Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke.

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Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke.

Ishrat T, Fouda AY, Pillai B, Eldahshan W, Ahmed H, Waller JL, Ergul A, Fagan SC. Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke. J Cereb Blood Flow Metab. 2019 08; 39(8):1635-1647.

View in: PubMed

subject areas

Animals
Behavior, Animal
Disease Models, Animal
Fibrinolytic Agents
Male
Random Allocation
Rats
Rats, Wistar
Recovery of Function
Stroke
Sulfonamides
Thiophenes
Thromboembolism
Tissue Plasminogen Activator

authors with profiles

Abdelrahman Fouda