 Mendelian Randomization Analysis
"Mendelian Randomization Analysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The use of the GENETIC VARIATION of known functions or phenotypes to correlate the causal effects of those functions or phenotypes with a disease outcome.
| Descriptor ID |
D057182
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| MeSH Number(s) |
E05.318.416.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mendelian Randomization Analysis".
Below are MeSH descriptors whose meaning is more specific than "Mendelian Randomization Analysis".
This graph shows the total number of publications written about "Mendelian Randomization Analysis" by people in UAMS Profiles by year, and whether "Mendelian Randomization Analysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Mendelian Randomization Analysis" by people in Profiles over the past ten years.
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Went M, Duran-Lozano L, Halldorsson GH, Gunnell A, Ugidos-Damboriena N, Law P, Ekdahl L, Sud A, Thorleifsson G, Thodberg M, Olafsdottir T, Lamarca-Arrizabalaga A, Cafaro C, Niroula A, Ajore R, Lopez de Lapuente Portilla A, Ali Z, Pertesi M, Goldschmidt H, Stefansdottir L, Kristinsson SY, Stacey SN, Love TJ, Rognvaldsson S, Hajek R, Vodicka P, Pettersson-Kymmer U, Sp?th F, Schinke C, Van Rhee F, Sulem P, Ferkingstad E, Hjorleifsson Eldjarn G, Mellqvist UH, Jonsdottir I, Morgan G, Sonneveld P, Waage A, Weinhold N, Thomsen H, F?rsti A, Hansson M, Juul-Vangsted A, Thorsteinsdottir U, Hemminki K, Kaiser M, Rafnar T, Stefansson K, Houlston R, Nilsson B. Deciphering the genetics and mechanisms of predisposition to multiple myeloma. Nat Commun. 2024 Aug 05; 15(1):6644.
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Tin Tin S, Smith-Byrne K, Ferrari P, Rinaldi S, McCullough ML, Teras LR, Manjer J, Giles G, Le Marchand L, Haiman CA, Wilkens LR, Chen Y, Hankinson S, Tworoger S, Eliassen AH, Willett WC, Ziegler RG, Fuhrman BJ, Sieri S, Agnoli C, Cauley J, Menon U, Fourkala EO, Rohan TE, Kaaks R, Reeves GK, Key TJ. Alcohol intake and endogenous sex hormones in women: Meta-analysis of cohort studies and Mendelian randomization. Cancer. 2024 Oct 01; 130(19):3375-3386.
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Richmond RC, Howe LJ, Heilbron K, Jones S, Liu J, Wang X, Weedon MN, Rutter MK, Lawlor DA, Davey Smith G, Vetter C. Correlations in sleeping patterns and circadian preference between spouses. Commun Biol. 2023 11 13; 6(1):1156.
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Howe LJ, Rasheed H, Jones PR, Boomsma DI, Evans DM, Giannelis A, Hayward C, Hopper JL, Hughes A, Lahtinen H, Li S, Lind PA, Martin NG, Martikainen P, Medland SE, Morris TT, Nivard MG, Pingault JB, Silventoinen K, Smith JA, Willoughby EA, Wilson JF, ?svold BO, N?ss ?E, Davey Smith G, Kaprio J, Brumpton B, Davies NM. Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study. Int J Epidemiol. 2023 10 05; 52(5):1579-1591.
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Borges MC, Haycock P, Zheng J, Hemani G, Howe LJ, Schmidt AF, Staley JR, Lumbers RT, Henry A, Lemaitre RN, Gaunt TR, Holmes MV, Davey Smith G, Hingorani AD, Lawlor DA. The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study. Hum Mol Genet. 2022 11 28; 31(23):4034-4054.
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Howe LJ, Tudball M, Davey Smith G, Davies NM. Interpreting Mendelian-randomization estimates of the effects of categorical exposures such as disease status and educational attainment. Int J Epidemiol. 2022 06 13; 51(3):948-957.
