Transducin
"Transducin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodopsin to cyclic GMP phosphodiesterase and is pivotal in the visual excitation process. Activation of rhodopsin on the outer membrane of rod and cone cells causes GTP to bind to transducin followed by dissociation of the alpha subunit-GTP complex from the beta/gamma subunits of transducin. The alpha subunit-GTP complex activates the cyclic GMP phosphodiesterase which catalyzes the hydrolysis of cyclic GMP to 5'-GMP. This leads to closure of the sodium and calcium channels and therefore hyperpolarization of the rod cells. EC 3.6.1.-.
Descriptor ID |
D015293
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MeSH Number(s) |
D08.811.277.040.330.300.200.800 D12.644.360.375.940 D12.776.157.325.332.940 D12.776.476.375.940 D12.776.543.325.800
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Concept/Terms |
Transducin- Transducin
- Transducin G-Protein (Gt)
- Gt, Transducin G-Protein
- G-Protein Gt, Transducin
- Gt, Transducin G Protein
- Transducin G-Protein Gt
- G-Protein, Inhibitory Gt
- G Protein, Inhibitory Gt
- Gt G-Protein, Inhibitory
- Inhibitory Gt G-Protein
gamma-Transducin- gamma-Transducin
- gamma Transducin
- Transducin, gamma Subunit
- gamma Subunit Transducin
alpha-Transducin- alpha-Transducin
- alpha Transducin
- Transducin, alpha Subunit
- alpha Subunit Transducin
beta-Transducin- beta-Transducin
- beta Transducin
- Transducin, beta Subunit
- beta Subunit Transducin
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Below are MeSH descriptors whose meaning is more general than "Transducin".
Below are MeSH descriptors whose meaning is more specific than "Transducin".
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Below are the most recent publications written about "Transducin" by people in Profiles over the past ten years.