Item Type | Name |
Academic Article
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Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers.
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Academic Article
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Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.
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Concept
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Contractile Proteins
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Concept
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Calcium-Binding Proteins
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Concept
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Microtubule-Associated Proteins
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Concept
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Carrier Proteins
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Concept
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Fungal Proteins
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Concept
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Cytoskeletal Proteins
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Concept
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Microtubule Proteins
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Concept
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Eye Proteins
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Concept
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DNA-Binding Proteins
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Concept
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Membrane Proteins
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Concept
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Oncogene Proteins, Viral
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Concept
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Luminescent Proteins
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Concept
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Proteins
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Concept
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Proto-Oncogene Proteins
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Concept
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Repressor Proteins
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Concept
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Oncogene Proteins
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Concept
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GTP-Binding Proteins
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Concept
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Proto-Oncogene Proteins c-raf
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Concept
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Recombinant Proteins
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Concept
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Proto-Oncogene Proteins c-fos
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Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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Homeodomain Proteins
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Concept
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Proto-Oncogene Proteins B-raf
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Concept
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Monomeric GTP-Binding Proteins
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Concept
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HSP70 Heat-Shock Proteins
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Concept
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Proto-Oncogene Proteins c-jun
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Wnt Proteins
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Concept
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Apoptosis Regulatory Proteins
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Concept
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Immediate-Early Proteins
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Concept
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Viral Proteins
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Concept
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Smad Proteins
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Concept
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Green Fluorescent Proteins
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Concept
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Proto-Oncogene Proteins c-mdm2
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Concept
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Proto-Oncogene Proteins c-myb
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Concept
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5-Lipoxygenase-Activating Proteins
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Concept
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Saccharomyces cerevisiae Proteins
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Concept
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LIM-Homeodomain Proteins
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Concept
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Heat-Shock Proteins
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Concept
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RNA-Binding Proteins
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Concept
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Extracellular Matrix Proteins
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Concept
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ras Proteins
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Concept
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Tumor Suppressor Proteins
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Retroviridae Proteins, Oncogenic
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Concept
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Oncogene Proteins v-mos
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Concept
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Cell Cycle Proteins
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Proto-Oncogene Proteins c-kit
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Concept
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CCAAT-Enhancer-Binding Proteins
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Concept
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Papillomavirus E7 Proteins
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Concept
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GABA Plasma Membrane Transport Proteins
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Concept
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Proto-Oncogene Proteins c-met
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Concept
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Neoplasm Proteins
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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LIM Domain Proteins
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Concept
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Hedgehog Proteins
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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GPI-Linked Proteins
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Concept
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Nuclear Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Oncogene Proteins v-raf
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Concept
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Telomere-Binding Proteins
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Academic Article
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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
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Academic Article
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Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.
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Academic Article
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p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
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Academic Article
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Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.
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Academic Article
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Ascites analysis by a microfluidic chip allows tumor-cell profiling.
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Academic Article
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Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.
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Academic Article
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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
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Academic Article
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ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.
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Academic Article
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Calcineurin activates cytoglobin transcription in hypoxic myocytes.
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Academic Article
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A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.
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Academic Article
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NORE1A tumor suppressor candidate modulates p21CIP1 via p53.
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Academic Article
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Novel therapeutic targets.
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Academic Article
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Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
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Academic Article
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An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.
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Academic Article
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Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
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Academic Article
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A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.
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Academic Article
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EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
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Academic Article
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Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study.
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Academic Article
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Efficacy and safety of imatinib mesylate (Gleevec) and immunohistochemical expression of c-Kit and PDGFR-beta in a Gynecologic Oncology Group Phase Il Trial in women with recurrent or persistent carcinosarcomas of the uterus.
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Academic Article
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Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.
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Academic Article
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Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth.
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Academic Article
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AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets.
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Academic Article
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TGF-? modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment.
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Academic Article
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Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array.
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Academic Article
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Overexpression of CEACAM6 in borderline and invasive mucinous ovarian neoplasms.
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Academic Article
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Cyclooxygenase-2 expression predicts recurrence of cervical dysplasia following loop electrosurgical excision procedure.
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Academic Article
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Spleen Tyrosine Kinase Confers Paclitaxel Resistance in Ovarian Cancer.
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Academic Article
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Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles.
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Academic Article
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Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
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Academic Article
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Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses.
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Academic Article
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Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.
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Academic Article
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The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.
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Academic Article
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Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.
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Academic Article
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Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.
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Academic Article
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Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.
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Academic Article
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Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
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Academic Article
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Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
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Academic Article
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The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.
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Academic Article
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Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer.
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Academic Article
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RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential.
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Academic Article
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Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
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Academic Article
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Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study.
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Academic Article
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CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential.
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Academic Article
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Common variation in Nemo-like kinase is associated with risk of ovarian cancer.
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Academic Article
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Pre-treatment tumor expression of ERCC1 in women with advanced stage epithelial ovarian cancer is not predictive of clinical outcomes: a Gynecologic Oncology Group study.
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Academic Article
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Ovarian cancer risk associated with inherited inflammation-related variants.
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Academic Article
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Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.
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Academic Article
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Ovarian cancer: not a borderline issue!
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Academic Article
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CD157 in ovarian carcinoma: how does it help us?
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Academic Article
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SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK.
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Academic Article
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Clinicopathological analysis of c-kit expression in carcinosarcomas and leiomyosarcomas of the uterine corpus.
