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Peter Mourani

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Critical Care
Address1120 Marshall Street
Mail Slot # 842
Little Rock AR 72202
Phone501-364-7373
ORCID ORCID Icon0000-0002-1829-3775 Additional info
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    Other Roles
    President, Arkansas Children's Research Institute

    Collapse Overview 

    Collapse Affiliation 
    Collapse member of
    American Thoracic Society
    Society of Critical Care Medicine
    Society of Pediatric Research
    Collapse clinical activities
    Pediatric Critical Care

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    President, Arkansas Children's research Institute

    Collapse education and training
    University of Notre Dame, Notre Dame, INBS05/1990Pre-professional studies
    Loyola University Stritch School of Medicine, Maywood, ILMD06/1994Medicine
    University of Colorado Health Sciences Center, Denver, CO10/2001Pediatric Critical Care
    University of Colorado Health Sciences Center, Denver, CO10/2001Pediatric Pulmonary Medicine
    Loyola University Medical Center, Maywood, IL06/1997Pediatrics

    Collapse Research 
    Collapse research overview
    My overall research focus has been the identification of mechanisms and biomarkers of acute lung disease in critically ill neonates, infants, and children. Specifically, I have had two research foci: 1) Developmental lung and lung vascular disease in infants who are born extremely premature; and 2) Lower respiratory tract infections, including ventilator-associated-pneumonia in critically ill children requiring mechanical ventilator support. While seemingly disparate topics, these two foci have capitalized on the breadth of my training as both a pulmonologist and critical care physician and collaboration with multi-disciplinary scientific teams to obtain a consistent level of funded projects (including NIH R and U mechanisms) and produce impactful results. In addition to serving as principal investigator (PI) for funded projects in these focused areas, I serve as the site PI and Steering Committee member for the prestigious NICHD supported Collaborative Pediatric Critical Care Research Network (CPCCRN), which performs meaningful clinical research in the field of pediatric critical illness and injury. I am a key member of the team that designed the Personalized Immunomodulation in Pediatric Sepsis-induced MODS (PRECISE) for the upcoming cycle of CPCCRN, which will be among the first personalized medicine trials in pediatric critical care.

    Collapse research activities and funding
    CC035765     (MOURANI, PETER)Jul 1, 2022 - Jun 30, 2023
    UAMS ACHRI Flow Through
    ACRI Strategic Plan & Other
    Role: Principal Investigator
    GR034138     (MOURANI, PETER)Dec 1, 2021 - Nov 30, 2022
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: UAMS ACHRI Flow Through
    GR034138 Mourani ACRI-Integrated Host/Microbe Metagenomics to Improve Lower Respiratory Tract Infection Diagnosis in Critically Ill Children
    Role: Principal Investigator
    RL1HD107775     (NOZIK, EVA S.)Aug 18, 2021 - Jul 31, 2026
    NIH
    Collaborative Pediatric Critical Care Research Network - Clinical Site
    Role: Principal Investigator
    R01HL155418     (LANGELIER, CHARLES)Feb 1, 2021 - Nov 30, 2024
    NIH
    Integrated Host/Microbe Metagenomics to Improve Lower Respiratory Tract Infection Diagnosis in Critically Ill Children
    Role: Co-Investigator
    R01HL145679     (TEPPER, ROBERT S.)Mar 1, 2019 - Feb 28, 2023
    NIH
    Physiological Phenotyping of Respiratory Outcomes in Infants Born Premature
    Role: Co-Investigator
    UG1HD083171     (MOURANI, PETER M)Dec 24, 2014 - Nov 30, 2020
    NIH
    Collaborative Network Study of Airway Microbiome and Host Responses in Pediatric Respiratory Failure
    Role: Principal Investigator
    R01HL124103     (MOURANI, PETER M)Sep 1, 2014 - May 31, 2019
    NIH
    The Microbiome, Virome and Host Responses Preceding Ventilator-Associated Pneumon
    Role: Principal Investigator
    R01HL085703     (ABMAN, STEVEN HERBERT)Apr 1, 2008 - Jun 30, 2014
    NIH
    Genetic Basis for Impaired Angiogenic Signaling in BPD
    Role: Co-Investigator
    K23RR021921     (MOURANI, PETER M)Aug 16, 2005 - Jul 31, 2011
    NIH
    Pathogenetic Mechanisms of Brochopulmonary Dysplasia
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Frazier AH, Topjian AA, Reeder RW, Morgan RW, Fink EL, Franzon D, Graham K, Harding ML, Mourani PM, Nadkarni VM, Wolfe HA, Ahmed T, Bell MJ, Burns C, Carcillo JA, Carpenter TC, Diddle JW, Federman M, Friess SH, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Meert KL, Naim MY, Notterman D, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Yates AR, Sutton RM, Berg RA. Association of Pediatric Post-Cardiac Arrest Ventilation and Oxygenation with Survival Outcomes. Ann Am Thorac Soc. 2024 Mar 20. PMID: 38507645.
