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Search Results to Peter Crooks

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One or more keywords matched the following items that are connected to Crooks, Peter

Item TypeName
Concept Bacterial Proteins
Concept Carrier Proteins
Concept Cytoskeletal Proteins
Concept DNA-Binding Proteins
Concept Membrane Proteins
Concept Proteins
Concept Proto-Oncogene Proteins
Concept GTP-Binding Proteins
Concept Recombinant Proteins
Concept Proto-Oncogene Proteins p21(ras)
Concept Vesicular Monoamine Transport Proteins
Concept Mitochondrial Proteins
Concept Vesicular Biogenic Amine Transport Proteins
Concept Serotonin Plasma Membrane Transport Proteins
Concept Apoptosis Regulatory Proteins
Concept Plasma Membrane Neurotransmitter Transport Proteins
Concept Neurotransmitter Transport Proteins
Concept Mutant Chimeric Proteins
Concept Nerve Tissue Proteins
Concept Norepinephrine Plasma Membrane Transport Proteins
Concept Viral Nonstructural Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept I-kappa B Proteins
Concept Membrane Transport Proteins
Concept Dopamine Plasma Membrane Transport Proteins
Concept Neoplasm Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-akt
Concept Nuclear Proteins
Concept Recombinant Fusion Proteins
Academic Article Novel chemical enhancers of heat shock increase thermal radiosensitization through a mitotic catastrophe pathway.
Academic Article Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier.
Academic Article NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols.
Academic Article meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.
Academic Article The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins.
Academic Article Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras.
Academic Article Spectrophotometric and steady-state kinetic analysis of the biosynthetic arginine decarboxylase of Yersinia pestis utilizing arginine analogues as inhibitors and alternative substrates.
Academic Article Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters.
Academic Article Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood-brain barrier choline transporter.
Academic Article Bis-azaaromatic quaternary ammonium salts as ligands for the blood-brain barrier choline transporter.
Academic Article 3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood-brain barrier choline transporter.
Academic Article N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.
Academic Article The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery.
Academic Article Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.
Academic Article Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature.
Academic Article Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter.
Academic Article The novel chemical entity YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppressing repair of DNA double-strand breaks and enhancing radiosensitization.
Academic Article The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.
Academic Article Synthesis of novel isoluminol probes and their use in rapid bacterial assays.
Academic Article Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake.
Academic Article Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2.
Academic Article Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.
Academic Article Vesicular monoamine transporter 2: role as a novel target for drug development.
Academic Article Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.
Academic Article Quinlobelane: a water-soluble lobelane analogue and inhibitor of VMAT2.
Academic Article Phenyl ring-substituted lobelane analogs: inhibition of [³H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.
Academic Article The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN.
Academic Article Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation.
Academic Article Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse.
Academic Article Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.
Academic Article Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.
Academic Article bis-Pyridinium cyclophanes: novel ligands with high affinity for the blood-brain barrier choline transporter.
Academic Article The effect of VMAT2 inhibitor GZ-793A on the reinstatement of methamphetamine-seeking in rats.
Academic Article Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues.
Academic Article KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells.
Academic Article Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats.
Academic Article Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.
Academic Article The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.
Academic Article GZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine.
Academic Article Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2).
Academic Article Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2.
Academic Article The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
Academic Article Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo.
Academic Article Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2).
Academic Article Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.
Academic Article Development and validation of a novel assay to identify radiosensitizers that target nucleophosmin 1.
Academic Article 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1).
Academic Article 1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.
Academic Article Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article Synthesis and in vitro evaluation of water-soluble 1,4-diphenethylpiperazine analogs as novel inhibitors of the vesicular monoamine transporter-2.
Academic Article Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors.
Academic Article Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.
Academic Article Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo.
Academic Article Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues.
Academic Article Lobeline displaces [3H]dihydrotetrabenazine binding and releases [3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine.
Academic Article A unique interaction between polyamine and multidrug resistance (P-glycoprotein) transporters in cultured Chinese hamster ovary cells transfected with mouse mdr-1 gene.
Academic Article NF-?B-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT.
Academic Article Efficacy of dimethylaminoparthenolide and sulindac in combination with gemcitabine in a genetically engineered mouse model of pancreatic cancer.
Academic Article GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2.
Academic Article Succinamide derivatives of melampomagnolide B and their anti-cancer activities.
Academic Article Persistent Activation of NF-?B in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.
Academic Article Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development.
Academic Article DMAPT inhibits NF-?B activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivo.
Academic Article Fluoroethoxy-1,4-diphenethylpiperidine and piperazine derivatives: Potent and selective inhibitors of [3H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article New Scaffold for Lead Compounds to Treat Methamphetamine Use Disorders.
Academic Article Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats.
Academic Article N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3.
Grant Early Events in Alzheimer Pathogenesis
Academic Article GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine.
Academic Article Targeting NPM1 in irradiated cells inhibits NPM1 binding to RAD51, RAD51 foci formation and radiosensitizes NSCLC.
Academic Article Taking the sub Q route in anemia management.

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