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Academic Article
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A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
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Academic Article
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Common variants at 19p13 are associated with susceptibility to ovarian cancer.
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Academic Article
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Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.
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Academic Article
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The origin of ovarian cancer?is it getting clearer?
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Academic Article
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ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
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Academic Article
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AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
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Academic Article
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HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
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Academic Article
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Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression.
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Academic Article
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Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
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Academic Article
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The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer.
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Academic Article
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Reactive oxygen species mediated apoptosis of esophageal cancer cells induced by marine triprenyl toluquinones and toluhydroquinones.
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Academic Article
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A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.
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Academic Article
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LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.
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Academic Article
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Phase 1 Study of Monotherapy with KHK2866, an Anti-Heparin-Binding Epidermal Growth Factor-Like Growth Factor Monoclonal Antibody, in Patients with Advanced Cancer.
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Academic Article
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Activator protein-1 contributes to high NaCl-induced increase in tonicity-responsive enhancer/osmotic response element-binding protein transactivating activity.
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Academic Article
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Cell cycle and related protein.
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Grant
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OVARIAN CANCER DETECTION BY UTERINE LAVAGE DNA AND SERUM PROTEINS: A PHASE 2 BIOMARKER STUDY
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Grant
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The FGF18/FGFR4 amplicon: Novel therapeutic biomarkers for ovarian cancer
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Grant
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Proteogenomic studies aimed at understanding ovarian tumor responses to agents targeting the DNA damage response and translating this knowledge into clinical benefit
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Academic Article
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Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells.
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Academic Article
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Regions within the c-Myc protein that are necessary for transformation are also required for inhibition of differentiation of murine erythroleukemia cells.
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Academic Article
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A complex pattern of translational initiation and phosphorylation in L-myc proteins.
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Academic Article
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The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells.
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Academic Article
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L-myc cooperates with ras to transform primary rat embryo fibroblasts.
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Academic Article
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Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
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Academic Article
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Characterization of measles polypeptides by monoclonal antibodies.
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Academic Article
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Early events in the neoplastic transformation of respiratory epithelium.
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Academic Article
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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
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Academic Article
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The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation.
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Academic Article
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Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer.
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Academic Article
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p53: a frequent target for genetic abnormalities in lung cancer.
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Academic Article
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A transfected L-myc gene can substitute for c-myc in blocking murine erythroleukemia differentiation.
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Academic Article
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The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.
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Academic Article
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Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
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Academic Article
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Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.
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Academic Article
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Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.
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Academic Article
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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
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Academic Article
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Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
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Academic Article
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Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C.
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Academic Article
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The inhibitory activity of a transdominant c-jun mutant fused to the ligand binding domain of the estrogen receptor.
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Academic Article
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Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
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Academic Article
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PACAP stimulates c-fos mRNAs in small cell lung cancer cells.
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Academic Article
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Regulation of nuclear oncogenes expressed in lung cancer cell lines.
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Academic Article
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Molecular characterization of adenocarcinoma of the cervix.
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Academic Article
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AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells.
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Academic Article
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RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
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Academic Article
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JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells.
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Academic Article
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Abnormal Fhit expression in malignant and premalignant lesions of the cervix.
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Academic Article
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cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
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Academic Article
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Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun.
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Academic Article
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c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
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Academic Article
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Bombesin stimulates c-fos and c-jun mRNAs in small cell lung cancer cells.
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Academic Article
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Mechanism of action of a dominant-negative mutant of c-Jun.
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Academic Article
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Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.
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Academic Article
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Cooperation between retinoic acid and phorbol esters enhances human teratocarcinoma differentiation.
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Academic Article
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Altered cJUN expression: an early event in human lung carcinogenesis.
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Academic Article
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Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
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Academic Article
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Activation and inhibition of the AP-1 complex in human breast cancer cells.
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Academic Article
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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
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Academic Article
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The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
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Academic Article
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Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
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Academic Article
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Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas.
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Academic Article
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FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
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Academic Article
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Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells.
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Academic Article
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Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells.
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Academic Article
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The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.
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Academic Article
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Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.
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Academic Article
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Identification of domains of c-Jun mediating androgen receptor transactivation.
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Academic Article
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Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
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Academic Article
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Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).
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Academic Article
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Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.
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Academic Article
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p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
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Academic Article
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Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and a contrasting decrease in p27(Kip1).
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Academic Article
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Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint.
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Academic Article
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c-Jun triggers apoptosis in human vascular endothelial cells.
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Academic Article
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TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta.
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Academic Article
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Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis.
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Academic Article
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Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
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Academic Article
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c-Jun activation-dependent tumorigenic transformation induced paradoxically by overexpression or block of S-adenosylmethionine decarboxylase.
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Academic Article
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The role of p27 in endometrial carcinoma.
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Academic Article
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N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines.
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Academic Article
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RASSF6 is a novel member of the RASSF family of tumor suppressors.
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Academic Article
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Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant.
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Academic Article
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Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells.
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Academic Article
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Identification of LMX1B as a novel oncogene in human ovarian cancer.
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Academic Article
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Phase I study of safety and pharmacokinetics of the anti-MUC16 antibody-drug conjugate DMUC5754A in patients with platinum-resistant ovarian cancer or unresectable pancreatic cancer.
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Academic Article
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Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.
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Academic Article
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LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma.
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Academic Article
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DKK1 is a predictive biomarker for response to DKN-01: Results of a phase 2 basket study in women with recurrent endometrial carcinoma.
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