 Immunoglobulin M
"Immunoglobulin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.
| Descriptor ID |
D007075
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| MeSH Number(s) |
D12.776.124.486.485.114.619.574 D12.776.124.790.651.114.619.574 D12.776.377.715.548.114.619.574
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin M".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin M".
This graph shows the total number of publications written about "Immunoglobulin M" by people in UAMS Profiles by year, and whether "Immunoglobulin M" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 0 | 2 | 2 | | 2020 | 0 | 5 | 5 | | 2018 | 1 | 0 | 1 | | 2017 | 1 | 2 | 3 | | 2016 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2007 | 1 | 1 | 2 | | 2006 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1992 | 0 | 2 | 2 | | 1991 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin M" by people in Profiles over the past ten years.
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Palmieri M, Maraka S, Spencer HJ, Thostenson JD, Dishongh K, Knox M, Ussery B, Byrd J, Kuipers JK, Abedzadeh-Anaraki S, Duvoor C, Mao Y, Menon L, Williams JS, Manolagas SC, Jilka RL, Ambrogini E. Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans. Sci Rep. 2025 01 15; 15(1):2109.
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Brown SL, Bauer JJ, Lee J, Ntirandekura E, Stumhofer JS. IgM+ and IgM- memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii. J Leukoc Biol. 2022 11; 112(5):1115-1135.
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Brown NE, Lyons AK, Schuh AJ, Stumpf MM, Harcourt JL, Tamin A, Rasheed MAU, Mills L, Lester SN, Thornburg NJ, Nguyen K, Costantini V, Vinj? J, Huang JY, Gilbert SE, Gable P, Bollinger S, Sabour S, Beshearse E, Surie D, Biedron C, Gregory CJ, Clemmons NS, Whitaker B, Coughlin MM, Seely KA, Garner K, Gulley T, Haney T, Kothari A, Patil N, Halpin AL, McDonald LC, Kutty PK, Brown AC. Descriptive evaluation of antibody responses to severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection in plasma and gingival crevicular fluid in a nursing home cohort-Arkansas, June-August 2020. Infect Control Hosp Epidemiol. 2022 11; 43(11):1610-1617.
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Wang Z, Schmidt F, Weisblum Y, Muecksch F, Barnes CO, Finkin S, Schaefer-Babajew D, Cipolla M, Gaebler C, Lieberman JA, Oliveira TY, Yang Z, Abernathy ME, Huey-Tubman KE, Hurley A, Turroja M, West KA, Gordon K, Millard KG, Ramos V, Da Silva J, Xu J, Colbert RA, Patel R, Dizon J, Unson-O'Brien C, Shimeliovich I, Gazumyan A, Caskey M, Bjorkman PJ, Casellas R, Hatziioannou T, Bieniasz PD, Nussenzweig MC. mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants. Nature. 2021 04; 592(7855):616-622.
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Gaebler C, Wang Z, Lorenzi JCC, Muecksch F, Finkin S, Tokuyama M, Cho A, Jankovic M, Schaefer-Babajew D, Oliveira TY, Cipolla M, Viant C, Barnes CO, Bram Y, Breton G, H?ggl?f T, Mendoza P, Hurley A, Turroja M, Gordon K, Millard KG, Ramos V, Schmidt F, Weisblum Y, Jha D, Tankelevich M, Martinez-Delgado G, Yee J, Patel R, Dizon J, Unson-O'Brien C, Shimeliovich I, Robbiani DF, Zhao Z, Gazumyan A, Schwartz RE, Hatziioannou T, Bjorkman PJ, Mehandru S, Bieniasz PD, Caskey M, Nussenzweig MC. Evolution of antibody immunity to SARS-CoV-2. Nature. 2021 03; 591(7851):639-644.
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Rostad CA, Chahroudi A, Mantus G, Lapp SA, Teherani M, Macoy L, Tarquinio KM, Basu RK, Kao C, Linam WM, Zimmerman MG, Shi PY, Menachery VD, Oster ME, Edupuganti S, Anderson EJ, Suthar MS, Wrammert J, Jaggi P. Quantitative SARS-CoV-2 Serology in Children With Multisystem Inflammatory Syndrome (MIS-C). Pediatrics. 2020 12; 146(6).
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Moura DTH, McCarty TR, Ribeiro IB, Funari MP, Oliveira PVAG, Miranda Neto AA, Monte J?nior ESD, Tustumi F, Bernardo WM, Moura EGH, Thompson CC. Diagnostic Characteristics of Serological-Based COVID-19 Testing: A Systematic Review and Meta-Analysis. Clinics (Sao Paulo). 2020; 75:e2212.
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Zhou X, Bai T, Meckel K, Song J, Jin Y, Kort?m KM, Einsele H, Hou X, Rasche L. COVID-19 infection in patients with multiple myeloma: a German-Chinese experience from W?rzburg and Wuhan. Ann Hematol. 2021 Mar; 100(3):843-846.
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Zhang L, Pang R, Xue X, Bao J, Ye S, Dai Y, Zheng Y, Fu Q, Hu Z, Yi Y. Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19. Aging (Albany NY). 2020 Apr 22; 12(8):6536-6542.
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Li A, Sanchez-Petitto G, Tkaczuk KHR, Nageshwar M, Singh Z, Kocoglu M. An Unusual Cause of a Pathological Vertebral Fracture: Solitary Plasmacytoma. Am J Med Sci. 2020 08; 360(2):206-207.
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Pashov A, Shivarov V, Hadzhieva M, Kostov V, Ferdinandov D, Heintz KM, Pashova S, Todorova M, Vassilev T, Kieber-Emmons T, Meza-Zepeda LA, Hovig E. Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries. Front Immunol. 2019; 10:2796.
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Ambrogini E, Que X, Wang S, Yamaguchi F, Weinstein RS, Tsimikas S, Manolagas SC, Witztum JL, Jilka RL. Oxidation-specific epitopes restrain bone formation. Nat Commun. 2018 06 06; 9(1):2193.
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Campbell JP, Heaney JLJ, Pandya S, Afzal Z, Kaiser M, Owen R, Child JA, Gregory W, Morgan GJ, Jackson GH, Bunce CM, Drayson MT. Active multiple myeloma suppresses and typically eliminates coexisting MGUS. Br J Cancer. 2017 Sep 05; 117(6):835-839.
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Atrash S, Zhang Q, Papanikolaou X, Stein C, Abdallah AO, Barlogie B. Clinical Presentation and Gene Expression Profiling of Immunoglobulin M Multiple Myeloma Compared With Other Myeloma Subtypes and Waldenstr?m Macroglobulinemia. J Glob Oncol. 2018 09; 4:1-8.
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Cao XX, Meng Q, Cai H, He TH, Zhang CL, Su W, Sun J, Li Y, Xu W, Zhou DB, Li J. Detection of MYD88 L265P and WHIM-like CXCR4 mutation in patients with IgM monoclonal gammopathy related disease. Ann Hematol. 2017 Jun; 96(6):971-976.
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McGill MR, Vijayan A, Trulock EP, Witt CA, Kohler GD, Scott MG. Falsely Elevated Plasma Creatinine Due to an Immunoglobulin M Paraprotein. Am J Kidney Dis. 2016 Nov; 68(5):789-792.
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Cao XX, Meng Q, Mao YY, Su W, Zhen JF, Shen KN, Zhang CL, Huang XF, Duan MH, Zhang W, Zhu TN, Cai HC, Chen M, Zhou DB, Li J. The clinical spectrum of IgM monoclonal gammopathy: A single center retrospective study of 377 patients. Leuk Res. 2016 07; 46:85-8.
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