Monocrotaline
"Monocrotaline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
| Descriptor ID |
D016686
|
| MeSH Number(s) |
D03.132.716.500 D03.438.772.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Monocrotaline".
Below are MeSH descriptors whose meaning is more specific than "Monocrotaline".
This graph shows the total number of publications written about "Monocrotaline" by people in UAMS Profiles by year, and whether "Monocrotaline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monocrotaline" by people in Profiles over the past ten years.
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Farahmand F, Malik A, Sharma A, Bagchi AK, Singal PK. Role of oxidative stress versus lipids in monocrotaline-induced pulmonary hypertension and right heart failure. Physiol Rep. 2021 11; 9(22):e15090.
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Gubrij IB, Pangle AK, Pang L, Johnson LG. Reversal of MicroRNA Dysregulation in an Animal Model of Pulmonary Hypertension. PLoS One. 2016; 11(1):e0147827.