Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Descriptor ID |
D000544
|
MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.087.400.100
|
Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Disease, Alzheimer
- Alzheimer's Disease
- Disease, Alzheimer's
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Senile Dementia, Alzheimer Type
- Dementia, Primary Senile Degenerative
- Dementia, Senile
- Dementias, Senile
- Senile Dementia
- Senile Dementias
- Primary Senile Degenerative Dementia
- Alzheimer Type Senile Dementia
Dementia, Presenile- Dementia, Presenile
- Dementias, Presenile
- Presenile Dementia
- Presenile Dementias
Alzheimer Disease, Early Onset- Alzheimer Disease, Early Onset
- Presenile Alzheimer Dementia
- Alzheimer Dementia, Presenile
- Dementia, Presenile Alzheimer
- Early Onset Alzheimer Disease
|
Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in UAMS Profiles by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
---|
2025 | 20 | 4 | 24 | 2024 | 15 | 1 | 16 | 2023 | 14 | 1 | 15 | 2022 | 11 | 0 | 11 | 2021 | 18 | 1 | 19 | 2020 | 10 | 3 | 13 | 2019 | 4 | 1 | 5 | 2018 | 7 | 3 | 10 | 2017 | 9 | 1 | 10 | 2016 | 4 | 2 | 6 | 2015 | 3 | 0 | 3 | 2014 | 4 | 0 | 4 | 2013 | 3 | 1 | 4 | 2012 | 4 | 0 | 4 | 2011 | 1 | 0 | 1 | 2010 | 7 | 2 | 9 | 2009 | 7 | 2 | 9 | 2008 | 3 | 1 | 4 | 2007 | 2 | 1 | 3 | 2006 | 7 | 1 | 8 | 2005 | 2 | 2 | 4 | 2004 | 16 | 1 | 17 | 2003 | 3 | 0 | 3 | 2002 | 4 | 1 | 5 | 2001 | 1 | 2 | 3 | 2000 | 3 | 0 | 3 | 1998 | 2 | 0 | 2 | 1997 | 5 | 0 | 5 | 1996 | 2 | 0 | 2 | 1995 | 1 | 0 | 1 | 1994 | 3 | 1 | 4 | 1993 | 2 | 0 | 2 | 1991 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Alzheimer Disease" by people in Profiles over the past ten years.
-
Chen H, Qian L, He X, Chen A, Huang Y, Gou Q, Wang Y, Wang Y, Ai X, Zhou Y, Cohen I, Chen Q, Xu H, Bian J. Clinical Trial Eligibility Criteria Decomposition and Parsing with Large Language Models. Stud Health Technol Inform. 2025 Aug 07; 329:688-692.
-
Narasimhappagari J, Liu L, Balasubramaniam M, Ayyadevara S, Griffin WST. When Two Worlds Collide: The Contribution and Association Between Genetics (APOEe4) and Neuroinflammation (IL-1?) in Alzheimer's Neuropathogenesis. Cells. 2025 Aug 07; 14(15).
-
Taylor S, Dunn L, Udeh-Momoh C, Abbott K, Giannakopoulou P, Middleton L, Robinson O, Kalsi J, Kafetsouli D, Ford J. Technology readiness among UK-based cognitively unaffected older adults during the COVID-19 pandemic: potential implications for decentralised alzheimer's disease prevention trials. BMC Geriatr. 2025 Jul 30; 25(1):563.
-
Dai H, Huang Y, Liu Y, He X, Guo J, Prosperi M, Bian J. Variational temporal deconfounder network for individualized treatment effect estimation with longitudinal observational data. J Biomed Inform. 2025 Sep; 169:104880.
-
Martinez-Perez DA, McGlothan JL, Rodichkin AN, Abilmouna K, Bursac Z, Lopera F, Villegas-Lanau CA, Guilarte TR. Amyloid-? plaque-associated microglia drive TSPO upregulation in Alzheimer's disease. Acta Neuropathol. 2025 Jul 17; 150(1):6.
-
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, da Fonseca EL, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Ikeuchi T, Iqbal T, Pathak O, Valladares O, Reyes-Dumeyer D, Kuzma AB, Abner E, Adams LD, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Auerbach S, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Friedland RP, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Go RCP, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kikuchi M, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, Obisesan T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Petrovitch H, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sabbagh M, Sadovnick AD, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, George-Hyslop PS, Starks TD, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsolaki M, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Miyashita A, Byrd GS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. Genome Biol. 2025 Jul 17; 26(1):210.
-
Paley JL, Scheiffele GD, Li Y, Shaaban CE, Wu Y, Anton S, DeKosky S, Bian J, Guo J. Neighborhood deprivation and mortality among people with Alzheimer's disease and related dementia. J Alzheimers Dis. 2025 Aug; 106(4):1415-1424.
-
Liao W, Xuan J, Ryu WI, Bormann MK, Lee Y, Dion H, Evangelista E, Li R, Trambaiolli L, Liu J, Siegel AJ, Forester BP, Cohen BM, Sonntag KC. Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease. Alzheimers Dement. 2025 Jul; 21(7):e70099.
-
Asante J, Nagel CL, Barger SW. Prescription-based association of P-glycoprotein substrates with Alzheimer's disease risk: A nested case-control study. J Alzheimers Dis. 2025 Aug; 106(3):1063-1073.
-
Tang H, Donahoo WT, DeKosky ST, Lee YA, Kotecha P, Svensson M, Bian J, Guo J. Heterogeneous treatment effects of GLP-1RAs and SGLT2is on risk of Alzheimer's disease and related dementia in patients with type 2 diabetes: Insights from a real-world target trial emulation. Alzheimers Dement. 2025 Jun; 21(6):e70313.
-
Verma A, Azhar G, Patyal P, Zhang X, Wei JY. Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer's Disease Pathologies. Cells. 2025 05 30; 14(11).
-
Moorthy S, Dazard JE, Chen Z, Charak R, Palanivel S, Deo S, Al-Kindi SG, Rajagopalan S. Non-traditional socio-environmental and geospatial determinants of Alzheimer's disease-related dementia mortality. Sci Total Environ. 2025 Jul 01; 984:179745.
-
Meng W, Inampudi R, Zhang X, Xu J, Huang Y, Xie M, Bian J, Yin R. An Interpretable Population Graph Network to Identify Rapid Progression of Alzheimer's Disease Using UK Biobank. AMIA Annu Symp Proc. 2024; 2024:808-817.
-
Mainali N, Balasubramaniam M, Pahal S, Griffin WST, Shmookler Reis RJ, Ayyadevara S. Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer's-like neuropathology. Basic Res Cardiol. 2025 Jun; 120(3):489-507.