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Howe LJ, Nivard MG, Morris TT, Hansen AF, Rasheed H, Cho Y, Chittoor G, Ahlskog R, Lind PA, Palviainen T, van der Zee MD, Cheesman R, Mangino M, Wang Y, Li S, Klaric L, Ratliff SM, Bielak LF, Nygaard M, Giannelis A, Willoughby EA, Reynolds CA, Balbona JV, Andreassen OA, Ask H, Baras A, Bauer CR, Boomsma DI, Campbell A, Campbell H, Chen Z, Christofidou P, Corfield E, Dahm CC, Dokuru DR, Evans LM, de Geus EJC, Giddaluru S, Gordon SD, Harden KP, Hill WD, Hughes A, Kerr SM, Kim Y, Kweon H, Latvala A, Lawlor DA, Li L, Lin K, Magnus P, Magnusson PKE, Mallard TT, Martikainen P, Mills MC, Nj?lstad PR, Overton JD, Pedersen NL, Porteous DJ, Reid J, Silventoinen K, Southey MC, Stoltenberg C, Tucker-Drob EM, Wright MJ, Hewitt JK, Keller MC, Stallings MC, Lee JJ, Christensen K, Kardia SLR, Peyser PA, Smith JA, Wilson JF, Hopper JL, H?gg S, Spector TD, Pingault JB, Plomin R, Havdahl A, Bartels M, Martin NG, Oskarsson S, Justice AE, Millwood IY, Hveem K, Naess ?, Willer CJ, ?svold BO, Koellinger PD, Kaprio J, Medland SE, Walters RG, Benjamin DJ, Turley P, Evans DM, Davey Smith G, Hayward C, Brumpton B, Hemani G, Davies NM. Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects. Nat Genet. 2022 05; 54(5):581-592.
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Howe LJ, Brumpton B, Rasheed H, ?svold BO, Davey Smith G, Davies NM. Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study. Elife. 2022 03 18; 11.
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Arathimos R, Ronaldson A, Howe LJ, Fabbri C, Hagenaars S, Hotopf M, Gaughran F, Lewis CM, Dregan A. Vitamin D and the risk of treatment-resistant and atypical depression: A Mendelian randomization study. Transl Psychiatry. 2021 11 04; 11(1):561.
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Rosoff DB, Smith GD, Lohoff FW. Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis. JAMA Psychiatry. 2021 02 01; 78(2):151-160.
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Dardani C, Howe LJ, Mukhopadhyay N, Stergiakouli E, Wren Y, Humphries K, Davies A, Ho K, Weinberg SM, Marazita ML, Mangold E, Ludwig KU, Relton CL, Davey Smith G, Lewis SJ, Sandy J, Davies NM, Sharp GC. Cleft lip/palate and educational attainment: cause, consequence or correlation? A Mendelian randomization study. Int J Epidemiol. 2020 08 01; 49(4):1282-1293.
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Howe LJ, Hemani G, Lesseur C, Gaborieau V, Ludwig KU, Mangold E, Brennan P, Ness AR, St Pourcain B, Davey Smith G, Lewis SJ. Evaluating shared genetic influences on nonsyndromic cleft lip/palate and oropharyngeal neoplasms. Genet Epidemiol. 2020 11; 44(8):924-933.
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Brumpton B, Sanderson E, Heilbron K, Hartwig FP, Harrison S, Vie G?, Cho Y, Howe LD, Hughes A, Boomsma DI, Havdahl A, Hopper J, Neale M, Nivard MG, Pedersen NL, Reynolds CA, Tucker-Drob EM, Grotzinger A, Howe L, Morris T, Li S, Auton A, Windmeijer F, Chen WM, Bj?rngaard JH, Hveem K, Willer C, Evans DM, Kaprio J, Davey Smith G, ?svold BO, Hemani G, Davies NM. Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses. Nat Commun. 2020 07 14; 11(1):3519.
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Went M, Cornish AJ, Law PJ, Kinnersley B, van Duin M, Weinhold N, F?rsti A, Hansson M, Sonneveld P, Goldschmidt H, Morgan GJ, Hemminki K, Nilsson B, Kaiser M, Houlston RS. Search for multiple myeloma risk factors using Mendelian randomization. Blood Adv. 2020 05 26; 4(10):2172-2179.
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Davies NM, Howe LJ, Brumpton B, Havdahl A, Evans DM, Davey Smith G. Within family Mendelian randomization studies. Hum Mol Genet. 2019 11 21; 28(R2):R170-R179.
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Howe LJ, Richardson TG, Arathimos R, Alvizi L, Passos-Bueno MR, Stanier P, Nohr E, Ludwig KU, Mangold E, Knapp M, Stergiakouli E, Pourcain BS, Smith GD, Sandy J, Relton CL, Lewis SJ, Hemani G, Sharp GC. Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate. Epigenomics. 2019 02; 11(2):133-145.
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Went M, Sud A, Law PJ, Johnson DC, Weinhold N, F?rsti A, van Duin M, Mitchell JS, Chen B, Kuiper R, Stephens OW, Bertsch U, Campo C, Einsele H, Gregory WM, Henrion M, Hillengass J, Hoffmann P, Jackson GH, Lenive O, Nickel J, N?then MM, da Silva Filho MI, Thomsen H, Walker BA, Broyl A, Davies FE, Langer C, Hansson M, Kaiser M, Sonneveld P, Goldschmidt H, Hemminki K, Nilsson B, Morgan GJ, Houlston RS. Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach. Blood Cancer J. 2017 06 16; 7(6):e573.
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