      View in: PubMed
    2. Ames SG, Maddux AB, Burgunder L, Meeks H, Fink EL, Meert KL, Zinter MS, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Mareboina M, Notterman DA, Sapru A. Healthcare Burden and Resource Utilization After Pediatric Acute Respiratory Distress Syndrome: A Secondary Analysis of the Collaborative Pediatric Critical Care Research Network Acute Respiratory Distress Syndrome Study. Pediatr Crit Care Med. 2024 Mar 06. PMID: 38445974.
      View in: PubMed
    3. Logan GE, Banks RK, Reeder R, Miller K, Mourani PM, Bennett TD, Bourque SL, Meert KL, Zimmerman J, Maddux AB. Association of an In-Hospital Desirability of Outcomes Ranking Scale With Postdischarge Health-Related Quality of Life: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation. Pediatr Crit Care Med. 2024 Feb 14. PMID: 38353586.
      View in: PubMed
    4. Maddux AB, Miller KR, Sierra YL, Bennett TD, Watson RS, Spear M, Pyle LL, Mourani PM. Recovery Trajectories in Children Requiring 3 or More Days of Invasive Ventilation. Crit Care Med. 2024 Jan 09. PMID: 38193769.
      View in: PubMed
    5. Sharma M, Brown AW, Powell NM, Rajaram N, Tong L, Mourani PM, Schootman M. Racial and skin color mediated disparities in pulse oximetry in infants and young children. Paediatr Respir Rev. 2024 Jan 05. PMID: 38233229.
      View in: PubMed
    6. Chu VT, Tsitsiklis A, Mick E, Ambroggio L, Kalantar KL, Glascock A, Osborne CM, Wagner BD, Matthay MA, DeRisi JL, Calfee CS, Mourani PM, Langelier CR. The antibiotic resistance reservoir of the lung microbiome expands with age in a population of critically ill patients. Nat Commun. 2024 Jan 02; 15(1):92. PMID: 38168095.
      View in: PubMed
    7. Janas AM, Miller KR, Stence NV, Wyrwa JM, Ruzas CM, Messer R, Mourani PM, Fink EL, Maddux AB. Utility of Early Magnetic Resonance Imaging to Enhance Outcome Prediction in Critically Ill Children with Severe Traumatic Brain Injury. Neurocrit Care. 2023 Dec 26. PMID: 38148435.
      View in: PubMed
    8. Yates AR, Naim MY, Reeder RW, Ahmed T, Banks RK, Bell MJ, Berg RA, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Notterman D, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Viteri S, Wessel D, Wolfe HA, Yeh J, Zuppa AF, Sutton RM, Meert KL. Early Cardiac Arrest Hemodynamics, End-Tidal Co2, and Outcome in Pediatric Extracorporeal Cardiopulmonary Resuscitation: Secondary Analysis of the ICU-RESUScitation Project Dataset (2016-2021). Pediatr Crit Care Med. 2023 Dec 13. PMID: 38088765.
      View in: PubMed
    9. Zinna SS, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Cooper KK, Michael Dean J, Wesley Diddle J, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Harding ML, Hehir DA, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Berg RA, Sutton RM. Chest compressions for pediatric organized rhythms: A hemodynamic and outcomes analysis. Resuscitation. 2024 Jan; 194:110068. PMID: 38052273.
