 Claudin-1
"Claudin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.
| Descriptor ID |
D062445
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| MeSH Number(s) |
D12.776.543.984.200.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Claudin-1".
Below are MeSH descriptors whose meaning is more specific than "Claudin-1".
This graph shows the total number of publications written about "Claudin-1" by people in UAMS Profiles by year, and whether "Claudin-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Claudin-1" by people in Profiles over the past ten years.
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Liu M, Yang J, Zhang Y, Zhou Z, Cui X, Zhang L, Fung KM, Zheng W, Allard FD, Yee EU, Ding K, Wu H, Liang Z, Zheng L, Fernandez-Zapico ME, Li YP, Bronze MS, Morris KT, Postier RG, Houchen CW, Yang J, Li M. ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism. Clin Cancer Res. 2018 07 01; 24(13):3186-3196.
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Meyer K, Kwon YC, Liu S, Hagedorn CH, Ray RB, Ray R. Interferon-a inducible protein 6 impairs EGFR activation by CD81 and inhibits hepatitis C virus infection. Sci Rep. 2015 Mar 11; 5:9012.
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