Methapyrilene
"Methapyrilene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.
Descriptor ID |
D008701
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MeSH Number(s) |
D02.092.782.258.368.500 D03.383.725.050.440
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Concept/Terms |
Methapyrilene- Methapyrilene
- N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine
- Thenylpyramine
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Below are MeSH descriptors whose meaning is more general than "Methapyrilene".
Below are MeSH descriptors whose meaning is more specific than "Methapyrilene".
This graph shows the total number of publications written about "Methapyrilene" by people in UAMS Profiles by year, and whether "Methapyrilene" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2018 | 1 | 0 | 1 | 2017 | 2 | 0 | 2 | 1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methapyrilene" by people in Profiles over the past ten years.
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Tryndyak V, Kindrat I, Dreval K, Churchwell MI, Beland FA, Pogribny IP. Effect of aflatoxin B1, benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells. Food Chem Toxicol. 2018 Nov; 121:214-223.
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Kindrat I, Dreval K, Shpyleva S, Tryndyak V, de Conti A, Mudalige TK, Chen T, Erstenyuk AM, Beland FA, Pogribny IP. Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro. Toxicol Lett. 2017 Nov 05; 281:65-73.
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Shpyleva S, Dreval K, de Conti A, Kindrat I, Melnyk S, Yan J, Chen T, Beland FA, Pogribny IP. Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats. Toxicol Sci. 2017 03 01; 156(1):190-198.
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