      View in: PubMed
    10. Morgan RW, Reeder RW, Bender D, Cooper KK, Friess SH, Graham K, Meert KL, Mourani PM, Murray R, Nadkarni VM, Nataraj C, Palmer CA, Srivastava N, Tilford B, Wolfe HA, Yates AR, Berg RA, Sutton RM. Associations Between End-Tidal Carbon Dioxide During Pediatric Cardiopulmonary Resuscitation, Cardiopulmonary Resuscitation Quality, and Survival. Circulation. 2024 Jan 30; 149(5):367-378. PMID: 37929615.
      View in: PubMed
    11. Gardner MM, Hehir DA, Reeder RW, Ahmed T, Bell MJ, Berg RA, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Harding ML, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Topjian AA. Identification of post-cardiac arrest blood pressure thresholds associated with outcomes in children: an ICU-Resuscitation study. Crit Care. 2023 10 07; 27(1):388. PMID: 37805481.
      View in: PubMed
    12. Osborne CM, Langelier C, Kamm J, Williamson K, Ambroggio L, Reeder RW, Locandro C, Kirk Harris J, Wagner BD, Maddux AB, Caldera S, Lyden A, Soesanto V, Sim?es EAF, Leroue MK, Carpenter TC, Hall MW, Zuppa AF, Carcillo JA, Meert KL, Pollack MM, McQuillen PS, Notterman DA, DeRisi J, Mourani PM. Viral Detection by Reverse Transcriptase Polymerase Chain Reaction in Upper Respiratory Tract and Metagenomic RNA Sequencing in Lower Respiratory Tract in Critically Ill Children With Suspected Lower Respiratory Tract Infection. Pediatr Crit Care Med. 2024 Jan 01; 25(1):e1-e11. PMID: 37732845.
      View in: PubMed
    13. Chu VT, Tsitsiklis A, Mick E, Ambroggio L, Kalantar KL, Glascock A, Osborne CM, Wagner BD, Matthay MA, DeRisi JL, Calfee CS, Mourani PM, Langelier CR. The antibiotic resistance reservoir of the lung microbiome expands with age. Res Sq. 2023 Sep 18. PMID: 37790384.
      View in: PubMed
    14. Federman M, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Kirkpatrick T, Maa T, Maitoza LA, Manga A, McQuillen PS, Meert KL, Morgan RW, Mourani PM, Nadkarni VM, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Naim MY. Survival With Favorable Neurologic Outcome and Quality of Cardiopulmonary Resuscitation Following In-Hospital Cardiac Arrest in Children With Cardiac Disease Compared With Noncardiac Disease. Pediatr Crit Care Med. 2024 Jan 01; 25(1):4-14. PMID: 37678381.
      View in: PubMed
    15. Sallee CJ, Hippensteel JA, Miller KR, Oshima K, Pham AT, Richter RP, Belperio J, Sierra YL, Schwingshackl A, Mourani PM, Schmidt EP, Sapru A, Maddux AB. Endothelial Glycocalyx Degradation Patterns in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome: A Single Center Retrospective Observational Study. J Intensive Care Med. 2024 Mar; 39(3):277-287. PMID: 37670670.
      View in: PubMed
    16. Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Association of CPR simulation program characteristics with simulated and actual performance during paediatric in-hospital cardiac arrest. Resuscitation. 2023 10; 191:109939. PMID: 37625580.
      View in: PubMed
    17. VanBuren JM, Hall M, Zuppa AF, Mourani PM, Carcillo J, Dean JM, Watt K, Holubkov R. The Design of Nested Adaptive Clinical Trials of Multiple Organ Dysfunction Syndrome Children in a Single Study. Pediatr Crit Care Med. 2023 Dec 01; 24(12):e635-e646. PMID: 37498156.
      View in: PubMed
    18. Novak T, Crawford JC, Hahn G, Hall MW, Thair SA, Newhams MM, Chou J, Mourani PM, Tarquinio KM, Markovitz B, Loftis LL, Weiss SL, Higgerson R, Schwarz AJ, Pinto NP, Thomas NJ, Gedeit RG, Sanders RC, Mahapatra S, Coates BM, Cvijanovich NZ, Ackerman KG, Tellez DW, McQuillen P, Kurachek SC, Shein SL, Lange C, Thomas PG, Randolph AG. Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza. Front Immunol. 2023; 14:1220028. PMID: 37533854.
