture When DNA is Actually Not a Target: Radiation Epigenetics as a Tool to Understand and Control Cellular Response to Ionizing Radiation. Radiat Res. 2018 07; 190(1):5-11.
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Fujiwara R, Haag M, Schaeffeler E, Nies AT, Zanger UM, Schwab M. Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia. Hepatology. 2018 04; 67(4):1609-1619.
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Morris JK, Piccolo BD, Shankar K, Thyfault JP, Adams SH. The serum metabolomics signature of type 2 diabetes is obscured in Alzheimer's disease. Am J Physiol Endocrinol Metab. 2018 06 01; 314(6):E584-E596.
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Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K, Szabo C, Chao C, Hellmich MR. Upregulation of Cystathionine-ß-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis. Cancer Res. 2017 11 01; 77(21):5741-5754.
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Ramaker RC, Bowling KM, Lasseigne BN, Hagenauer MH, Hardigan AA, Davis NS, Gertz J, Cartagena PM, Walsh DM, Vawter MP, Jones EG, Schatzberg AF, Barchas JD, Watson SJ, Bunney BG, Akil H, Bunney WE, Li JZ, Cooper SJ, Myers RM. Post-mortem molecular profiling of three psychiatric disorders. Genome Med. 2017 07 28; 9(1):72.
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Aguer C, Piccolo BD, Fiehn O, Adams SH, Harper ME. A novel amino acid and metabolomics signature in mice overexpressing muscle uncoupling protein 3. FASEB J. 2017 02; 31(2):814-827.
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Baker L, Lanz B, Andreola F, Ampuero J, Wijeyesekera A, Holmes E, Deutz N. New technologies - new insights into the pathogenesis of hepatic encephalopathy. Metab Brain Dis. 2016 12; 31(6):1259-1267.
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Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Menthol Smokers: Metabolomic Profiling and Smoking Behavior. Cancer Epidemiol Biomarkers Prev. 2017 01; 26(1):51-60.
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Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Metabolomic profiles of current cigarette smokers. Mol Carcinog. 2017 02; 56(2):594-606.
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Sun J, Jin J, Beger RD, Cerniglia CE, Yang M, Chen H. Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena. Toxicol In Vitro. 2016 Oct; 36:133-141.
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Eguchi A, Lazic M, Armando AM, Phillips SA, Katebian R, Maraka S, Quehenberger O, Sears DD, Feldstein AE. Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress. J Mol Med (Berl). 2016 11; 94(11):1241-1253.
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Kieffer DA, Piccolo BD, Vaziri ND, Liu S, Lau WL, Khazaeli M, Nazertehrani S, Moore ME, Marco ML, Martin RJ, Adams SH. Resistant starch alters gut microbiome and metabolomic profiles concurrent with amelioration of chronic kidney disease in rats. Am J Physiol Renal Physiol. 2016 05 01; 310(9):F857-71.
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Kim IY, Suh SH, Lee IK, Wolfe RR. Applications of stable, nonradioactive isotope tracers in in vivo human metabolic research. Exp Mol Med. 2016 Jan 15; 48:e203.
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Shi Q, Yang X, Mattes WB, Mendrick DL, Harrill AH, Beger RD. Circulating mitochondrial biomarkers for drug-induced liver injury. Biomark Med. 2015; 9(11):1215-23.
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James L, Yan K, Pence L, Simpson P, Bhattacharyya S, Gill P, Letzig L, Kearns G, Beger R. Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity. PLoS One. 2015; 10(7):e0131010.
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Piccolo BD, Keim NL, Fiehn O, Adams SH, Van Loan MD, Newman JW. Habitual physical activity and plasma metabolomic patterns distinguish individuals with low vs. high weight loss during controlled energy restriction. J Nutr. 2015 Apr; 145(4):681-90.
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Chun YH, Han K, Park SH, Park KM, Yim HW, Lee WC, Park YG, Park YM. Insulin resistance is associated with intraocular pressure elevation in a non-obese Korean population. PLoS One. 2015; 10(1):e112929.
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Bouhifd M, Beger R, Flynn T, Guo L, Harris G, Hogberg H, Kaddurah-Daouk R, Kamp H, Kleensang A, Maertens A, Odwin-DaCosta S, Pamies D, Robertson D, Smirnova L, Sun J, Zhao L, Hartung T. Quality assurance of metabolomics. ALTEX. 2015; 32(4):319-26.
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Su LJ, Fiehn O, Maruvada P, Moore SC, O'Keefe SJ, Wishart DS, Zanetti KA. The use of metabolomics in population-based research. Adv Nutr. 2014 Nov; 5(6):785-8.