-
Tang H, Donahoo WT, DeKosky ST, Lee YA, Kotecha P, Svensson M, Bian J, Guo J. GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias. JAMA Neurol. 2025 May 01; 82(5):439-449.
-
Jian X, Zhang D, Yu Z, Xu H, Bian J, Wu Y, Tong J, Chen Y. Leveraging undecided cases in chart-reviewed phenotypes to enhance EHR-based association studies. J Biomed Inform. 2025 Jun; 166:104839.
-
Asante JJ, Barger SW. P-glycoprotein and Alzheimer's Disease: Threats and Opportunities. ASN Neuro. 2025; 17(1):2495632.
-
Zhou M, Tang AS, Zhang H, Xu Z, Ke AMC, Su C, Huang Y, Mantyh WG, Jaffee MS, Rankin KP, DeKosky ST, Zhou J, Guo Y, Bian J, Sirota M, Wang F. Identifying progression subphenotypes of Alzheimer's disease from large-scale electronic health records with machine learning. J Biomed Inform. 2025 May; 165:104820.
-
Tang H, Donahoo WT, DeKosky ST, Lee YA, Svensson M, Bian J, Guo J. Glycated hemoglobin and body mass index as mediators of GLP-1RAs and Alzheimer's disease and related dementias in patients with type 2 diabetes. Alzheimers Dement. 2025 Apr; 21(4):e70161.
-
Pan J, Fan Z, Smith GE, Guo Y, Bian J, Xu J. Federated learning with multi-cohort real-world data for predicting the progression from mild cognitive impairment to Alzheimer's disease. Alzheimers Dement. 2025 Apr; 21(4):e70128.
-
Rajji TK, Baksh SN, Shade DM, Ismail Z, Burhan AM, Okhravi HR, Padala PR, Rosenberg PB, Schneider LS, Porsteinsson AP, Lyketsos CG. Escitalopram for agitation in Alzheimer's dementia: a randomized controlled phase 3 trial. Nat Med. 2025 May; 31(5):1586-1591.
-
Younes K, Johns E, Young CB, Kennedy G, Mukherjee S, Vossler HA, Winer J, Cody K, Henderson VW, Poston KL, Betthauser TJ, Bevis B, Brooks WM, Burns JM, Coombes SA, DeCarli C, DiFilippo FP, Duara R, Fan AP, Gibbons LE, Golde T, Johnson SC, Lepping RJ, Leverenz J, McDougall S, Rogalski E, Sanders E, Pasaye J, Sridhar J, Saykin AJ, Sridharan A, Swerdlow R, Trittschuh EH, Vaillancourt D, Vidoni E, Wang WE, Mez J, Hohman TJ, Tosun D, Biber S, Kukull WA, Crane PK, Mormino EC. Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort. Alzheimers Dement. 2025 Mar; 21(3):e70075.
-
Canet G, Da Gama Monteiro F, Rocaboy E, Diego-Diaz S, Khelaifia B, Godbout K, Lachhab A, Kim J, Valencia DI, Yin A, Wu HT, Howell J, Blank E, Lalibert? F, Fortin N, Boscher E, Fereydouni-Forouzandeh P, Champagne S, Guisle I, H?bert SS, Pernet V, Liu H, Lu W, Debure L, Rapoport DM, Ayappa I, Varga AW, Parekh A, Osorio RS, Lacroix S, Burns MP, Lucey BP, Blessing EM, Planel E. Sleep-wake variation in body temperature regulates tau secretion and correlates with CSF and plasma tau. J Clin Invest. 2025 Feb 04; 135(7).
-
Nehra G, Maloney BJ, Smith RR, Chumboatong W, Abner EL, Nelson PT, Bauer B, Hartz AMS. Plasma S100? is a predictor for pathology and cognitive decline in Alzheimer's disease. Fluids Barriers CNS. 2025 Jan 09; 22(1):4.
-
Manfredi JN, Gupta SK, Vyavahare S, Deak F, Lu X, Buddha L, Wankhade U, Lohakare J, Isales C, Fulzele S. Gut microbiota dysbiosis in Alzheimer's disease (AD): Insights from human clinical studies and the mouse AD models. Physiol Behav. 2025 Mar 01; 290:114778.
-
Sankhe K, Tumati S, Perin J, Rivet L, Vieira D, Rosenberg PB, Herrmann N, Shade D, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey AI, Mintzer J, Lanct?t KL. Correlation between changes in apathy and cognition in Alzheimer's disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2). Int Psychogeriatr. 2025 Mar; 37(2):100012.
-
Tumati S, Herrmann N, Perin J, Rosenberg PB, Lerner AJ, Mintzer J, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Shade D, Lanct?t KL. Measuring clinically relevant change in apathy symptoms in ADMET and ADMET 2. Int Psychogeriatr. 2024 12; 36(12):1232-1244.
-
Li YB, Fu Q, Guo M, Du Y, Chen Y, Cheng Y. MicroRNAs: pioneering regulators in Alzheimer's disease pathogenesis, diagnosis, and therapy. Transl Psychiatry. 2024 Sep 10; 14(1):367.
-
Bornhorst JA, Algeciras-Schimnich A. Proteomic Identification of Plasma Proteins Associated with Future Dementia Development. Clin Chem. 2024 Sep 03; 70(9):1092-1095.
-
Schartz ND, Liang HY, Carvalho K, Chu SH, Mendoza-Arvilla A, Petrisko TJ, Gomez-Arboledas A, Mortazavi A, Tenner AJ. C5aR1 antagonism suppresses inflammatory glial responses and alters cellular signaling in an Alzheimer's disease mouse model. Nat Commun. 2024 Aug 15; 15(1):7028.
-
Cohen BM, Sonntag KC. Identifying the earliest-occurring clinically targetable precursors of late-onset Alzheimer's disease. EBioMedicine. 2024 Aug; 106:105238.
-
Li W, Petersen RC, Algeciras-Schimnich A, Cogswell PM, Bornhorst JA, Kremers WK, Boeve BF, Jones DT, Botha H, Ramanan VK, Knopman DS, Savica R, Josephs KA, Cliatt-Brown C, Andersen E, Day GS, Graff-Radford NR, Ertekin-Taner N, Lachner C, Wicklund M, van Harten A, Woodruff BK, Caselli RJ, Graff-Radford J. Alzheimer Disease Cerebrospinal Fluid Biomarkers in a Tertiary Neurology Practice. Mayo Clin Proc. 2024 Aug; 99(8):1284-1296.