      View in: PubMed
    19. Morgan RW, Reeder RW, Ahmed T, Bell MJ, Berger JT, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Himebauch AS, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Page K, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Berg RA, Sutton RM. Outcomes and characteristics of cardiac arrest in children with pulmonary hypertension: A secondary analysis of the ICU-RESUS clinical trial. Resuscitation. 2023 09; 190:109897. PMID: 37406760.
      View in: PubMed
    20. Stenson EK, Banks RK, Reeder RW, Maddux AB, Zimmerman J, Meert KL, Mourani PM. Fluid Balance and Its Association With Mortality and Health-Related Quality of Life: A Nonprespecified Secondary Analysis of the Life After Pediatric Sepsis Evaluation. Pediatr Crit Care Med. 2023 Oct 01; 24(10):829-839. PMID: 37260317.
      View in: PubMed
    21. Mick E, Tsitsiklis A, Kamm J, Kalantar KL, Caldera S, Lyden A, Tan M, Detweiler AM, Neff N, Osborne CM, Williamson KM, Soesanto V, Leroue M, Maddux AB, Sim?es EA, Carpenter TC, Wagner BD, DeRisi JL, Ambroggio L, Mourani PM, Langelier CR. Integrated host/microbe metagenomics enables accurate lower respiratory tract infection diagnosis in critically ill children. J Clin Invest. 2023 04 03; 133(7). PMID: 37009900.
      View in: PubMed
    22. Leroue MK, Williamson KM, Curtin PC, Sontag MK, Wagner BD, Ambroggio L, Bixby M, Busgang SA, Murphy SE, Peterson LA, Vevang KR, Sipe CJ, Kirk Harris J, Reeder RW, Locandro C, Carpenter TC, Maddux AB, Sim?es EAF, Osborne CM, Robertson CE, Langelier C, Carcillo JA, Meert KL, Pollack MM, McQuillen PS, Mourani PM. Tobacco smoke exposure, the lower airways microbiome and outcomes of ventilated children. Pediatr Res. 2023 08; 94(2):660-667. PMID: 36750739.
      View in: PubMed
    23. Cashen K, Sutton RM, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Michael Dean J, Wesley Diddle J, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, KirkpatrickN T, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Page K, Pollack MM, Qunibi D, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Meert KL. Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes. Resuscitation. 2023 04; 185:109673. PMID: 36565948.
      View in: PubMed
    24. Stanski NL, Gist KM, Pickett K, Brinton JT, Sadlowski J, Wong HR, Mourani P, Soranno DE, Kendrick J, Stenson EK. Electrolyte derangements in critically ill children receiving balanced versus unbalanced crystalloid fluid resuscitation. BMC Nephrol. 2022 Dec 06; 23(1):388. PMID: 36474179.
      View in: PubMed
    25. Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG. DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036. PMID: 35986912.
      View in: PubMed
    26. Berg RA, Morgan RW, Reeder RW, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023 01 01; 51(1):91-102. PMID: 36519983.
      View in: PubMed
    27. Spear MB, Miller K, Press C, Ruzas C, LaVelle J, Mourani PM, Bennett TD, Maddux AB. Unplanned Admissions, Emergency Department Visits, and Epilepsy After Critical Neurological Illness Requiring Prolonged Mechanical Ventilation in Children. Neurohospitalist. 2023 Jan; 13(1):31-39. PMID: 36531841.
      View in: PubMed
    28. Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host Respiratory Transcriptome Signature Associated with Poor Outcome in Children with Influenza-Staphylococcus aureus Pneumonia. J Infect Dis. 2022 09 28; 226(7):1286-1294. PMID: 35899844.
      View in: PubMed
    29. Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 11 01; 23(11):908-918. PMID: 36053072.
      View in: PubMed
    30. Ohlstrom DJ, Sul C, Vohwinkel CU, Hernandez-Lagunas L, Karimpour-Fard A, Mourani PM, Carpenter TC, Nozik ES, Sucharov CC. Plasma microRNA and metabolic changes associated with pediatric acute respiratory distress syndrome: a prospective cohort study. Sci Rep. 2022 08 26; 12(1):14560. PMID: 36028738.
      View in: PubMed
    31. Salud D, Reeder RW, Banks RK, Meert KL, Berg RA, Zuppa A, Newth CJ, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Varni JW, Zimmerman JJ. Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock. Pediatr Crit Care Med. 2022 08 01; 23(8):635-645. PMID: 35687094.
