Liver Failure, Acute
"Liver Failure, Acute" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Descriptor ID |
D017114
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MeSH Number(s) |
C06.552.308.500.750
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Concept/Terms |
Liver Failure, Acute- Liver Failure, Acute
- Failure, Acute Liver
- Fulminating Hepatic Failure
- Fulminating Hepatic Failures
- Hepatic Failure, Fulminating
- Hepatic Failures, Fulminating
- Liver Failure, Fulminant
- Fulminant Liver Failure
- Fulminant Liver Failures
- Liver Failures, Fulminant
- Hepatic Failure, Acute
- Acute Hepatic Failure
- Failure, Acute Hepatic
- Hepatic Failure, Fulminant
- Fulminant Hepatic Failure
- Fulminant Hepatic Failures
- Hepatic Failures, Fulminant
- Acute Liver Failure
- Fulminating Liver Failure
- Fulminating Liver Failures
- Liver Failure, Fulminating
- Liver Failures, Fulminating
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Below are MeSH descriptors whose meaning is more general than "Liver Failure, Acute".
Below are MeSH descriptors whose meaning is more specific than "Liver Failure, Acute".
This graph shows the total number of publications written about "Liver Failure, Acute" by people in UAMS Profiles by year, and whether "Liver Failure, Acute" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 1 | 0 | 1 | 2023 | 1 | 0 | 1 | 2022 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 | 2019 | 2 | 0 | 2 | 2018 | 1 | 0 | 1 | 2016 | 1 | 1 | 2 | 2015 | 2 | 1 | 3 | 2014 | 2 | 0 | 2 | 2013 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2011 | 3 | 0 | 3 | 2010 | 1 | 1 | 2 | 2009 | 1 | 0 | 1 | 2007 | 1 | 0 | 1 | 2006 | 7 | 0 | 7 | 2004 | 2 | 0 | 2 | 2003 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Liver Failure, Acute" by people in Profiles over the past ten years.
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Rule JA, Ajayi F, James LP, Tujios SR, Sussman NL, Rakela JL, Ganger D, Bass NL, Reuben A, Stravitz RT, Lee WM. Differentiating Ischemic Hepatitis from Acetaminophen Overdose in Acute Liver Failure: Role of Acetaminophen Adducts-Ischemic Hepatitis vs Acetaminophen Overdose. Dig Dis Sci. 2024 Oct; 69(10):3952-3961.
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Price JR, Hagrass H, Filip AB, McGill MR. LDH and the MELD-LDH in Severe Acute Liver Injury and Acute Liver Failure: Preliminary Confirmation of a Novel Prognostic Score for Risk Stratification. J Appl Lab Med. 2023 05 04; 8(3):504-513.
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Vazquez JH, Kennon-McGill S, Byrum SD, Mackintosh SG, Jaeschke H, Williams DK, Lee WM, Dranoff JA, McGill MR. Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways. Toxicol Sci. 2022 04 26; 187(1):25-34.
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Sharma R, Kapoor N, Chaudhari KS, Scofield RH. Reversible Fulminant Hepatitis Secondary to Cocaine in the Setting of ?-Blocker Use. J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709620924203.
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Win S, Min RW, Chen CQ, Zhang J, Chen Y, Li M, Suzuki A, Abdelmalek MF, Wang Y, Aghajan M, Aung FW, Diehl AM, Davis RJ, Than TA, Kaplowitz N. Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury. J Clin Invest. 2019 12 02; 129(12):5278-5293.
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Khanal T, Leung YK, Jiang W, Timchenko N, Ho SM, Kim K. NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries. FASEB J. 2019 07; 33(7):8335-8348.
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Ganger DR, Rule J, Rakela J, Bass N, Reuben A, Stravitz RT, Sussman N, Larson AM, James L, Chiu C, Lee WM. Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality. Am J Gastroenterol. 2018 09; 113(9):1319.
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Bhushan B, Chavan H, Borude P, Xie Y, Du K, McGill MR, Lebofsky M, Jaeschke H, Krishnamurthy P, Apte U. Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice. Toxicol Sci. 2017 02; 155(2):363-378.
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Roberts DW, Lee WM, Hinson JA, Bai S, Swearingen CJ, Stravitz RT, Reuben A, Letzig L, Simpson PM, Rule J, Fontana RJ, Ganger D, Reddy KR, Liou I, Fix O, James LP. An Immunoassay to Rapidly Measure Acetaminophen Protein?Adducts Accurately Identifies Patients With Acute Liver?Injury or Failure. Clin Gastroenterol Hepatol. 2017 Apr; 15(4):555-562.e3.
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McGill MR, Du K, Weemhoff JL, Jaeschke H. Critical review of resveratrol in xenobiotic-induced hepatotoxicity. Food Chem Toxicol. 2015 Dec; 86:309-18.
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Guldiken N, Zhou Q, Kucukoglu O, Rehm M, Levada K, Gross A, Kwan R, James LP, Trautwein C, Omary MB, Strnad P. Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation. Hepatology. 2015 Sep; 62(3):876-86.
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Alonso EM, James LP, Zhang S, Squires RH. Acetaminophen Adducts Detected in Serum of Pediatric Patients With Acute Liver Failure. J Pediatr Gastroenterol Nutr. 2015 Jul; 61(1):102-7.
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