Aromatase
"Aromatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
| Descriptor ID |
D001141
|
| MeSH Number(s) |
D08.244.453.915.099 D08.811.682.690.708.170.915.099 D08.811.682.690.708.783.099 D12.776.422.220.453.915.099
|
| Concept/Terms |
Aromatase- Aromatase
- CYP 19
- CYP19
- CYP19 Protein
- Protein, CYP19
- P450AROM
- Cytochrome P-450(AROM)
- Cytochrome P450 19
- Estrogen Synthase
- Estrogen Synthetase
- Androstenedione Aromatase
- Aromatase, Androstenedione
- Cytochrome P-450 CYP19
- Cytochrome P 450 CYP19
|
Below are MeSH descriptors whose meaning is more general than "Aromatase".
Below are MeSH descriptors whose meaning is more specific than "Aromatase".
This graph shows the total number of publications written about "Aromatase" by people in UAMS Profiles by year, and whether "Aromatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aromatase" by people in Profiles over the past ten years.
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Tobacyk J, Brents LK. Response to article - alternative interpretation of "there is reduced immunohistochemical staining of placental aromatase in severe neonatal opioid withdrawal syndrome". J Matern Fetal Neonatal Med. 2023 12; 36(1):2183469.
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Starlard-Davenport A, Orloff MS, Dhakal I, Penney RB, Kadlubar SA. Genotypic and allelic variability in CYP19A1 among populations of African and European ancestry. PLoS One. 2015; 10(2):e0117347.