 Hypoxia-Ischemia, Brain
"Hypoxia-Ischemia, Brain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Descriptor ID |
D020925
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| MeSH Number(s) |
C10.228.140.300.150.716 C10.228.140.624.500 C14.907.253.092.716
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| Concept/Terms |
Hypoxia-Ischemia, Brain- Hypoxia-Ischemia, Brain
- Brain Hypoxia-Ischemias
- Hypoxia Ischemia, Brain
- Hypoxia-Ischemias, Brain
- Brain Ischemia-Hypoxia
- Brain Ischemia Hypoxia
- Brain Ischemia-Hypoxias
- Ischemia-Hypoxias, Brain
- Ischemia-Hypoxia, Brain
- Ischemia Hypoxia, Brain
- Brain Hypoxia-Ischemia
- Brain Hypoxia Ischemia
Hypoxic-Ischemic Encephalopathy- Hypoxic-Ischemic Encephalopathy
- Encephalopathies, Hypoxic-Ischemic
- Hypoxic Ischemic Encephalopathy
- Hypoxic-Ischemic Encephalopathies
- Ischemic-Hypoxic Encephalopathy
- Encephalopathies, Ischemic-Hypoxic
- Encephalopathy, Ischemic-Hypoxic
- Ischemic Hypoxic Encephalopathy
- Ischemic-Hypoxic Encephalopathies
- Encephalopathy, Hypoxic-Ischemic
- Encephalopathy, Hypoxic Ischemic
Anoxic-Ischemic Encephalopathy- Anoxic-Ischemic Encephalopathy
- Anoxic Ischemic Encephalopathy
- Anoxic-Ischemic Encephalopathies
- Encephalopathies, Anoxic-Ischemic
- Encephalopathy, Anoxic-Ischemic
- Encephalopathy, Anoxic Ischemic
Cerebral Hypoxia-Ischemia- Cerebral Hypoxia-Ischemia
- Cerebral Hypoxia Ischemia
- Cerebral Hypoxia-Ischemias
- Hypoxia-Ischemias, Cerebral
- Hypoxia-Ischemia, Cerebral
- Hypoxia Ischemia, Cerebral
- Ischemia-Hypoxia, Cerebral
- Ischemia Hypoxia, Cerebral
- Cerebral Ischemia-Hypoxia
- Cerebral Ischemia Hypoxia
- Cerebral Ischemia-Hypoxias
- Ischemia-Hypoxias, Cerebral
Anoxia-Ischemia, Brain- Anoxia-Ischemia, Brain
- Anoxia Ischemia, Brain
- Anoxia-Ischemias, Brain
- Brain Anoxia-Ischemias
- Brain Ischemia-Anoxia
- Brain Ischemia Anoxia
- Brain Ischemia-Anoxias
- Ischemia-Anoxias, Brain
- Ischemia-Anoxia, Brain
- Ischemia Anoxia, Brain
- Brain Anoxia-Ischemia
- Brain Anoxia Ischemia
Anoxia-Ischemia, Cerebral- Anoxia-Ischemia, Cerebral
- Anoxia Ischemia, Cerebral
- Anoxia-Ischemias, Cerebral
- Cerebral Anoxia-Ischemias
- Cerebral Ischemia-Anoxia
- Cerebral Ischemia Anoxia
- Cerebral Ischemia-Anoxias
- Ischemia-Anoxias, Cerebral
- Ischemia-Anoxia, Cerebral
- Ischemia Anoxia, Cerebral
- Cerebral Anoxia-Ischemia
- Cerebral Anoxia Ischemia
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Below are MeSH descriptors whose meaning is more general than "Hypoxia-Ischemia, Brain".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Ischemia, Brain".
This graph shows the total number of publications written about "Hypoxia-Ischemia, Brain" by people in UAMS Profiles by year, and whether "Hypoxia-Ischemia, Brain" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 2 | 0 | 2 | | 2023 | 2 | 0 | 2 | | 2021 | 2 | 0 | 2 | | 2019 | 3 | 0 | 3 | | 2018 | 3 | 0 | 3 | | 2017 | 4 | 0 | 4 | | 2016 | 5 | 0 | 5 | | 2015 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2007 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hypoxia-Ischemia, Brain" by people in Profiles over the past ten years.
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Simpson S, Steinmeyer S, Nguyen T, Nienaber T. Positive outcome in a patient with severe hypoxic-ischaemic encephalopathy. BMJ Case Rep. 2024 Jun 05; 17(6).