-
Soleimani-Meigooni DN, Smith R, Provost K, Lesman-Segev OH, Allen IE, Chen MK, Cho H, Edwards L, Janelidze S, La Joie R, Mundada N, Ossenkoppele R, Stomrud E, Strandberg O, Strom A, Boxer AL, Dage JL, Gorno-Tempini ML, Kramer JH, Miller BL, Rojas JC, Rosen HJ, Lyoo CH, Hansson O, Rabinovici GD. Head-to-Head Comparison of Tau and Amyloid Positron Emission Tomography Visual Reads for Differential Diagnosis of Neurodegenerative Disorders: An International, Multicenter Study. Ann Neurol. 2024 Sep; 96(3):476-487.
-
Wang C, Acosta D, McNutt M, Bian J, Ma A, Fu H, Ma Q. A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD). Nat Commun. 2024 Jun 06; 15(1):4710.
-
Zeng L, Perin J, Gross AL, Shade D, Lanct?t KL, Lerner AJ, Mintzer JE, Brawman-Mintzer O, Padala PR, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Herrmann N, Rosenberg PB. Adverse effects of methylphenidate for apathy in patients with Alzheimer's disease (ADMET2 trial). Int J Geriatr Psychiatry. 2024 06; 39(6):e6108.
-
Gendron WH, Fertan E, Roddick KM, Wong AA, Maliougina M, Hiani YE, Anini Y, Brown RE. Intranasal insulin treatment ameliorates spatial memory, muscular strength, and frailty deficits in 5xFAD mice. Physiol Behav. 2024 Jul 01; 281:114583.
-
Younes K, Smith V, Johns E, Carlson ML, Winer J, He Z, Henderson VW, Greicius MD, Young CB, Mormino EC. Temporal tau asymmetry spectrum influences divergent behavior and language patterns in Alzheimer's disease. Brain Behav Immun. 2024 Jul; 119:807-817.
-
O'Leary TP, Brown RE. Age-related changes in species-typical behaviours in the 5xFAD mouse model of Alzheimer's disease from 4 to 16 months of age. Behav Brain Res. 2024 05 08; 465:114970.
-
Verma A, Azhar G, Patyal P, Zhang W, Zhang X, Wei JY. Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells. Geroscience. 2024 Oct; 46(5):4315-4332.
-
Liu J, Xu J, Jia L, Zhou Y, Fu Q, Wang Y, Mu D, Wang D, Li N, Hou Y. Pterostilbene nanoemulsion promotes Nrf2 signaling pathway to downregulate oxidative stress for treating Alzheimer's disease. Int J Pharm. 2024 Apr 25; 655:124002.
-
Albert-Gasco H, Smith HL, Alvarez-Castelao B, Swinden D, Halliday M, Janaki-Raman S, Butcher AJ, Mallucci GR. Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration. Brain. 2024 02 01; 147(2):649-664.
-
Algeciras-Schimnich A, Bornhorst JA. Importance of cerebrospinal fluid (CSF) collection protocol for the accurate diagnosis of Alzheimer's disease when using CSF biomarkers. Alzheimers Dement. 2024 05; 20(5):3657-3658.
-
Gomez-Arboledas A, Fonseca MI, Kramar E, Chu SH, Schartz ND, Selvan P, Wood MA, Tenner AJ. C5aR1 signaling promotes region- and age-dependent synaptic pruning in models of Alzheimer's disease. Alzheimers Dement. 2024 03; 20(3):2173-2190.
-
Xu J, Yin R, Huang Y, Gao H, Wu Y, Guo J, Smith GE, DeKosky ST, Wang F, Guo Y, Bian J. Identification of Outcome-Oriented Progression Subtypes from Mild Cognitive Impairment to Alzheimer's Disease Using Electronic Health Records. AMIA Annu Symp Proc. 2023; 2023:764-773.
-
Balasubramaniam M, Narasimhappagari J, Liu L, Ganne A, Ayyadevara S, Atluri R, Ayyadevara H, Caldwell G, Shmookler Reis RJ, Barger SW, Griffin WST. Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer's disease by targeted small molecules. Commun Biol. 2024 01 08; 7(1):60.
-
Kintz S, Kim H, Wright HH. A preliminary investigation on core lexicon analysis in dementia of the Alzheimer's type. Int J Lang Commun Disord. 2024 Jul-Aug; 59(4):1336-1350.
-
Isik AT, Kaya D, Gokden M. Brain Banking in Dementia Studies. Methods Mol Biol. 2024; 2785:287-295.
-
Zang C, Zhang H, Xu J, Zhang H, Fouladvand S, Havaldar S, Cheng F, Chen K, Chen Y, Glicksberg BS, Chen J, Bian J, Wang F. High-throughput target trial emulation for Alzheimer's disease drug repurposing with real-world data. Nat Commun. 2023 12 11; 14(1):8180.
-
Membreno R, Thomas KR, Calcetas AT, Edwards L, Bordyug M, Showell M, Stanfill M, Brenner EK, Walker KS, Rotblatt LJ, Brickman AM, Edmonds EC, Bangen KJ. Regional White Matter Hyperintensities Relate to Specific Cognitive Abilities in Older Adults Without Dementia. Alzheimer Dis Assoc Disord. 2023 Oct-Dec 01; 37(4):303-309.
-
Bose C, Kshirsagar S, Vijayan M, Kumar S, Singh SP, Hindle A, Reddy PH. The role of RLIP76 in oxidative stress and mitochondrial dysfunction: Evidence based on autopsy brains from Alzheimer's disease patients. Biochim Biophys Acta Mol Basis Dis. 2024 02; 1870(2):166932.
-
Mainali N, Li X, Wang X, Balasubramaniam M, Ganne A, Kore R, Shmookler Reis RJ, Mehta JL, Ayyadevara S. Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain. Mol Cell Biochem. 2024 Oct; 479(10):2741-2753.
-
Burroughs AW, Krain LP. What Might Aducanumab Teach Us About Clinicians' Judgment About Whether to Recommend Emerging Alzheimer's Interventions? AMA J Ethics. 2023 10 01; 25(10):E777-782.
-
Nosheny RL, Yen D, Howell T, Camacho M, Moulder K, Gummadi S, Bui C, Kannan S, Ashford MT, Knight K, Mayo C, McMillan M, Petersen RC, Stricker NH, Roberson ED, Chambless C, Gersteneker A, Martin R, Kennedy R, Zhang Y, Kukull W, Flenniken D, Fockler J, Truran D, Mackin RS, Weiner MW, Morris JC, Li Y. Evaluation of the Electronic Clinical Dementia Rating for Dementia Screening. JAMA Netw Open. 2023 09 05; 6(9):e2333786.
-
Espahbodi S, Hogervorst E, Macnab TP, Thanoon A, Fernandes GS, Millar B, Duncan A, Goodwin M, Batt M, Fuller CW, Fuller G, Ferguson E, Bast T, Doherty M, Zhang W. Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players. JAMA Netw Open. 2023 07 03; 6(7):e2323822.
