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Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon.

Sawyer JR, Tian E, Thomas E, Koller M, Stangeby C, Sammartino G, Goosen L, Swanson C, Binz RL, Barlogie B, Shaughnessy J. Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon. Br J Haematol. 2009 Nov; 147(4):484-94.

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