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Fang N, Yu S, Ronis MJ, Badger TM. Matrix effects break the LC behavior rule for analytes in LC-MS/MS analysis of biological samples. Exp Biol Med (Maywood). 2015 Apr; 240(4):488-97.
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Cheema AK, Pathak R, Zandkarimi F, Kaur P, Alkhalil L, Singh R, Zhong X, Ghosh S, Aykin-Burns N, Hauer-Jensen M. Liver metabolomics reveals increased oxidative stress and fibrogenic potential in gfrp transgenic mice in response to ionizing radiation. J Proteome Res. 2014 Jun 06; 13(6):3065-74.
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Church RJ, Wu H, Mosedale M, Sumner SJ, Pathmasiri W, Kurtz CL, Pletcher MT, Eaddy JS, Pandher K, Singer M, Batheja A, Watkins PB, Adkins K, Harrill AH. A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis. Toxicol Sci. 2014 Aug 01; 140(2):481-92.
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Mahapatra S, Hess AM, Johnson JL, Eisenach KD, DeGroote MA, Gitta P, Joloba ML, Kaplan G, Walzl G, Boom WH, Belisle JT. A metabolic biosignature of early response to anti-tuberculosis treatment. BMC Infect Dis. 2014 Jan 31; 14:53.
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Bhattacharyya S, Yan K, Pence L, Simpson PM, Gill P, Letzig LG, Beger RD, Sullivan JE, Kearns GL, Reed MD, Marshall JD, Van Den Anker JN, James LP. Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children. Biomark Med. 2014; 8(2):147-59.
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James LP. Metabolomics: integration of a new "omics" with clinical pharmacology. Clin Pharmacol Ther. 2013 Nov; 94(5):547-51.
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Lu Y, Sun J, Petrova K, Yang X, Greenhaw J, Salminen WF, Beger RD, Schnackenberg LK. Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice. Food Chem Toxicol. 2013 Dec; 62:707-21.
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Patton AL, Seely KA, Chimalakonda KC, Tran JP, Trass M, Miranda A, Fantegrossi WE, Kennedy PD, Dobrowolski P, Radominska-Pandya A, McCain KR, James LP, Endres GW, Moran JH. Targeted metabolomic approach for assessing human synthetic cannabinoid exposure and pharmacology. Anal Chem. 2013 Oct 01; 85(19):9390-9.
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Adams SH, Barnes KM, Odle J. Comparative metabolic physiology in the 'omics' era: a call to arms, paws, flippers, and claws. Adv Nutr. 2013 Sep 01; 4(5):568-9.
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McGill MR, Li F, Sharpe MR, Williams CD, Curry SC, Ma X, Jaeschke H. Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans. Arch Toxicol. 2014 Feb; 88(2):391-401.
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She P, Olson KC, Kadota Y, Inukai A, Shimomura Y, Hoppel CL, Adams SH, Kawamata Y, Matsumoto H, Sakai R, Lang CH, Lynch CJ. Leucine and protein metabolism in obese Zucker rats. PLoS One. 2013; 8(3):e59443.
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Ghosh SP, Singh R, Chakraborty K, Kulkarni S, Uppal A, Luo Y, Kaur P, Pathak R, Kumar KS, Hauer-Jensen M, Cheema AK. Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model. Mol Biosyst. 2013 Apr 05; 9(4):723-31.
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Schnackenberg LK, Sun J, Pence LM, Bhattacharyya S, Gamboa da Costa G, Beger RD. Metabolomics evaluation of hydroxyproline as a potential marker of melamine and cyanuric acid nephrotoxicity in male and female Fischer F344 rats. Food Chem Toxicol. 2012 Nov; 50(11):3978-83.
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McBurney RN, Hines WM, VonTungeln LS, Schnackenberg LK, Beger RD, Moland CL, Han T, Fuscoe JC, Chang CW, Chen JJ, Su Z, Fan XH, Tong W, Booth SA, Balasubramanian R, Courchesne PL, Campbell JM, Graber A, Guo Y, Juhasz P, Li TY, Lynch MD, Morel NM, Plasterer TN, Takach EJ, Zeng C, Beland FA. The liver toxicity biomarker study phase I: markers for the effects of tolcapone or entacapone. Toxicol Pathol. 2012 Aug; 40(6):951-64.
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Sun J, Shannon M, Ando Y, Schnackenberg LK, Khan NA, Portilla D, Beger RD. Serum metabolomic profiles from patients with acute kidney injury: a pilot study. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Apr 15; 893-894:107-13.
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Schnackenberg LK, Sun J, Beger RD. Metabolomics techniques in nanotoxicology studies. Methods Mol Biol. 2012; 926:141-56.
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