-
Reddy PH, Kshirsagar S, Bose C, Pradeepkiran JA, Hindle A, Singh SP, Reddy AP, Baig J. Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights. Cells. 2023 06 16; 12(12).
-
Lanct?t KL, Rivet L, Tumati S, Perin J, Sankhe K, Vieira D, Mintzer J, Rosenberg PB, Shade D, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey AI, Padala KP, Herrmann N. Heterogeneity of Response to Methylphenidate in Apathetic Patients in the ADMET 2 Trial. Am J Geriatr Psychiatry. 2023 12; 31(12):1077-1087.
-
Reddy PH, Kshirsagar S, Bose C, Pradeepkiran JA, Hindle A, Singh SP, Reddy AP. Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights. Biochim Biophys Acta Mol Basis Dis. 2023 10; 1869(7):166759.
-
Manna PR, Bose C, Reddy PH. Downregulation of StAR driven neurosteroid biosynthesis as a distinctive feature in the brains of Alzheimer's disease patients. Biochim Biophys Acta Mol Basis Dis. 2023 08; 1869(6):166757.
-
Chen A, Li Q, He X, Jaffee MS, Hogan WR, Wang F, Guo Y, Bian J. Impacts of Eligibility Criteria on Trial Participants' Age in Alzheimer's Disease Clinical Trials. AMIA Annu Symp Proc. 2022; 2022:368-376.
-
Sung JH, Ou Y, Barger SW. Amyloid ?-Peptide Effects on Glucose Regulation Are Dependent on Apolipoprotein E Genotype. eNeuro. 2023 04; 10(4).
-
Lanct?t KL, Chen C, Mah E, Kiss A, Li A, Shade D, Scherer RW, Vieira D, Coulibaly H, Rosenberg PB, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Burke WJ, Mintzer J, Herrmann N. Cost consequence analysis of Apathy in Dementia Methylphenidate Trial 2 (ADMET 2). Int Psychogeriatr. 2023 11; 35(11):664-672.
-
Alkharisi B, Dostzada K, Kaur H, Kumar M, Wei JY, Azhar G. The Importance of Dopamine Deficiency Evaluation in Non-Alzheimer Disease Dementias. Am J Case Rep. 2023 Apr 05; 24:e938344.
-
Li Q, Yang X, Xu J, Guo Y, He X, Hu H, Lyu T, Marra D, Miller A, Smith G, DeKosky S, Boyce RD, Schliep K, Shenkman E, Maraganore D, Wu Y, Bian J. Early prediction of Alzheimer's disease and related dementias using real-world electronic health records. Alzheimers Dement. 2023 08; 19(8):3506-3518.
-
Fertan E, Gendron WH, Wong AA, Hanson GM, Brown RE, Weaver ICG. Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42 in Alzheimer's disease. Sci Rep. 2023 02 04; 13(1):2043.
-
Giannos P, Prokopidis K, Church DD, Kirk B, Morgan PT, Lochlainn MN, Macpherson H, Woods DR, Ispoglou T. Associations of Bioavailable Serum Testosterone With Cognitive Function in Older Men: Results From the National Health and Nutrition Examination Survey. J Gerontol A Biol Sci Med Sci. 2023 01 26; 78(1):151-157.
-
Cohen BM, Sonntag KC. The complex determinants of Alzheimer's-type dementias. Aging (Albany NY). 2023 01 04; 15(1):1-3.
-
Edwards L, Thomas KR, Weigand AJ, Edmonds EC, Clark AL, Walker KS, Brenner EK, Nation DA, Maillard P, Bondi MW, Bangen KJ. White Matter Hyperintensity Volume and Amyloid-PET Synergistically Impact Memory Independent of Tau-PET in Older Adults Without Dementia. J Alzheimers Dis. 2023; 94(2):695-707.
-
Mani S, Dubey R, Lai IC, Babu MA, Tyagi S, Swargiary G, Mody D, Singh M, Agarwal S, Iqbal D, Kumar S, Hamed M, Sachdeva P, Almutary AG, Albadrani HM, Ojha S, Singh SK, Jha NK. Oxidative Stress and Natural Antioxidants: Back and Forth in the Neurological Mechanisms of Alzheimer's Disease. J Alzheimers Dis. 2023; 96(3):877-912.
-
Chen Z, Zhang H, Yang X, Wu S, He X, Xu J, Guo J, Prosperi M, Wang F, Xu H, Chen Y, Hu H, DeKosky ST, Farrer M, Guo Y, Wu Y, Bian J. Assess the documentation of cognitive tests and biomarkers in electronic health records via natural language processing for Alzheimer's disease and related dementias. Int J Med Inform. 2023 02; 170:104973.
-
Ganne A, Balasubramaniam M, Mainali N, Atluri P, Shmookler Reis RJ, Ayyadevara S. Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases. Int J Mol Sci. 2022 Dec 07; 23(24).
-
Romero JR, Pinheiro A, Aparicio HJ, DeCarli CS, Demissie S, Seshadri S. MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study. Neurology. 2022 Dec 05; 99(23):e2561-e2571.
-
Chen PC, Han X, Shaw TI, Fu Y, Sun H, Niu M, Wang Z, Jiao Y, Teubner BJW, Eddins D, Beloate LN, Bai B, Mertz J, Li Y, Cho JH, Wang X, Wu Z, Liu D, Poudel S, Yuan ZF, Mancieri A, Low J, Lee HM, Patton MH, Earls LR, Stewart E, Vogel P, Hui Y, Wan S, Bennett DA, Serrano GE, Beach TG, Dyer MA, Smeyne RJ, Moldoveanu T, Chen T, Wu G, Zakharenko SS, Yu G, Peng J. Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment. Nat Aging. 2022 10; 2(10):923-940.
-
Gomez-Arboledas A, Carvalho K, Balderrama-Gutierrez G, Chu SH, Liang HY, Schartz ND, Selvan P, Petrisko TJ, Pan MA, Mortazavi A, Tenner AJ. C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2022 08 17; 10(1):116.
-
Kumari S, Maddeboina K, Bachu RD, Boddu SHS, Trippier PC, Tiwari AK. Pivotal role of nitrogen heterocycles in Alzheimer's disease drug discovery. Drug Discov Today. 2022 10; 27(10):103322.
-
Carvalho K, Schartz ND, Balderrama-Gutierrez G, Liang HY, Chu SH, Selvan P, Gomez-Arboledas A, Petrisko TJ, Fonseca MI, Mortazavi A, Tenner AJ. Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression. J Neuroinflammation. 2022 Jul 11; 19(1):178.
