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Prostacyclin regulates bone growth via the Epac/Rap1 pathway.
Hutchison MR, White PC. Prostacyclin regulates bone growth via the Epac/Rap1 pathway. Endocrinology. 2015 Feb; 156(2):499-510.
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PubMed
subject areas
Animals
Anti-Inflammatory Agents, Non-Steroidal
Bone Development
Cattle
Cells, Cultured
Chondrocytes
Cyclooxygenase 2
Epoprostenol
Female
Growth Plate
Guanine Nucleotide Exchange Factors
Humans
Iloprost
Insulin-Like Growth Factor I
Male
Mice
Mice, Inbred C57BL
Prostaglandins I
Pyrazoles
rap1 GTP-Binding Proteins
Signal Transduction
Sulfonamides