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@uark.edu
University of Arkansas for Medical Sciences
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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature. 2010 Jun 24; 465(7301):1084-8.
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PubMed
subject areas
Animals
Biocatalysis
Cell Line
Enzyme Activation
Humans
I-kappa B Kinase
I-kappa B Proteins
Lysine
Lysophospholipids
Mice
Models, Molecular
NF-kappa B
Phosphorylation
Phosphotransferases (Alcohol Group Acceptor)
Protein Binding
Protein Structure, Tertiary
Receptor-Interacting Protein Serine-Threonine Kinases
Sphingosine
Substrate Specificity
TNF Receptor-Associated Factor 2
Tumor Necrosis Factor-alpha
Ubiquitination
Ubiquitin-Conjugating Enzymes
Ubiquitin-Protein Ligases
authors with profiles
Graham Strub