-
Simanaviciute U, Brown RE, Wong A, Fertan E, Grant RA. Abnormal whisker movements in the 3xTg-AD mouse model of Alzheimer's disease. Genes Brain Behav. 2022 11; 21(8):e12813.
-
Ryu WI, Shen M, Lee Y, Healy RA, Bormann MK, Cohen BM, Sonntag KC. Nicotinamide riboside and caffeine partially restore diminished NAD availability but not altered energy metabolism in Alzheimer's disease. Aging Cell. 2022 07; 21(7):e13658.
-
Calcetas AT, Thomas KR, Edmonds EC, Holmqvist SL, Edwards L, Bordyug M, Delano-Wood L, Brickman AM, Bondi MW, Bangen KJ. Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment. Neurobiol Aging. 2022 10; 118:1-8.
-
Hindle A, Singh SP, Pradeepkiran JA, Bose C, Vijayan M, Kshirsagar S, Sawant NA, Reddy PH. Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer's Disease? Int J Mol Sci. 2022 May 29; 23(11).
-
Zhao YL, Ou YN, Ma YH, Huang YY, Bi YL, Tan L, Yu JT. Association between Life's Simple 7 and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact adults: the CABLE study. Alzheimers Res Ther. 2022 05 26; 14(1):74.
-
Johansen M, Joensen S, Restorff M, St?r? T, Christy D, Gustavsson EK, Bian J, Guo Y, Farrer MJ, Petersen MS. Polygenic risk of Alzheimer's disease in the Faroe Islands. Eur J Neurol. 2022 Aug; 29(8):2192-2200.
-
Turcu AL, Companys-Alemany J, Phillips MB, Patel DS, Gri??n-Ferr? C, Loza MI, Brea JM, P?rez B, Soto D, Sureda FX, Kurnikova MG, Johnson JW, Pall?s M, V?zquez S. Design, synthesis, and in?vitro and in?vivo characterization of new memantine analogs for Alzheimer's disease. Eur J Med Chem. 2022 Jun 05; 236:114354.
-
Guo Y, Li Q, Yang X, Jaffee MS, Wu Y, Wang F, Bian J. Prevalence of Alzheimer's and Related Dementia Diseases and Risk Factors Among Transgender Adults, Florida, 2012?2020. Am J Public Health. 2022 05; 112(5):754-757.
-
O'Leary TP, Brown RE. Visuo-spatial learning and memory impairments in the 5xFAD mouse model of Alzheimer's disease: Effects of age, sex, albinism, and motor impairments. Genes Brain Behav. 2022 04; 21(4):e12794.
-
Fertan E, Brown RE. Age-related deficits in working memory in 5xFAD mice in the Hebb-Williams maze. Behav Brain Res. 2022 04 29; 424:113806.
-
Roddick KM, Fertan E, Schellinck HM, Brown RE. A Signal Detection Analysis of Olfactory Learning in 12-Month-Old 5xFAD Mice. J Alzheimers Dis. 2022; 88(1):37-44.
-
Wu S, Zhou J, Zhang H, Barger SW. Serine Racemase Expression Differentiates Aging from Alzheimer's Brain. Curr Alzheimer Res. 2022; 19(7):494-502.
-
Tasker R, Rowlands J, Ahmed Z, Di Pietro V. Co-Expression Network Analysis of Micro-RNAs and Proteins in the Alzheimer's Brain: A Systematic Review of Studies in the Last 10 Years. Cells. 2021 12 09; 10(12).
-
Xiong LL, Xue LL, Du RL, Niu RZ, Chen L, Chen J, Hu Q, Tan YX, Shang HF, Liu J, Yu CY, Wang TH. Single-cell RNA sequencing reveals B cell-related molecular biomarkers for Alzheimer's disease. Exp Mol Med. 2021 12; 53(12):1888-1901.
-
Dunn LB, Kim JP, Rostami M, Mondal S, Ryan K, Waraich A, Roberts LW, Palmer BW. Stakeholders' Perspectives regarding Participation in Neuromodulation-Based Dementia Intervention Research. J Empir Res Hum Res Ethics. 2022 Feb-Apr; 17(1-2):29-38.
-
Awasthi S, Hindle A, Sawant NA, George M, Vijayan M, Kshirsagar S, Morton H, Bunquin LE, Palade PT, Lawrence JJ, Khan H, Bose C, Reddy PH, Singh SP. RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease. Cells. 2021 11 10; 10(11).
-
Mintzer J, Lanct?t KL, Scherer RW, Rosenberg PB, Herrmann N, van Dyck CH, Padala PR, Brawman-Mintzer O, Porsteinsson AP, Lerner AJ, Craft S, Levey AI, Burke W, Perin J, Shade D. Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial. JAMA Neurol. 2021 11 01; 78(11):1324-1332.
-
Morris JK, McCoin CS, Fuller KN, John CS, Wilkins HM, Green ZD, Wang X, Sharma P, Burns JM, Vidoni ED, Mahnken JD, Shankar K, Swerdlow RH, Thyfault JP. Mild Cognitive Impairment and Donepezil Impact Mitochondrial Respiratory Capacity in Skeletal Muscle. Function (Oxf). 2021; 2(6):zqab045.
-
Ayyadevara S, Ganne A, Balasubramaniam M, Shmookler Reis RJ. Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration. Metab Brain Dis. 2022 01; 37(1):147-152.
-
Zhang Y, Bian J, Huo J, Yang S, Guo Y, Shao H. Comparing the downstream costs and healthcare utilization associated with the use of low-dose computed tomography (LDCT) in lung cancer screening in patients with and without alzheimer's disease and related dementias (ADRD). Curr Med Res Opin. 2021 10; 37(10):1731-1737.
-
Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. Bioorg Med Chem. 2021 09 01; 45:116311.
-
Rashid T, Abdulkadir A, Nasrallah IM, Ware JB, Liu H, Spincemaille P, Romero JR, Bryan RN, Heckbert SR, Habes M. DEEPMIR: a deep neural network for differential detection of cerebral microbleeds and iron deposits in MRI. Sci Rep. 2021 07 08; 11(1):14124.
-
Mortby ME, Adler L, Ag?era-Ortiz L, Bateman DR, Brodaty H, Cantillon M, Geda YE, Ismail Z, Lanct?t KL, Marshall GA, Padala PR, Politis A, Rosenberg PB, Siarkos K, Sultzer DL, Theleritis C. Apathy as a Treatment Target in Alzheimer's Disease: Implications for Clinical Trials. Am J Geriatr Psychiatry. 2022 02; 30(2):119-147.
-
Abdelmeguid NE, Khalil MIM, Elhabet R, Sultan AS, Salam SA. Combination of docosahexaenoic acid and Ginko biloba extract improves cognitive function and hippocampal tissue damages in a mouse model of Alzheimer's disease. J Chem Neuroanat. 2021 10; 116:101995.
