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Apoptosis Inducing Factor

"Apoptosis Inducing Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.


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This graph shows the total number of publications written about "Apoptosis Inducing Factor" by people in UAMS Profiles by year, and whether "Apoptosis Inducing Factor" was a major or minor topic of these publications.
Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2003 and 2004 and 2005 and 2007 and 2011 and 2015
To see the data from this visualization as text, click here.