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@uada.edu
@ualr.edu
@uapb.edu
@uark.edu
University of Arkansas for Medical Sciences
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Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.
Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC. Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. Circulation. 2004 Mar 16; 109(10):1299-306.
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PubMed
subject areas
Androstadienes
Animals
Aorta
Carotid Artery Injuries
Catheterization
Cell Division
Cells, Cultured
Chromones
Culture Media, Serum-Free
Enzyme Inhibitors
Morpholines
Muscle, Smooth, Vascular
Myocytes, Smooth Muscle
Oligonucleotides, Antisense
Phenotype
Phosphatidylinositol 3-Kinases
Phosphorylation
Protein Kinase Inhibitors
Protein Kinases
Protein Processing, Post-Translational
Protein Tyrosine Phosphatases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
PTEN Phosphohydrolase
Rats
Rats, Sprague-Dawley
Ribosomal Protein S6
Ribosomal Protein S6 Kinases, 70-kDa
Signal Transduction
Sirolimus
TOR Serine-Threonine Kinases
Tunica Intima
authors with profiles
Peter Mourani