Substantia Nigra
"Substantia Nigra" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.
| Descriptor ID |
D013378
|
| MeSH Number(s) |
A08.186.211.132.659.822.731 A08.186.211.653.822.731
|
| Concept/Terms |
Substantia Nigra- Substantia Nigra
- Nigra, Substantia
- Nigras, Substantia
- Substantia Nigras
|
Below are MeSH descriptors whose meaning is more general than "Substantia Nigra".
Below are MeSH descriptors whose meaning is more specific than "Substantia Nigra".
This graph shows the total number of publications written about "Substantia Nigra" by people in UAMS Profiles by year, and whether "Substantia Nigra" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 1993 | 1 | 0 | 1 |
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Below are the most recent publications written about "Substantia Nigra" by people in Profiles over the past ten years.
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Lee JY, Castelli V, Sanberg PR, Borlongan CV. Probing Gut Participation in Parkinson's Disease Pathology and Treatment via Stem Cell Therapy. Int J Mol Sci. 2023 Jun 25; 24(13).
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Salvatore MF, Terrebonne J, Fields V, Nodurft D, Runfalo C, Latimer B, Ingram DK. Initiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine. Neurobiol Aging. 2016 Jan; 37:192-207.
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Zawada WM, Mrak RE, Biedermann J, Palmer QD, Gentleman SM, Aboud O, Griffin WS. Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation. Acta Neuropathol Commun. 2015 Feb 03; 3:9.