Immunoreceptor Tyrosine-Based Inhibition Motif
"Immunoreceptor Tyrosine-Based Inhibition Motif" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.
Descriptor ID |
D061626
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MeSH Number(s) |
G02.111.570.060.040.875 G02.111.570.790.709.600.040.480
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Concept/Terms |
Immunoreceptor Tyrosine-Based Inhibition Motif- Immunoreceptor Tyrosine-Based Inhibition Motif
- Immunoreceptor Tyrosine Based Inhibition Motif
- Immuno-Receptor Tyrosine-Based Inhibition Motif
- Immuno Receptor Tyrosine Based Inhibition Motif
- Immune Receptor Tyrosine-Based Inhibition Motif
- Immune Receptor Tyrosine Based Inhibition Motif
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Below are MeSH descriptors whose meaning is more general than "Immunoreceptor Tyrosine-Based Inhibition Motif".
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Below are the most recent publications written about "Immunoreceptor Tyrosine-Based Inhibition Motif" by people in Profiles over the past ten years.