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Search Results to John Imig

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One or more keywords matched the following items that are connected to Imig, John

Item TypeName
Concept Rats, Inbred SHR
Concept Rats, Inbred BN
Concept Rats, Inbred Strains
Concept Rats, Zucker
Concept Rats, Inbred F344
Concept Rats, Sprague-Dawley
Concept Rats, Wistar
Concept Rats
Concept Rats, Inbred Dahl
Concept Rats, Inbred WKY
Concept Rats, Transgenic
Academic Article Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats.
Academic Article Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome.
Academic Article Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats.
Academic Article Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells.
Academic Article Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension.
Academic Article Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats.
Academic Article Protein phosphatase 2A and Ca2+-activated K+ channels contribute to 11,12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation.
Academic Article Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Academic Article ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin.
Academic Article Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles.
Academic Article Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.
Academic Article Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats.
Academic Article Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
Academic Article Role of the cytochrome P-450/ epoxyeicosatrienoic acids pathway in the pathogenesis of renal dysfunction in cirrhosis.
Academic Article Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats.
Academic Article Cytochrome P450 epoxygenases provide a novel mechanism for penile erection.
Academic Article Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension.
Academic Article Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Academic Article Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease.
Academic Article Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats.
Academic Article Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.
Academic Article Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats.
Academic Article Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.
Academic Article Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension.
Academic Article The roles of intrarenal 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of renal function in hypertensive Ren-2 transgenic rats.
Academic Article Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels.
Academic Article Renal AT1 receptor protein expression during the early stage of diabetes mellitus.
Academic Article Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats.
Academic Article 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries.
Academic Article Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Academic Article TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats.
Academic Article Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib.
Academic Article Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
Academic Article Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
Academic Article Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats.
Academic Article 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Academic Article Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats.
Academic Article Infarct size-limiting effect of epoxyeicosatrienoic acid analog EET-B is mediated by hypoxia-inducible factor-1a via downregulation of prolyl hydroxylase 3.
Academic Article Radiation-induced afferent arteriolar endothelial-dependent dysfunction involves decreased epoxygenase metabolites.
Academic Article Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.
Academic Article Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids.
Academic Article Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.
Academic Article Epoxyeicosatrienoic acids, hypertension, and kidney injury.
Academic Article p66Shc regulates renal vascular tone in hypertension-induced nephropathy.
Academic Article Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Academic Article A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat.
Academic Article Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart.
Academic Article Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure.
Academic Article Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.
Academic Article Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor ? agonist improve vascular function and decrease renal injury in hypertensive obese rats.
Academic Article Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet.
Academic Article Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.
Academic Article Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.
Academic Article Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats.
Academic Article Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.
Academic Article Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats.
Academic Article Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors.
Academic Article Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension.
Academic Article 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels.
Academic Article Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension.
Academic Article Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension.
Academic Article Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat.
Academic Article Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.
Academic Article Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Academic Article The epoxyeicosatrienoic acid analog PVPA ameliorates cyclosporine-induced hypertension and renal injury in rats.
Academic Article Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet.
Academic Article Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats.
Academic Article Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases.
Academic Article Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.
Academic Article Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries.
Academic Article Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture.
Academic Article Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy.
Academic Article Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II.
Academic Article Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Academic Article Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats.
Academic Article Rofecoxib decreases renal injury in obese Zucker rats.
Academic Article P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid.
Academic Article Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.
Academic Article 20-hydroxyeicosatetraenoic acid and angiotensin: a positive feedback system to cause hypertension.
Academic Article Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.
Academic Article Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity.
Academic Article Azilsartan decreases renal and cardiovascular injury in the spontaneously hypertensive obese rat.
Academic Article Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Academic Article Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.
Academic Article Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade.
Academic Article Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension.
Academic Article Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior.
Academic Article Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.
Academic Article An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension.
Academic Article An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats.
Academic Article Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats.
Academic Article Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores.
Academic Article Age-related alterations in NOS and oxidative stress in mesenteric arteries from male and female rats.
Academic Article Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Academic Article PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats.
Academic Article Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.
Academic Article Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.
Academic Article Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats.
Academic Article L-type calcium channels in the renal microcirculatory response to endothelin.
Academic Article Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.
Academic Article A novel dual PPAR-? agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes.
Grant OXYGENASE METABOLITES AND RENAL VASCULAR ACTIVITY
Grant Novel epoxide hydrolase inhibitor for stroke prevention

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