-
Sharma VK, Singh TG, Garg N, Dhiman S, Gupta S, Rahman MH, Najda A, Walasek-Janusz M, Kamel M, Albadrani GM, Akhtar MF, Saleem A, Altyar AE, Abdel-Daim MM. Dysbiosis and Alzheimer's Disease: A Role for Chronic Stress? Biomolecules. 2021 04 30; 11(5).
-
Ryu WI, Bormann MK, Shen M, Kim D, Forester B, Park Y, So J, Seo H, Sonntag KC, Cohen BM. Brain cells derived from Alzheimer's disease patients have multiple specific innate abnormalities in energy metabolism. Mol Psychiatry. 2021 10; 26(10):5702-5714.
-
Cho Y, Han K, Kim DH, Park YM, Yoon KH, Kim MK, Lee SH. Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study. Endocrinol Metab (Seoul). 2021 04; 36(2):424-435.
-
Vijayan M, Bose C, Reddy PH. Protective effects of a small molecule inhibitor, DDQ against amyloid beta in Alzheimer's disease. Mitochondrion. 2021 07; 59:17-29.
-
Shmookler Reis RJ, Atluri R, Balasubramaniam M, Johnson J, Ganne A, Ayyadevara S. "Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation. Aging Cell. 2021 05; 20(5):e13326.
-
Harrison TC, Blozis SA, Schmidt B, Johnson A, Moreno R, Mead S, Gayle M. Music Compared with Auditory Books: A Randomized Controlled Study Among Long-Term Care Residents with Alzheimer's Disease or Related Dementia. J Am Med Dir Assoc. 2021 07; 22(7):1415-1420.
-
Gendron WH, Fertan E, Pelletier S, Roddick KM, O'Leary TP, Anini Y, Brown RE. Age related weight loss in female 5xFAD mice from 3 to 12 months of age. Behav Brain Res. 2021 05 21; 406:113214.
-
Arya A, Chahal R, Rao R, Rahman MH, Kaushik D, Akhtar MF, Saleem A, Khalifa SMA, El-Seedi HR, Kamel M, Albadrani GM, Abdel-Daim MM, Mittal V. Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer's Disease Therapy. Biomolecules. 2021 02 25; 11(3).
-
Huang SJ, Ma YH, Bi YL, Shen XN, Hou XH, Cao XP, Ou YN, Zhao B, Dong Q, Tan L, Yu JT. Metabolically healthy obesity and lipids may be protective factors for pathological changes of alzheimer's disease in cognitively normal adults. J Neurochem. 2021 05; 157(3):834-845.
-
Seghezzo G, Van Hoecke Y, James L, Davoren D, Williamson E, Pearce N, McElvenny D, Gallo V. Feasibility study of assessing the Preclinical Alzheimer Cognitive Composite (PACC) score via videoconferencing. J Neurol. 2021 Jun; 268(6):2228-2237.
-
Duan R, Chen Z, Tong J, Luo C, Lyu T, Tao C, Maraganore D, Bian J, Chen Y. Leverage Real-world Longitudinal Data in Large Clinical Research Networks for Alzheimer's Disease and Related Dementia (ADRD). AMIA Annu Symp Proc. 2020; 2020:393-401.
-
Gupta HV, Beach TG, Mehta SH, Shill HA, Driver-Dunckley E, Sabbagh MN, Belden CM, Liebsack C, Dugger BN, Serrano GE, Sue LI, Siderowf A, Pontecorvo MJ, Mintun MA, Joshi AD, Adler CH. Clinicopathological Correlation: Dopamine and Amyloid PET Imaging with Neuropathology in Three Subjects Clinically Diagnosed with Alzheimer's Disease or Dementia with Lewy Bodies. J Alzheimers Dis. 2021; 80(4):1603-1612.
-
Wang ZT, Shen XN, Ma YH, Ou YN, Dong PQ, Tan PL, Yu PJ. Associations of the Rate of Change in Geriatric Depression Scale with Amyloid and Cerebral Glucose Metabolism in Cognitively Normal Older Adults: A Longitudinal Study. J Affect Disord. 2021 02 01; 280(Pt A):77-84.
-
Tsou AY, Bulova P, Capone G, Chicoine B, Gelaro B, Harville TO, Martin BA, McGuire DE, McKelvey KD, Peterson M, Tyler C, Wells M, Whitten MS. Medical Care of Adults With Down Syndrome: A Clinical Guideline. JAMA. 2020 10 20; 324(15):1543-1556.
-
Dungan CM, Valentino T, Vechetti IJ, Zdunek CJ, Murphy MP, Lin AL, McCarthy JJ, Peterson CA. Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and A?1-42 in female 3xTg-AD mice. J Neurophysiol. 2020 12 01; 124(6):1571-1577.
-
Hendrix RD, Ou Y, Davis JE, Odle AK, Groves TR, Allen AR, Childs GV, Barger SW. Alzheimer amyloid-?- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood. Neurobiol Aging. 2021 01; 97:73-88.
-
Arya S, Ganguly P, Arsiccio A, Claud SL, Trapp B, Schonfeld GE, Liu X, Lazar Cantrell K, Shea JE, Bowers MT. Terminal Capping of an Amyloidogenic Tau Fragment Modulates Its Fibrillation Propensity. J Phys Chem B. 2020 10 08; 124(40):8772-8783.
-
Hermosura AH, Noonan CJ, Fyfe-Johnson AL, Seto TB, Kaholokula JK, MacLehose RF. Hospital Disparities between Native Hawaiian and Other Pacific Islanders and Non-Hispanic Whites with Alzheimer's Disease and Related Dementias. J Aging Health. 2020 12; 32(10):1579-1590.
-
Lanct?t KL, Scherer RW, Li A, Vieira D, Coulibaly H, Rosenberg PB, Herrmann N, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Burke WJ, Mintzer JE. Measuring Apathy in Alzheimer's Disease in the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): A Comparison of Instruments. Am J Geriatr Psychiatry. 2021 01; 29(1):81-89.
-
Isik AT, Danyeli AE, Kaya D, Soysal P, Karabay N, Gokden M. The importance of brain banking for dementia practice: the first experience of Turkey. Cell Tissue Bank. 2020 Sep; 21(3):367-375.
-
van Dyck CH, Arnsten AFT, Padala PR, Brawman-Mintzer O, Lerner AJ, Porsteinsson AP, Scherer RW, Levey AI, Herrmann N, Jamil N, Mintzer JE, Lanct?t KL, Rosenberg PB. Neurobiologic Rationale for Treatment of Apathy in Alzheimer's Disease With Methylphenidate. Am J Geriatr Psychiatry. 2021 01; 29(1):51-62.
