 Cyclic AMP
"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
| Descriptor ID |
D000242
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| MeSH Number(s) |
D03.438.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
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| Concept/Terms |
Cyclic AMP- Cyclic AMP
- AMP, Cyclic
- Adenosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Adenosine
- Adenosine Cyclic Monophosphate
- Cyclic Monophosphate, Adenosine
- Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3,5 Monophosphate
- Adenosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3',5' Monophosphate
- Cyclic 3',5'-Monophosphate, Adenosine
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Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".
This graph shows the total number of publications written about "Cyclic AMP" by people in UAMS Profiles by year, and whether "Cyclic AMP" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2017 | 0 | 2 | 2 | | 2016 | 1 | 2 | 3 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2013 | 0 | 5 | 5 | | 2012 | 0 | 3 | 3 | | 2010 | 1 | 2 | 3 | | 2009 | 0 | 4 | 4 | | 2007 | 1 | 0 | 1 | | 2006 | 0 | 3 | 3 | | 2005 | 1 | 4 | 5 | | 2004 | 0 | 2 | 2 | | 2003 | 1 | 3 | 4 | | 2000 | 1 | 2 | 3 | | 1999 | 2 | 3 | 5 | | 1998 | 2 | 3 | 5 | | 1997 | 1 | 3 | 4 | | 1996 | 1 | 6 | 7 | | 1995 | 2 | 0 | 2 | | 1994 | 1 | 1 | 2 | | 1993 | 0 | 2 | 2 | | 1992 | 2 | 0 | 2 | | 1991 | 1 | 3 | 4 | | 1990 | 0 | 2 | 2 | | 1989 | 2 | 0 | 2 | | 1988 | 1 | 0 | 1 | | 1987 | 0 | 4 | 4 |
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Below are the most recent publications written about "Cyclic AMP" by people in Profiles over the past ten years.
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Jackson-Litteken CD, Ratliff CT, Kneubehl AR, Siletti C, Pack L, Lan R, Huynh TN, Lopez JE, Blevins JS. The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology. Infect Immun. 2021 05 17; 89(6).
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Zhang H, Ramsey A, Xiao Y, Karki U, Xie JY, Xu J, Kelly T, Ono S, Zhou GL. Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion. Mol Cell Biol. 2020 01 30; 40(4).
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Zhao H, Lazarenko OP, Chen JR. Hippuric acid and 3-(3-hydroxyphenyl) propionic acid inhibit murine osteoclastogenesis through RANKL-RANK independent pathway. J Cell Physiol. 2020 01; 235(1):599-610.
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Talpur HS, Worku T, Rehman ZU, Dad R, Bhattarai D, Bano I, Liang A, He C, Yang L. Knockdown of melatonin receptor 1 and induction of follicle-stimulating hormone on the regulation of mouse granulosa cell function. Reprod Biol. 2017 Dec; 17(4):380-388.
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Yang Y, Lei H, Qiang YW, Wang B. Ixazomib enhances parathyroid hormone-induced ß-catenin/T-cell factor signaling by dissociating ß-catenin from the parathyroid hormone receptor. Mol Biol Cell. 2017 Jul 01; 28(13):1792-1803.
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Ford BM, Franks LN, Radominska-Pandya A, Prather PL. Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One. 2016; 11(12):e0167240.
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Luster BR, Urbano FJ, Garcia-Rill E. Intracellular mechanisms modulating gamma band activity in the pedunculopontine nucleus (PPN). Physiol Rep. 2016 Jun; 4(12).
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Sugi T, Ma YF, Tomita T, Murakoshi F, Eaton MS, Yakubu R, Han B, Tu V, Kato K, Kawazu S, Gupta N, Suvorova ES, White MW, Kim K, Weiss LM. Toxoplasma gondii Cyclic AMP-Dependent Protein Kinase Subunit 3 Is Involved in the Switch from Tachyzoite to Bradyzoite Development. mBio. 2016 05 31; 7(3).
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Molden BM, Cooney KA, West K, Van Der Ploeg LH, Baldini G. Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists. Mol Endocrinol. 2015 Nov; 29(11):1619-33.
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Li G, Young KD. A cAMP-independent carbohydrate-driven mechanism inhibits tnaA expression and TnaA enzyme activity in Escherichia coli. Microbiology (Reading). 2014 Sep; 160(Pt 9):2079-2088.
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Peng Y, Deng L, Ding Y, Chen Q, Wu Y, Yang M, Wang Y, Fu Q. Comparative study of somatostatin-human serum albumin fusion proteins and natural somatostatin on receptor binding, internalization and activation. PLoS One. 2014; 9(2):e89932.
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Granell S, Molden BM, Baldini G. Exposure of MC4R to agonist in the endoplasmic reticulum stabilizes an active conformation of the receptor that does not desensitize. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):E4733-42.
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Krishna A, Valderrábano M, Palade PT, Clark JW. Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study. Theor Biol Med Model. 2013 Sep 10; 10:54.
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Henle SJ, Carlstrom LP, Cheever TR, Henley JR. Differential role of PTEN phosphatase in chemotactic growth cone guidance. J Biol Chem. 2013 Jul 19; 288(29):20837-20842.
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Tang T, Lai NC, Wright AT, Gao MH, Lee P, Guo T, Tang R, McCulloch AD, Hammond HK. Adenylyl cyclase 6 deletion increases mortality during sustained ß-adrenergic receptor stimulation. J Mol Cell Cardiol. 2013 Jul; 60:60-7.
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Armaiz-Pena GN, Allen JK, Cruz A, Stone RL, Nick AM, Lin YG, Han LY, Mangala LS, Villares GJ, Vivas-Mejia P, Rodriguez-Aguayo C, Nagaraja AS, Gharpure KM, Wu Z, English RD, Soman KV, Shahzad MM, Shazhad MM, Zigler M, Deavers MT, Zien A, Soldatos TG, Jackson DB, Wiktorowicz JE, Torres-Lugo M, Young T, De Geest K, Gallick GE, Bar-Eli M, Lopez-Berestein G, Cole SW, Lopez GE, Lutgendorf SK, Sood AK. Src activation by ß-adrenoreceptors is a key switch for tumour metastasis. Nat Commun. 2013; 4:1403.
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Granell S, Serra-Juhé C, Martos-Moreno GÁ, Díaz F, Pérez-Jurado LA, Baldini G, Argente J. A novel melanocortin-4 receptor mutation MC4R-P272L associated with severe obesity has increased propensity to be ubiquitinated in the ER in the face of correct folding. PLoS One. 2012; 7(12):e50894.
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Xiang B, Zhang G, Ren H, Sunkara M, Morris AJ, Gartner TK, Smyth SS, Li Z. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism. PLoS One. 2012; 7(12):e51037.
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