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Lymphocyte Function-Associated Antigen-1

"Lymphocyte Function-Associated Antigen-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.


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This graph shows the total number of publications written about "Lymphocyte Function-Associated Antigen-1" by people in UAMS Profiles by year, and whether "Lymphocyte Function-Associated Antigen-1" was a major or minor topic of these publications.
Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 1993 and 1998 and 2001 and 2003 and 2004
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