-
Bernath MM, Bhattacharyya S, Nho K, Barupal DK, Fiehn O, Baillie R, Risacher SL, Arnold M, Jacobson T, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R, Saykin AJ. Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers. Neurology. 2020 05 19; 94(20):e2088-e2098.
-
Padala PR, Padala KP, Samant RS, James GA. Improvement of neuronal integrity with methylphenidate treatment for apathy in Alzheimer's disease. Int Psychogeriatr. 2020 04; 32(4):539-540.
-
Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, Shaw TI, Cho JH, Zhou S, Wang H, Niu M, Mancieri A, Messler KA, Sun X, Wu Z, Pagala V, High AA, Bi W, Zhang H, Chi H, Haroutunian V, Zhang B, Beach TG, Yu G, Peng J. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. 2020 03 18; 105(6):975-991.e7.
-
Padala PR, Boozer EM, Lensing SY, Parkes CM, Hunter CR, Dennis RA, Caceda R, Padala KP. Neuromodulation for Apathy in Alzheimer's Disease: A Double-Blind, Randomized, Sham-Controlled Pilot Study. J Alzheimers Dis. 2020; 77(4):1483-1493.
-
Ahmad RHMA, Fakhoury M, Lawand N. Electromagnetic Field in Alzheimer's Disease: A Literature Review of Recent Preclinical and Clinical Studies. Curr Alzheimer Res. 2020; 17(11):1001-1012.
-
Tomoto T, Sugawara J, Tarumi T, Chiles C, Curtis B, Pasha EP, Cullum CM, Zhang R. Carotid Arterial Stiffness and Cerebral Blood Flow in Amnestic Mild Cognitive Impairment. Curr Alzheimer Res. 2020; 17(12):1115-1125.
-
Balasubramaniam M, Parcon PA, Bose C, Liu L, Jones RA, Farlow MR, Mrak RE, Barger SW, Griffin WST. Interleukin-1? drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site. J Neuroinflammation. 2019 Dec 27; 16(1):275.
-
Melchior B, Mittapalli GK, Lai C, Duong-Polk K, Stewart J, G?ner B, Hofilena B, Tjitro A, Anderson SD, Herman DS, Dellamary L, Swearingen CJ, Sunil KC, Yazici Y. Tau pathology reduction with SM07883, a novel, potent, and selective oral DYRK1A inhibitor: A potential therapeutic for Alzheimer's disease. Aging Cell. 2019 10; 18(5):e13000.
-
Fertan E, Wong AA, Vienneau NA, Brown RE. Age and sex differences in motivation and spatial working memory in 3xTg-AD mice in the Hebb-Williams maze. Behav Brain Res. 2019 09 16; 370:111937.
-
G?r E, Fertan E, Alkins K, Wong AA, Brown RE, Balci F. Interval timing is disrupted in female 5xFAD mice: An indication of altered memory processes. J Neurosci Res. 2019 07; 97(7):817-827.
-
Fertan E, Rodrigues GJ, Wheeler RV, Goguen D, Wong AA, James H, Stadnyk A, Brown RE, Weaver ICG. Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease. Am J Pathol. 2019 07; 189(7):1435-1450.
-
Fouda AY, Fagan SC, Ergul A. Brain Vasculature and Cognition. Arterioscler Thromb Vasc Biol. 2019 04; 39(4):593-602.
-
Goodwill AM, Campbell S, Henderson VW, Gorelik A, Dennerstein L, McClung M, Szoeke C. Robust norms for neuropsychological tests of verbal episodic memory in Australian women. Neuropsychology. 2019 May; 33(4):581-595.
-
Karim R, Koc M, Rettberg JR, Hodis HN, Henderson VW, St John JA, Allayee H, Brinton RD, Mack WJ. Apolipoprotein E4 genotype in combination with poor metabolic profile is associated with reduced cognitive performance in healthy postmenopausal women: implications for late onset Alzheimer's disease. Menopause. 2019 01; 26(1):7-15.
-
Padala KP, Hunter CR, Parkes CM, Lensing SY, Padala PR. Repetitive Transcranial Magnetic Stimulation Improves Executive Function and Music Rhythm. J Neuropsychiatry Clin Neurosci. 2019 Spring; 31(2):178-180.
-
Hu L, Zhang R, Yuan Q, Gao Y, Yang MQ, Zhang C, Huang J, Sun Y, Yang W, Yang JY, Min ZL, Cheng J, Deng Y, Hu X. The emerging role of microRNA-4487/6845-3p in Alzheimer's disease pathologies is induced by A?25-35 triggered in SH-SY5Y cell. BMC Syst Biol. 2018 12 14; 12(Suppl 7):119.
-
O'Leary TP, Mantolino HM, Stover KR, Brown RE. Age-related deterioration of motor function in male and female 5xFAD mice from 3 to 16 months of age. Genes Brain Behav. 2020 03; 19(3):e12538.
-
Iadanza MG, Jackson MP, Hewitt EW, Ranson NA, Radford SE. A new era for understanding amyloid structures and disease. Nat Rev Mol Cell Biol. 2018 12; 19(12):755-773.
-
G?r E, Fertan E, Kosel F, Wong AA, Balci F, Brown RE. Sex differences in the timing behavior performance of 3xTg-AD and wild-type mice in the peak interval procedure. Behav Brain Res. 2019 03 15; 360:235-243.
-
Grant RA, Wong AA, Fertan E, Brown RE. Whisker exploration behaviours in the 5xFAD mouse are affected by sex and retinal degeneration. Genes Brain Behav. 2020 03; 19(3):e12532.
-
Ayyadevara S, Ganne A, Hendrix RD, Balasubramaniam M, Shmookler Reis RJ, Barger SW. Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'. J Neurosci Methods. 2019 05 01; 319:40-46.
-
Lundeen TF, Seibyl JP, Covington MF, Eshghi N, Kuo PH. Signs and Artifacts in Amyloid PET. Radiographics. 2018 Nov-Dec; 38(7):2123-2133.
-
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, Louie G, Kueider-Paisley A, Moseley MA, Thompson JW, St John Williams L, Tenenbaum JD, Blach C, Baillie R, Han X, Bhattacharyya S, Toledo JB, Schafferer S, Klein S, Koal T, Risacher SL, Kling MA, Motsinger-Reif A, Rotroff DM, Jack J, Hankemeier T, Bennett DA, De Jager PL, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, van Duijn CM, Saykin AJ, Kastenm?ller G, Kaddurah-Daouk R. Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome. Alzheimers Dement. 2019 01; 15(1):76-92.
-
Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ. Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2. Sci Rep. 2018 10 05; 8(1):14891.
