 Trichloroethylene
"Trichloroethylene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.
| Descriptor ID |
D014241
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| MeSH Number(s) |
D02.455.526.439.939
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| Concept/Terms |
Trichloroethylene- Trichloroethylene
- Trichloroethene
- Ethinyl Trichloride
- Trichloride, Ethinyl
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Below are MeSH descriptors whose meaning is more general than "Trichloroethylene".
Below are MeSH descriptors whose meaning is more specific than "Trichloroethylene".
This graph shows the total number of publications written about "Trichloroethylene" by people in UAMS Profiles by year, and whether "Trichloroethylene" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2016 | 3 | 0 | 3 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2010 | 2 | 0 | 2 | | 2009 | 3 | 0 | 3 | | 2008 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2000 | 3 | 0 | 3 | | 1999 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trichloroethylene" by people in Profiles over the past ten years.
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Choudhury SR, Byrum SD, Blossom SJ. Trichloroethylene metabolite modulates DNA methylation-dependent gene expression in Th1-polarized CD4+ T cells from autoimmune-prone mice. Toxicol Sci. 2024 May 28; 199(2):289-300.
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Blossom SJ, Cabanlong CV, Vyas KK. Developmental trichloroethylene exposure enhances predictive markers of autoimmunity in a sex-specific manner in disease-resistant female mice. Toxicol Appl Pharmacol. 2022 11 01; 454:116233.
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Blossom SJ, Melnyk SB, Simmen FA. Complex epigenetic patterns in cerebellum generated after developmental exposure to trichloroethylene and/or high fat diet in autoimmune-prone mice. Environ Sci Process Impacts. 2020 Mar 01; 22(3):583-594.
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Byrum SD, Washam CL, Patterson JD, Vyas KK, Gilbert KM, Blossom SJ. Continuous Developmental and Early Life Trichloroethylene Exposure Promoted DNA Methylation Alterations in Polycomb Protein Binding Sites in Effector/Memory CD4+ T Cells. Front Immunol. 2019; 10:2016.
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Khare S, Gokulan K, Williams K, Bai S, Gilbert KM, Blossom SJ. Irreversible effects of trichloroethylene on the gut microbial community and gut-associated immune responses in autoimmune-prone mice. J Appl Toxicol. 2019 02; 39(2):209-220.
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Blossom SJ, Fernandes L, Bai S, Khare S, Gokulan K, Yuan Y, Dewall M, Simmen FA, Gilbert KM. Opposing Actions of Developmental Trichloroethylene and High-Fat Diet Coexposure on Markers of Lipogenesis and Inflammation in Autoimmune-Prone Mice. Toxicol Sci. 2018 07 01; 164(1):313-327.
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Meadows JR, Parker C, Gilbert KM, Blossom SJ, DeWitt JC. A single dose of trichloroethylene given during development does not substantially alter markers of neuroinflammation in brains of adult mice. J Immunotoxicol. 2017 12; 14(1):95-102.
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Gilbert KM, Bai S, Barnette D, Blossom SJ. Exposure Cessation During Adulthood Did Not Prevent Immunotoxicity Caused by Developmental Exposure to Low-Level Trichloroethylene in Drinking Water. Toxicol Sci. 2017 06 01; 157(2):429-437.
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Gilbert KM, Blossom SJ, Erickson SW, Broadfoot B, West K, Bai S, Li J, Cooney CA. Chronic exposure to trichloroethylene increases DNA methylation of the Ifng promoter in CD4+ T cells. Toxicol Lett. 2016 Oct 17; 260:1-7.
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Gilbert KM, Blossom SJ, Erickson SW, Reisfeld B, Zurlinden TJ, Broadfoot B, West K, Bai S, Cooney CA. Chronic exposure to water pollutant trichloroethylene increased epigenetic drift in CD4(+) T cells. Epigenomics. 2016 05; 8(5):633-49.
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Blossom SJ, Melnyk SB, Li M, Wessinger WD, Cooney CA. Inflammatory and oxidative stress-related effects associated with neurotoxicity are maintained after exclusively prenatal trichloroethylene exposure. Neurotoxicology. 2017 03; 59:164-174.
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Yoo HS, Cichocki JA, Kim S, Venkatratnam A, Iwata Y, Kosyk O, Bodnar W, Sweet S, Knap A, Wade T, Campbell J, Clewell HJ, Melnyk SB, Chiu WA, Rusyn I. The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene. Toxicol Sci. 2015 Oct; 147(2):339-49.
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