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Search Results to Michael Birrer

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One or more keywords matched the following items that are connected to Birrer, Michael

Item TypeName
Academic Article Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.
Concept Epidermal Growth Factor
Concept Hepatocyte Growth Factor
Concept Transforming Growth Factor beta
Concept Receptors, Fibroblast Growth Factor
Concept Fibroblast Growth Factor 1
Concept Transcription Factor AP-1
Concept Receptors, Vascular Endothelial Growth Factor
Concept Transcription Factor RelB
Concept Receptors, Transforming Growth Factor beta
Concept Atrial Natriuretic Factor
Concept Receptor, Fibroblast Growth Factor, Type 4
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Concept Connective Tissue Growth Factor
Concept Tumor Necrosis Factor-alpha
Concept Vascular Endothelial Growth Factor Receptor-2
Concept STAT3 Transcription Factor
Concept Transforming Growth Factor beta1
Concept Receptor, Fibroblast Growth Factor, Type 2
Concept GATA1 Transcription Factor
Concept Vascular Endothelial Growth Factor A
Concept Transcription Factor RelA
Concept Receptor, Platelet-Derived Growth Factor beta
Concept Transcription Factor CHOP
Academic Article p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
Academic Article Inhibition of AP-1 transcriptional activity blocks the migration, invasion, and experimental metastasis of murine osteosarcoma.
Academic Article A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.
Academic Article Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Academic Article A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.
Academic Article EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Academic Article Overexpression of elafin in ovarian carcinoma is driven by genomic gains and activation of the nuclear factor kappaB pathway and is associated with poor overall survival.
Academic Article Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas.
Academic Article Efficacy and safety of imatinib mesylate (Gleevec) and immunohistochemical expression of c-Kit and PDGFR-beta in a Gynecologic Oncology Group Phase Il Trial in women with recurrent or persistent carcinosarcomas of the uterus.
Academic Article Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.
Academic Article Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer.
Academic Article AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets.
Academic Article TGF-? modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment.
Academic Article Restoration of an impaired TGF-beta1 autocrine growth-inhibitory circuit results in growth inhibition of ovarian epithelial cancer cells and complete inhibition of their tumorigenicity.
Academic Article Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses.
Academic Article Phase II study of cisplatin plus cetuximab in advanced, recurrent, and previously treated cancers of the cervix and evaluation of epidermal growth factor receptor immunohistochemical expression: a Gynecologic Oncology Group study.
Academic Article IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.
Academic Article Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.
Academic Article Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer.
Academic Article Inflammatory cytokine tumor necrosis factor alpha confers precancerous phenotype in an organoid model of normal human ovarian surface epithelial cells.
Academic Article FGFR2 mutations are rare across histologic subtypes of ovarian cancer.
Academic Article Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.
Academic Article Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer.
Academic Article MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
Academic Article Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancer.
Academic Article AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Academic Article HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
Academic Article Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression.
Academic Article Review: Targeting the Transforming Growth Factor-Beta Pathway in Ovarian Cancer.
Academic Article Phase 1 Study of Monotherapy with KHK2866, an Anti-Heparin-Binding Epidermal Growth Factor-Like Growth Factor Monoclonal Antibody, in Patients with Advanced Cancer.
Academic Article Activator protein-1 contributes to high NaCl-induced increase in tonicity-responsive enhancer/osmotic response element-binding protein transactivating activity.
Academic Article A Phase 1 trial of the poly(ADP-ribose) polymerase inhibitor olaparib (AZD2281) in combination with the anti-angiogenic cediranib (AZD2171) in recurrent epithelial ovarian or triple-negative breast cancer.
Academic Article p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts.
Grant The FGF18/FGFR4 amplicon: Novel therapeutic biomarkers for ovarian cancer
Grant The Molecular Genetics of Gynecologic Cancers
Academic Article Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.
Academic Article Expression of the atrial natriuretic factor gene in small cell lung cancer tumors and tumor cell lines.
Academic Article Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Academic Article The inhibitory activity of a transdominant c-jun mutant fused to the ligand binding domain of the estrogen receptor.
Academic Article AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells.
Academic Article RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
Academic Article JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells.
Academic Article cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
Academic Article Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun.
Academic Article c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
Academic Article Altered cJUN expression: an early event in human lung carcinogenesis.
Academic Article Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
Academic Article Activation and inhibition of the AP-1 complex in human breast cancer cells.
Academic Article Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
Academic Article The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
Academic Article Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
Academic Article Breast cancer cells have lower activating protein 1 transcription factor activity than normal mammary epithelial cells.
Academic Article Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells.
Academic Article Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells.
Academic Article The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.
Academic Article Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.
Academic Article Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.
Academic Article Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and a contrasting decrease in p27(Kip1).
Academic Article TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta.
Academic Article Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
Academic Article N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines.
Academic Article Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant.
Academic Article Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells.
Academic Article Immune Activation in Patients with Locally Advanced Cervical Cancer Treated with Ipilimumab Following Definitive Chemoradiation (GOG-9929).
Academic Article Neutralization of TGF? Improves Tumor Immunity and Reduces Tumor Progression in Ovarian Carcinoma.
Academic Article Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.

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