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BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1).
Williamson EA, Dadmanesh F, Koeffler HP. BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1). Oncogene. 2002 May 09; 21(20):3199-206.
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PubMed
subject areas
Adenocarcinoma
Animals
BRCA1 Protein
Breast Neoplasms
Carcinoma, Ductal, Breast
Cell Cycle
Cell Cycle Proteins
Colonic Neoplasms
COS Cells
Cyclin-Dependent Kinase Inhibitor p27
Female
Gene Expression Regulation, Neoplastic
Genes, BRCA1
Genes, Reporter
Humans
Mice
Neoplasm Proteins
Promoter Regions, Genetic
Protein Structure, Tertiary
Sequence Deletion
Transcriptional Activation
Transfection
Tumor Cells, Cultured
Tumor Suppressor Proteins