      View in: PubMed
    32. Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 10 01; 23(10):784-792. PMID: 35880872.
      View in: PubMed
    33. Mick E, Tsitsiklis A, Spottiswoode N, Caldera S, Serpa PH, Detweiler AM, Neff N, Pisco AO, Li LM, Retallack H, Ratnasiri K, Williamson KM, Soesanto V, Sim?es EAF, Smith C, Abuogi L, Kistler A, Wagner BD, DeRisi JL, Ambroggio L, Mourani PM, Langelier CR. Upper airway gene expression shows a more robust adaptive immune response to SARS-CoV-2 in children. Nat Commun. 2022 07 08; 13(1):3937. PMID: 35803954.
      View in: PubMed
    34. Kamps NN, Banks R, Reeder RW, Berg RA, Newth CJ, Pollack MM, Meert KL, Carcillo JA, Mourani PM, Sorenson S, Varni JW, Cengiz P, Zimmerman JJ. The Association of Early Corticosteroid Therapy With Clinical and Health-Related Quality of Life Outcomes in Children With Septic Shock. Pediatr Crit Care Med. 2022 09 01; 23(9):687-697. PMID: 35695852.
      View in: PubMed
    35. Maddux AB, VanBuren JM, Jensen AR, Holubkov R, Alvey JS, McQuillen P, Mourani PM, Meert KL, Burd RS. Post-discharge rehabilitation and functional recovery after pediatric injury. Injury. 2022 Aug; 53(8):2795-2803. PMID: 35680434.
      View in: PubMed
    36. Vo M, Miller K, Bennett TD, Mourani PM, LaVelle J, Carpenter TC, Scott Watson R, Pyle LL, Maddux AB. Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness. Pediatr Pulmonol. 2022 07; 57(7):1651-1659. PMID: 35438830.
      View in: PubMed
    37. Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A. Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 07 01; 23(7):e319-e328. PMID: 35452018.
      View in: PubMed
    38. Levy RA, Reiter PD, Spear M, Santana A, Silveira L, Cox S, Mourani PM, Maddux AB. Peripheral Vasoactive Administration in Critically Ill Children With Shock: A Single-Center Retrospective Cohort Study. Pediatr Crit Care Med. 2022 08 01; 23(8):618-625. PMID: 35446810.
      View in: PubMed
    39. Bolin EH, Spray BJ, Mourani PM, Porter C, Collins RT. Mortality among infants of diabetic mothers with hypertrophic cardiomyopathy. J Matern Fetal Neonatal Med. 2022 Dec; 35(25):9893-9899. PMID: 35440277.
      View in: PubMed
    40. Tsitsiklis A, Osborne CM, Kamm J, Williamson K, Kalantar K, Dudas G, Caldera S, Lyden A, Tan M, Neff N, Soesanto V, Harris JK, Ambroggio L, Maddux AB, Carpenter TC, Reeder RW, Locandro C, Sim?es EAF, Leroue MK, Hall MW, Zuppa AF, Carcillo J, Meert KL, Sapru A, Pollack MM, McQuillen PS, Notterman DA, Dean JM, Zinter MS, Wagner BD, DeRisi JL, Mourani PM, Langelier CR. Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics. Lancet Microbe. 2022 04; 3(4):e284-e293. PMID: 35544065.
      View in: PubMed
    41. Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 03 08; 327(10):934-945. PMID: 35258533.
      View in: PubMed
    42. Maddux AB, Zimmerman JJ, Banks RK, Reeder RW, Meert KL, Czaja AS, Berg RA, Sapru A, Carcillo JA, Newth CJL, Quasney MW, Mourani PM. Health Resource Use in Survivors of Pediatric Septic Shock in the United States. Pediatr Crit Care Med. 2022 06 01; 23(6):e277-e288. PMID: 35250001.
      View in: PubMed
    43. Maddux AB, Mourani PM, Miller K, Carpenter TC, LaVelle J, Pyle LL, Watson RS, Bennett TD. Identifying Long-Term Morbidities and Health Trajectories After Prolonged Mechanical Ventilation in Children Using State All Payer Claims Data. Pediatr Crit Care Med. 2022 04 01; 23(4):e189-e198. PMID: 35250002.
