Protein Kinase C-alpha
"Protein Kinase C-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.
| Descriptor ID |
D051571
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.725.100
|
| Concept/Terms |
Protein Kinase C-alpha- Protein Kinase C-alpha
- Protein Kinase C(alpha)
- PKC-alpha Serine-Threonine Kinase
- PKC alpha Serine Threonine Kinase
- Serine-Threonine Kinase, PKC-alpha
- Protein Kinase C alpha
|
Below are MeSH descriptors whose meaning is more general than "Protein Kinase C-alpha".
Below are MeSH descriptors whose meaning is more specific than "Protein Kinase C-alpha".
This graph shows the total number of publications written about "Protein Kinase C-alpha" by people in UAMS Profiles by year, and whether "Protein Kinase C-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Kinase C-alpha" by people in Profiles over the past ten years.
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Nowak G, Megyesi J. Protein kinase Ca mediates recovery of renal and mitochondrial functions following acute injury. FEBS J. 2020 05; 287(9):1830-1849.
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Nowak G, Bakajsova D. Protein kinase C-a interaction with F0F1-ATPase promotes F0F1-ATPase activity and reduces energy deficits in injured renal cells. J Biol Chem. 2015 Mar 13; 290(11):7054-66.