 Alu Elements
"Alu Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
| Descriptor ID |
D020087
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| MeSH Number(s) |
G02.111.570.080.708.330.800.800.050 G05.360.080.708.330.800.800.050 G05.360.340.024.425.800.800.050
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| Concept/Terms |
Alu Elements- Alu Elements
- Alu Element
- Element, Alu
- Elements, Alu
- Alu Family
- Alu Families
- Families, Alu
- Family, Alu
- Alu Repetitive Sequences
- Alu Repetitive Sequence
- Repetitive Sequence, Alu
- Repetitive Sequences, Alu
- Sequence, Alu Repetitive
- Sequences, Alu Repetitive
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Below are MeSH descriptors whose meaning is more general than "Alu Elements".
Below are MeSH descriptors whose meaning is more specific than "Alu Elements".
This graph shows the total number of publications written about "Alu Elements" by people in UAMS Profiles by year, and whether "Alu Elements" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alu Elements" by people in Profiles over the past ten years.
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Henriksen RA, Jenjaroenpun P, Sj?str?m IB, Jensen KR, Prada-Luengo I, Wongsurawat T, Nookaew I, Regenberg B. Circular DNA in the human germline and its association with recombination. Mol Cell. 2022 01 06; 82(1):209-217.e7.
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Szafranski P, Kosmider E, Liu Q, Karolak JA, Currie L, Parkash S, Kahler SG, Roeder E, Littlejohn RO, DeNapoli TS, Shardonofsky FR, Henderson C, Powers G, Poisson V, B?rub? D, Oligny L, Michaud JL, Janssens S, De Coen K, Van Dorpe J, Dheedene A, Harting MT, Weaver MD, Khan AM, Tatevian N, Wambach J, Gibbs KA, Popek E, Gambin A, Stankiewicz P. LINE- and Alu-containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV. Hum Mutat. 2018 12; 39(12):1916-1925.
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Knight Johnson A, Schaefer GB, Lee J, Hu Y, Del Gaudio D. Alu-mediated deletion of PIGL in a Patient with CHIME syndrome. Am J Med Genet A. 2017 May; 173(5):1378-1382.
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