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    45. Bhalla AK, Klein MJ, Modesto I Alapont V, Emeriaud G, Kneyber MCJ, Medina A, Cruces P, Diaz F, Takeuchi M, Maddux AB, Mourani PM, Camilo C, White BR, Yehya N, Pappachan J, Di Nardo M, Shein S, Newth C, Khemani R. Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study. Crit Care. 2022 01 03; 26(1):2. PMID: 34980228.
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    63. Coleman RD, Chartan CA, Mourani PM. Intensive care management of right ventricular failure and pulmonary hypertension crises. Pediatr Pulmonol. 2021 03; 56(3):636-648. PMID: 33561307.
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    80. Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG. RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. J Allergy Clin Immunol. 2020 06; 145(6):1673-1680.e11. PMID: 32035159.
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    87. Hornik CP, Yogev R, Mourani PM, Watt KM, Sullivan JE, Atz AM, Speicher D, Al-Uzri A, Adu-Darko M, Payne EH, Gelber CE, Lin S, Harper B, Melloni C, Cohen-Wolkowiez M, Gonzalez D. Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents. J Clin Pharmacol. 2019 12; 59(12):1606-1619. PMID: 31317556.
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    99. Abman SH, Mourani P, Wagner B. Reply to Ong and Schechter: Is It Acceptable to Assess Prenatal Smoking Risk to Infants without Considering Socioeconomic Status? Am J Respir Crit Care Med. 2018 04 01; 197(7):966-967. PMID: 29111777.
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    103. Maddux AB, DeWitt PE, Mourani PM, Bennett TD. Hospital Readmissions After Pediatric Trauma. Pediatr Crit Care Med. 2018 01; 19(1):e31-e40. PMID: 29210926.
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    104. Ladd AK, Skillman HE, Haemer MA, Mourani PM. Preventing Underfeeding and Overfeeding: A Clinician's Guide to the Acquisition and Implementation of Indirect Calorimetry. Nutr Clin Pract. 2018 Apr; 33(2):198-205. PMID: 28549221.
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    105. Langelier C, White CV, Sontag MK, Mourani PM, DeRisi JL. Complete Genome Sequence of a Divergent Human Rhinovirus C Isolate from an Infant with Severe Community-Acquired Pneumonia in Colorado, USA. Genome Announc. 2017 Nov 30; 5(48). PMID: 29192071.
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    106. Wagner BD, Sontag MK, Harris JK, Miller JI, Morrow L, Robertson CE, Stephens MJ, Poindexter BB, Abman SH, Mourani PM. Prenatal complications are associated with the postnatal airway host response and microbiota in intubated preterm infants. J Matern Fetal Neonatal Med. 2019 May; 32(9):1499-1506. PMID: 29157044.
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    107. Leroue MK, Harris JK, Burgess KM, Stevens MJ, Miller JI, Sontag MK, Sierra YL, Wagner BD, Mourani PM. Molecular analysis of endotracheal tube biofilms and tracheal aspirates in the pediatric intensive care unit. Adv Pediatr Res. 2017 Dec; 4(3). PMID: 29963643.
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    108. Gunville CF, Miller JI, Carpenter TC, Mourani PM. Vitamin D Levels in Premature Children Admitted to the Hospital with Viral Respiratory Infection. Pediatr Allergy Immunol Pulmonol. 2017 Sep; 30(3):148-154. PMID: 35923008.
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    109. Mourani PM, Sontag MK. Ventilator-Associated Pneumonia in Critically Ill Children: A New Paradigm. Pediatr Clin North Am. 2017 10; 64(5):1039-1056. PMID: 28941534.
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    110. Morrow LA, Wagner BD, Ingram DA, Poindexter BB, Schibler K, Cotten CM, Dagle J, Sontag MK, Mourani PM, Abman SH. Antenatal Determinants of Bronchopulmonary Dysplasia and Late Respiratory Disease in Preterm Infants. Am J Respir Crit Care Med. 2017 08 01; 196(3):364-374. PMID: 28249118.
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    111. Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG. Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection. J Infect Dis. 2017 07 01; 216(1):14-21. PMID: 28531322.