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Turner MJ, Rumpel JA, Spray BJ, Stence N, Neuberger I, Frymoyer A, Chock VY, Courtney S, Gist K. Urine biomarkers of acute kidney injury and association with brain MRI abnormalities in neonatal hypoxic-ischemic encephalopathy. J Perinatol. 2024 Aug; 44(8):1203-1207.
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Presacco A, Chirumamilla VC, Vezina G, Li R, Du Plessis A, Massaro AN, Govindan RB. Prediction of outcome of hypoxic-ischemic encephalopathy in newborns undergoing therapeutic hypothermia using heart rate variability. J Perinatol. 2024 Apr; 44(4):521-527.
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Molloy EJ, Branagan A, Hurley T, Quirke F, Devane D, Taneri PE, El-Dib M, Bloomfield FH, Maeso B, Pilon B, Bonifacio SL, Wusthoff CJ, Chalak L, Bearer C, Murray DM, Badawi N, Campbell S, Mulkey S, Gressens P, Ferriero DM, de Vries LS, Walker K, Kay S, Boylan G, Gale C, Robertson NJ, D'Alton M, Gunn A, Nelson KB. Neonatal encephalopathy and hypoxic-ischemic encephalopathy: moving from controversy to consensus definitions and subclassification. Pediatr Res. 2023 Dec; 94(6):1860-1863.
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Rumpel JA, Spray BJ, Frymoyer A, Rogers S, Cho SH, Ranabothu S, Blaszak R, Courtney SE, Chock VY. Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia. Pediatr Nephrol. 2023 08; 38(8):2839-2849.
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Li R, Lee JK, Govindan RB, Graham EM, Everett AD, Perin J, Vezina G, Tekes A, Chen MW, Northington F, Parkinson C, O'Kane A, McGowan M, Krein C, Al-Shargabi T, Chang T, Massaro AN. Plasma Biomarkers of Evolving Encephalopathy and Brain Injury in Neonates with Hypoxic-Ischemic Encephalopathy. J Pediatr. 2023 01; 252:146-153.e2.
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Chen MW, Lee JK, Vezina G, Tekes A, Perin J, Li R, O'Kane A, McGowan M, Chang T, Parkinson C, Krein C, Al-Shargabi T, Northington FJ, Brady KM, Massaro AN, Govindan RB. The Utility of Cerebral Autoregulation Indices in Detecting Severe Brain Injury Varies by Cooling Treatment Phase in Neonates with Hypoxic-Ischemic Encephalopathy. Dev Neurosci. 2022; 44(4-5):363-372.
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Rumpel J, Spray BJ, Chock VY, Kirkley MJ, Slagle CL, Frymoyer A, Cho SH, Gist KM, Blaszak R, Poindexter B, Courtney SE. Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia. J Pediatr. 2022 02; 241:133-140.e3.
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Mulkey SB, Polglase GR. Cerebral oxygen saturation-a useful bedside vital sign for neonatal encephalopathy. J Perinatol. 2021 11; 41(11):2577-2579.
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Massaro AN, Lee JK, Vezina G, Glass P, O'Kane A, Li R, Chang T, Brady K, Govindan R. Exploratory Assessment of the Relationship Between Hemoglobin Volume Phase Index, Magnetic Resonance Imaging, and Functional Outcome in Neonates with Hypoxic-Ischemic Encephalopathy. Neurocrit Care. 2021 08; 35(1):121-129.
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Kota S, Massaro AN, Chang T, Al-Shargabi T, Cristante C, Vezina G, du Plessis A, Govindan RB. Prognostic Value of Continuous Electroencephalogram Delta Power in Neonates With Hypoxic-Ischemic Encephalopathy. J Child Neurol. 2020 07; 35(8):517-525.
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Govindan RB, Massaro A, Vezina G, Chang T, du Plessis A. Identifying an optimal epoch length for spectral analysis of heart rate of critically-ill infants. Comput Biol Med. 2019 10; 113:103391.
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Govindan RB, Massaro AN, Kota S, Grabowski RC, Wilson JD, Plessis AD. Effect of EKG Sampling Rate on Heart Rate Variability Analysis. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:6780-6783.
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Wu YW, Goodman AM, Chang T, Mulkey SB, Gonzalez FF, Mayock DE, Juul SE, Mathur AM, Van Meurs K, McKinstry RC, Redline RW. Placental pathology and neonatal brain MRI in a randomized trial of erythropoietin for hypoxic-ischemic encephalopathy. Pediatr Res. 2020 04; 87(5):879-884.