-
Garvock-de Montbrun T, Fertan E, Stover K, Brown RE. Motor deficits in 16-month-old male and female 3xTg-AD mice. Behav Brain Res. 2019 01 01; 356:305-313.
-
Padala PR, Dennis RA, Padala KP. Addressing Possible Effects of Sleep Apnea in a Study of Methylphenidate for Apathy in Alzheimer's Disease: Response to Kolla and Mansukhani. Am J Psychiatry. 2018 08 01; 175(8):792-793.
-
O'Leary TP, Hussin AT, Gunn RK, Brown RE. Locomotor activity, emotionality, sensori-motor gating, learning and memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease. Brain Res Bull. 2018 06; 140:347-354.
-
Yu H, Harrison FE, Xia F. Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity. Sci Rep. 2018 04 04; 8(1):5600.
-
Scherer RW, Drye L, Mintzer J, Lanct?t K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH. The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial. Trials. 2018 Jan 18; 19(1):46.
-
Garcia-Rill E, Mahaffey S, Hyde JR, Urbano FJ. Bottom-up gamma maintenance in various disorders. Neurobiol Dis. 2019 08; 128:31-39.
-
Padala PR, Padala KP, Lensing SY, Jackson AN, Hunter CR, Parkes CM, Dennis RA, Bopp MM, Caceda R, Mennemeier MS, Roberson PK, Sullivan DH. Repetitive transcranial magnetic stimulation for apathy in mild cognitive impairment: A double-blind, randomized, sham-controlled, cross-over pilot study. Psychiatry Res. 2018 03; 261:312-318.
-
King JL, Wong AA, Brown RE. Age-Related Changes in the Spatial Frequency Threshold of Male and Female 3xTg-AD Mice Using OptoMotry. J Alzheimers Dis. 2018; 62(2):591-596.
-
Morris JK, Piccolo BD, Shankar K, Thyfault JP, Adams SH. The serum metabolomics signature of type 2 diabetes is obscured in Alzheimer's disease. Am J Physiol Endocrinol Metab. 2018 06 01; 314(6):E584-E596.
-
Palmer BW, Harmell AL, Dunn LB, Kim SY, Pinto LL, Golshan S, Jeste DV. Multimedia Aided Consent for Alzheimer's Disease Research. Clin Gerontol. 2018 Jan-Feb; 41(1):20-32.
-
Sonntag KC, Ryu WI, Amirault KM, Healy RA, Siegel AJ, McPhie DL, Forester B, Cohen BM. Late-onset Alzheimer's disease is associated with inherent changes in bioenergetics profiles. Sci Rep. 2017 10 25; 7(1):14038.
-
Lieberman A, Deep A, Shi J, Dhall R, Shafer S, Moguel-Cobos G, Dhillon R, Frames CW, McCauley M. Downward finger displacement distinguishes Parkinson disease dementia from Alzheimer disease. Int J Neurosci. 2018 Feb; 128(2):151-154.
-
Parcon PA, Balasubramaniam M, Ayyadevara S, Jones RA, Liu L, Shmookler Reis RJ, Barger SW, Mrak RE, Griffin WST. Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs. Alzheimers Dement. 2018 02; 14(2):230-242.
-
Jevtic S, Sengar AS, Salter MW, McLaurin J. The role of the immune system in Alzheimer disease: Etiology and treatment. Ageing Res Rev. 2017 Nov; 40:84-94.
-
Padala PR, Padala KP, Lensing SY, Ramirez D, Monga V, Bopp MM, Roberson PK, Dennis RA, Petty F, Sullivan DH, Burke WJ. Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer's Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. Am J Psychiatry. 2018 02 01; 175(2):159-168.
-
Salter MW, Stevens B. Microglia emerge as central players in brain disease. Nat Med. 2017 Sep 08; 23(9):1018-1027.
-
Tchakoute CT, Sainani KL, Henderson VW. Semantic Memory in the Clinical Progression of Alzheimer Disease. Cogn Behav Neurol. 2017 09; 30(3):81-89.
-
Zhang YP, Brown RE, Zhang PC, Zhao YT, Ju XH, Song C. DHA, EPA and their combination at various ratios differently modulated A?25-35-induced neurotoxicity in SH-SY5Y cells. Prostaglandins Leukot Essent Fatty Acids. 2018 09; 136:85-94.
-
Hayes JP, Logue MW, Sadeh N, Spielberg JM, Verfaellie M, Hayes SM, Reagan A, Salat DH, Wolf EJ, McGlinchey RE, Milberg WP, Stone A, Schichman SA, Miller MW. Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain. 2017 03 01; 140(3):813-825.
-
Padala KP, Padala PR, Lensing SY, Dennis RA, Bopp MM, Roberson PK, Sullivan DH. Home-Based Exercise Program Improves Balance and Fear of Falling in Community-Dwelling Older Adults with Mild Alzheimer's Disease: A Pilot Study. J Alzheimers Dis. 2017; 59(2):565-574.
-
Wang W, Moerman-Herzog AM, Slaton A, Barger SW. Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2. Neurobiol Aging. 2017 01; 49:145-153.
-
Adelborg K, Horv?th-Puh? E, Ording A, Pedersen L, S?rensen HT, Henderson VW. Heart failure and risk of dementia: a Danish nationwide population-based cohort study. Eur J Heart Fail. 2017 02; 19(2):253-260.
-
Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
-
Ayyadevara S, Balasubramaniam M, Parcon PA, Barger SW, Griffin WS, Alla R, Tackett AJ, Mackintosh SG, Petricoin E, Zhou W, Shmookler Reis RJ. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell. 2016 10; 15(5):924-39.
-
Palmer BW, Harmell AL, Pinto LL, Dunn LB, Kim SY, Golshan S, Jeste DV. Determinants of Capacity to Consent to Research on Alzheimer's disease. Clin Gerontol. 2017; 40(1):24-34.
-
Roddick KM, Roberts AD, Schellinck HM, Brown RE. Sex and Genotype Differences in Odor Detection in the 3?Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age. Chem Senses. 2016 06; 41(5):433-40.
-
Phillips C, Fahimi A, Das D, Mojabi FS, Ponnusamy R, Salehi A. Noradrenergic System in Down Syndrome and Alzheimer's Disease A Target for Therapy. Curr Alzheimer Res. 2016; 13(1):68-83.
-
Colgan N, Siow B, O'Callaghan JM, Harrison IF, Wells JA, Holmes HE, Ismail O, Richardson S, Alexander DC, Collins EC, Fisher EM, Johnson R, Schwarz AJ, Ahmed Z, O'Neill MJ, Murray TK, Zhang H, Lythgoe MF. Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease. Neuroimage. 2016 Jan 15; 125:739-744.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|