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    112. Carlton EF, Sontag MK, Younoszai A, DiMaria MV, Miller JI, Poindexter BB, Abman SH, Mourani PM. Reliability of Echocardiographic Indicators of Pulmonary Vascular Disease in Preterm Infants at Risk for Bronchopulmonary Dysplasia. J Pediatr. 2017 07; 186:29-33. PMID: 28411949.
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    113. Wagner BD, Sontag MK, Harris JK, Miller JI, Morrow L, Robertson CE, Stephens M, Poindexter BB, Abman SH, Mourani PM. Airway Microbial Community Turnover Differs by BPD Severity in Ventilated Preterm Infants. PLoS One. 2017; 12(1):e0170120. PMID: 28129336.
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    114. Goss KN, Everett AD, Mourani PM, Baker CD, Abman SH. Addressing the challenges of phenotyping pediatric pulmonary vascular disease. Pulm Circ. 2017 Mar; 7(1):7-19. PMID: 28680562.
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    115. Lynch AM, Wagner BD, Mandava N, Palestine AG, Mourani PM, McCourt EA, Oliver SC, Abman SH. The Relationship of Novel Plasma Proteins in the Early Neonatal Period With Retinopathy of Prematurity. Invest Ophthalmol Vis Sci. 2016 Sep 01; 57(11):5076-5082. PMID: 27679852.
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    116. Goldenberg NA, Daniels SR, Mourani PM, Hamblin F, Stowe A, Powell S, Ford DE, Ellen J. Enhanced Infrastructure for Optimizing the Design and Execution of Clinical Trials and Longitudinal Cohort Studies in the Era of Precision Medicine. J Pediatr. 2016 Apr; 171:300-6.e1-2. PMID: 26787376.
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    117. Mourani PM, Abman SH. Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia. Clin Perinatol. 2015 Dec; 42(4):839-55. PMID: 26593082.
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    118. Abman SH, Mourani P, Wagner B. Genomic Insights into Respiratory Outcomes after Preterm Birth. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):530-2. PMID: 26325151.
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    119. Di Maria MV, Younoszai AK, Sontag MK, Miller JI, Poindexter BB, Ingram DA, Abman SH, Mourani PM. Maturational Changes in Diastolic Longitudinal Myocardial Velocity in Preterm Infants. J Am Soc Echocardiogr. 2015 Sep; 28(9):1045-52. PMID: 26025727.
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    120. Mourani PM, Sontag MK, Younoszai A, Miller JI, Kinsella JP, Baker CD, Poindexter BB, Ingram DA, Abman SH. Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2015 Jan 01; 191(1):87-95. PMID: 25389562.
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    121. Davis SM, Maddux AB, Alonso GT, Okada CR, Mourani PM, Maahs DM. Profound hypokalemia associated with severe diabetic ketoacidosis. Pediatr Diabetes. 2016 Feb; 17(1):61-5. PMID: 25430801.
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    122. Abman SH, Baker C, Gien J, Mourani P, Galambos C. The Robyn Barst Memorial Lecture: Differences between the fetal, newborn, and adult pulmonary circulations: relevance for age-specific therapies (2013 Grover Conference series). Pulm Circ. 2014 Sep; 4(3):424-40. PMID: 25621156.
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    123. Ferdinands JM, Olsho LE, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. J Infect Dis. 2014 Sep 01; 210(5):674-83. PMID: 24676207.
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    124. Ambalavanan N, Mourani P. Pulmonary hypertension in bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol. 2014 Mar; 100(3):240-6. PMID: 24616323.
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    125. Baker CD, Abman SH, Mourani PM. Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia. Pediatr Allergy Immunol Pulmonol. 2014 Mar 01; 27(1):8-16. PMID: 24669351.
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    126. Mourani PM, Kinsella JP, Clermont G, Kong L, Perkins AM, Weissfeld L, Cutter G, Linde-Zwirble WT, Abman SH, Angus DC, Watson RS. Intensive care unit readmission during childhood after preterm birth with respiratory failure. J Pediatr. 2014 Apr; 164(4):749-755.e3. PMID: 24388320.
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    127. Eggleston HA, Gunville CF, Miller JI, Sontag MK, Mourani PM. A comparison of characteristics and outcomes in severe human metapneumovirus and respiratory syncytial virus infections in children treated in an intensive care unit. Pediatr Infect Dis J. 2013 Dec; 32(12):1330-4. PMID: 23811741.
