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Nathan Avaritt

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
DivisionBiochem & Molecular Histone Epigenet
Address Biomedical Research I
1120 Marshall Street
Mail Slot # 803
Little Rock AR 72202
Phone501-526-6000
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    Collapse Research 
    Collapse research activities and funding
    W81XWH2110460     (CANNON, MARTIN)Jul 1, 2021 - Jun 30, 2024
    US Department of Defense
    Proteogenomic analysis of responders versus nonresponders in a Phase I clinical trial of Th17-inducing dendritic cell vaccination for advanced stage ovarian cancer
    Role: Principal Investigator
    R33CA173264     (TACKETT, ALAN)Sep 1, 2013 - Aug 31, 2017
    NIH
    Development of MassSQUIRM to Quantitatively Measure Lysine Methylation
    Role: Co-Investigator
    R01DA025755     (TACKETT, ALAN JACKSON)Sep 20, 2008 - Jul 31, 2013
    NIH
    Development of technology for high resolution epigenetic profiling of chromatin
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Urbaniak A, Bathula C, Chauhan J, Rai P, Thammathong J, Clark C, Heflin B, De Loose A, Avaritt N, Rodriguez A, Tackett AJ, Sen S, Banerjee S. Synthesis and Anti-Melanoma Activity of Acryloyl Pyridinone Analogues. Chem Biodivers. 2023 Dec; 20(12):e202301550. PMID: 37994208.
      View in: PubMed
    2. Avaritt NL, Byrum SD. Cutting-Edge Technologies Driving Quantitative Mass Spectrometry. J Vis Exp. 2023 03 03; (193). PMID: 37602860.
      View in: PubMed
    3. Roy Choudhury S, Heflin B, Taylor E, Koss B, Avaritt NL, Tackett AJ. CRISPR/dCas9-KRAB-Mediated Suppression of S100b Restores p53-Mediated Apoptosis in Melanoma Cells. Cells. 2023 02 24; 12(5). PMID: 36899866.
      View in: PubMed
    4. Lowenthal R, Taylor M, Gidden JA, Heflin B, Lay JO, Avaritt N, Tackett AJ, Urbaniak A. The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro. Biomed Pharmacother. 2023 May; 161:114424. PMID: 36827712.
      View in: PubMed
    5. Adams SH, Wright R, Piccolo BD, Moody B, Sikes J, Avaritt N, Chintapalli SV, Ou X. C-section increases cecal abundance of the archetypal bile acid and glucocorticoid modifying Lachnoclostridium [clostridium] scindens in mice. Physiol Rep. 2022 07; 10(13):e15363. PMID: 35778808.
      View in: PubMed
    6. Paidi SK, Rodriguez Troncoso J, Raj P, Monterroso Diaz P, Ivers JD, Lee DE, Avaritt NL, Gies AJ, Quick CM, Byrum SD, Tackett AJ, Rajaram N, Barman I. Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy. Cancer Res. 2021 11 15; 81(22):5745-5755. PMID: 34645610.
      View in: PubMed
    7. Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Moreira ARS, Bird J, Thomas CL, Avaritt N, Kharas MG, Lengner CJ, Byrum SD, MacNicol MC, Childs GV, MacNicol AM. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 2021 03 01; 162(3). PMID: 33373440.
      View in: PubMed
    8. Firwana B, Avaritt N, Shields B, Ravilla R, Makhoul I, Hutchins L, Tackett AJ, Mahmoud F. Do checkpoint inhibitors rely on gut microbiota to fight cancer? J Oncol Pharm Pract. 2018 Sep; 24(6):468-472. PMID: 28625074.
      View in: PubMed
    9. Mahmoud F, Shields B, Makhoul I, Avaritt N, Wong HK, Hutchins LF, Shalin S, Tackett AJ. Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack. Cancer Biol Ther. 2017 Jul 03; 18(7):451-469. PMID: 28513269.
      View in: PubMed
    10. Sengupta D, Byrum SD, Avaritt NL, Davis L, Shields B, Mahmoud F, Reynolds M, Orr LM, Mackintosh SG, Shalin SC, Tackett AJ. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016 Mar; 15(3):765-75. PMID: 26621846.
      View in: PubMed
    11. Udensi UK, Tackett AJ, Byrum S, Avaritt NL, Sengupta D, Moreland LW, Tchounwou PB, Isokpehi RD. Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide. J Proteomics Bioinform. 2014 Jul; 7(7):166-178. PMID: 25419056.
      View in: PubMed
    12. Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ. Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma. J Proteomics Bioinform. 2013 Mar 01; 6(3):43-50. PMID: 23976835.
      View in: PubMed
    13. Avaritt NL, Owens R, Larson SK, Reynolds M, Byrum S, Hiatt KM, Smoller BR, Tackett AJ, Cheung WL. Misregulation of Rad50 expression in melanoma cells. J Cutan Pathol. 2012 Jul; 39(7):680-684. PMID: 22725639.
      View in: PubMed
    14. Blair LP, Avaritt NL, Tackett AJ. Application of MassSQUIRM for quantitative measurements of lysine demethylase activity. J Vis Exp. 2012 Mar 11; (61). PMID: 22433969.
      View in: PubMed
    15. Byrum S, Avaritt NL, Mackintosh SG, Munkberg JM, Badgwell BD, Cheung WL, Tackett AJ. A quantitative proteomic analysis of FFPE melanoma. J Cutan Pathol. 2011 Nov; 38(11):933-6. PMID: 21883366.
      View in: PubMed
    16. Blair LP, Avaritt NL, Huang R, Cole PA, Taverna SD, Tackett AJ. MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity. Epigenetics. 2011 Apr; 6(4):490-9. PMID: 21273814.
      View in: PubMed
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