Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

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Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD. Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clin Sci (Lond). 2009 Jan; 116(1):61-70.

View in: PubMed

subject areas

Adamantane
Animals
Antihypertensive Agents
Blood Glucose
Diabetes Mellitus, Experimental
Diabetes Mellitus, Type 2
Diabetic Nephropathies
Disease Progression
Drug Evaluation, Preclinical
Enzyme Inhibitors
Epoxide Hydrolases
Hypertension
Insulin
Lauric Acids
Lipids
Male
NF-kappa B
Rats
Rats, Inbred Strains

authors with profiles

John Imig