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    128. Gunville CF, Mourani PM, Ginde AA. The role of vitamin D in prevention and treatment of infection. Inflamm Allergy Drug Targets. 2013 Aug; 12(4):239-45. PMID: 23782205.
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    129. Mourani PM, Abman SH. Pulmonary vascular disease in bronchopulmonary dysplasia: pulmonary hypertension and beyond. Curr Opin Pediatr. 2013 Jun; 25(3):329-37. PMID: 23615175.
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    130. Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke. J Pediatr. 2013 May; 162(5):1041-6.e1. PMID: 23260102.
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    131. Hancock HS, Wang M, Gist KM, Gibson E, Miyamoto SD, Mourani PM, Manco-Johnson MJ, Goldenberg NA. Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study. Cardiol Young. 2013 Jun; 23(3):344-52. PMID: 23088931.
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    132. Manco-Johnson MJ, Wang M, Goldenberg NA, Soep J, Gibson E, Knoll CM, Mourani PM. Treatment, survival, and thromboembolic outcomes of thrombotic storm in children. J Pediatr. 2012 Oct; 161(4):682-8.e1. PMID: 22578585.
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    133. Baker CD, Balasubramaniam V, Mourani PM, Sontag MK, Black CP, Ryan SL, Abman SH. Cord blood angiogenic progenitor cells are decreased in bronchopulmonary dysplasia. Eur Respir J. 2012 Dec; 40(6):1516-22. PMID: 22496315.
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    134. Branchford BR, Mourani P, Bajaj L, Manco-Johnson M, Wang M, Goldenberg NA. Risk factors for in-hospital venous thromboembolism in children: a case-control study employing diagnostic validation. Haematologica. 2012 Apr; 97(4):509-15. PMID: 22133768.
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    135. Mourani PM, Harris JK, Sontag MK, Robertson CE, Abman SH. Molecular identification of bacteria in tracheal aspirate fluid from mechanically ventilated preterm infants. PLoS One. 2011; 6(10):e25959. PMID: 22016793.
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    136. Cooper L, Moore C, Branchford B, Greffe B, Capocelli K, Kuder A, Mehta I, Mourani PM. Successful pulmonary artery embolectomy in a patient with a saddle Wilms tumor embolus. Pediatr Blood Cancer. 2012 May; 58(5):806-9. PMID: 21681933.
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    137. Gunville CF, Sontag MK, Stratton KA, Ranade DJ, Abman SH, Mourani PM. Scope and impact of early and late preterm infants admitted to the PICU with respiratory illness. J Pediatr. 2010 Aug; 157(2):209-214.e1. PMID: 20338574.
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    138. Mourani PM, Sontag MK, Ivy DD, Abman SH. Effects of long-term sildenafil treatment for pulmonary hypertension in infants with chronic lung disease. J Pediatr. 2009 Mar; 154(3):379-84, 384.e1-2. PMID: 18950791.
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    139. Abman SH, Mourani PM, Sontag M. Bronchopulmonary dysplasia: a genetic disease. Pediatrics. 2008 Sep; 122(3):658-9. PMID: 18762536.
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    140. Mourani PM, Ivy DD, Rosenberg AA, Fagan TE, Abman SH. Left ventricular diastolic dysfunction in bronchopulmonary dysplasia. J Pediatr. 2008 Feb; 152(2):291-3. PMID: 18206706.
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    141. Mourani PM, Sontag MK, Younoszai A, Ivy DD, Abman SH. Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease. Pediatrics. 2008 Feb; 121(2):317-25. PMID: 18245423.
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    142. Mourani PM, Ivy DD, Gao D, Abman SH. Pulmonary vascular effects of inhaled nitric oxide and oxygen tension in bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2004 Nov 01; 170(9):1006-13. PMID: 15184202.
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    143. Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC. Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. Circulation. 2004 Mar 16; 109(10):1299-306. PMID: 14993145.
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    144. Weiser-Evans MC, Schwartz PE, Grieshaber NA, Quinn BE, Grieshaber SS, Belknap JK, Mourani PM, Majack RA, Stenmark KR. Novel embryonic genes are preferentially expressed by autonomously replicating rat embryonic and neointimal smooth muscle cells. Circ Res. 2000 Sep 29; 87(7):608-15. PMID: 11009567.
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