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Lucke AM, Shetty AN, Hagan JL, Walton A, Stafford TD, Chu ZD, Rhee CJ, Kaiser JR, Sanz Cortes M. Early proton magnetic resonance spectroscopy during and after therapeutic hypothermia in perinatal hypoxic-ischemic encephalopathy. Pediatr Radiol. 2019 06; 49(7):941-950.
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Dizon MLV, Rao R, Hamrick SE, Zaniletti I, DiGeronimo R, Natarajan G, Kaiser JR, Flibotte J, Lee KS, Smith D, Yanowitz T, Mathur AM, Massaro AN. Practice variation in anti-epileptic drug use for neonatal hypoxic-ischemic encephalopathy among regional NICUs. BMC Pediatr. 2019 02 27; 19(1):67.
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Shetty AN, Lucke AM, Liu P, Sanz Cortes M, Hagan JL, Chu ZD, Hunter JV, Lu H, Lee W, Kaiser JR. Cerebral oxygen metabolism during and after therapeutic hypothermia in neonatal hypoxic-ischemic encephalopathy: a feasibility study using magnetic resonance imaging. Pediatr Radiol. 2019 02; 49(2):224-233.
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Basu SK, Ottolini K, Govindan V, Mashat S, Vezina G, Wang Y, Ridore M, Chang T, Kaiser JR, Massaro AN. Early Glycemic Profile Is Associated with Brain Injury Patterns on Magnetic Resonance Imaging in Hypoxic Ischemic Encephalopathy. J Pediatr. 2018 12; 203:137-143.
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Campbell H, Govindan RB, Kota S, Al-Shargabi T, Metzler M, Andescavage N, Chang T, Vezina G, du Plessis A, Massaro AN. Autonomic Dysfunction in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia Impairs Physiological Responses to Routine Care Events. J Pediatr. 2018 05; 196:38-44.
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Massaro AN, Wu YW, Bammler TK, Comstock B, Mathur A, McKinstry RC, Chang T, Mayock DE, Mulkey SB, Van Meurs K, Juul S. Plasma Biomarkers of Brain Injury in Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr. 2018 03; 194:67-75.e1.
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Cuevas Guaman M, Lucke AM, Hagan JL, Kaiser JR. Bleeding Complications and Mortality in Neonates Receiving Therapeutic Hypothermia and Extracorporeal Membrane Oxygenation. Am J Perinatol. 2018 Feb; 35(3):271-276.
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Luton A, Hernandez J, Patterson CR, Nielsen-Farrell J, Thompson A, Kaiser JR. Preventing Pressure Injuries in Neonates Undergoing Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy: An Interprofessional Quality Improvement Project. Adv Neonatal Care. 2017 Aug; 17(4):237-244.
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Metzler M, Govindan R, Al-Shargabi T, Vezina G, Andescavage N, Wang Y, du Plessis A, Massaro AN. Pattern of brain injury and depressed heart rate variability in newborns with hypoxic ischemic encephalopathy. Pediatr Res. 2017 Sep; 82(3):438-443.
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Mulkey SB, Ramakrishnaiah RH, McKinstry RC, Chang T, Mathur AM, Mayock DE, Van Meurs KP, Schaefer GB, Luo C, Bai S, Juul SE, Wu YW. Erythropoietin and Brain Magnetic Resonance Imaging Findings in Hypoxic-Ischemic Encephalopathy: Volume of Acute Brain Injury and 1-Year Neurodevelopmental Outcome. J Pediatr. 2017 07; 186:196-199.
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Limaye K, Jadhav AP. Delayed Transient Cortical Blindness from Hypoxic Ischemic Encephalopathy. Am J Med. 2017 Sep; 130(9):e391-e392.
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Massaro AN, Campbell HE, Metzler M, Al-Shargabi T, Wang Y, du Plessis A, Govindan RB. Effect of Temperature on Heart Rate Variability in Neonatal ICU Patients With Hypoxic-Ischemic Encephalopathy. Pediatr Crit Care Med. 2017 Apr; 18(4):349-354.
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Al-Shargabi T, Govindan RB, Dave R, Metzler M, Wang Y, du Plessis A, Massaro AN. Inflammatory cytokine response and reduced heart rate variability in newborns with hypoxic-ischemic encephalopathy. J Perinatol. 2017 06; 37(6):668-672.
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Schneebaum Sender N, Govindan RB, Whitehead MT, Massaro AN, Metzler M, Wang J, Cheng YI, du Plessis AJ. Cerebral modulation of the autonomic nervous system in term infants. J Perinatol. 2017 05; 37(5):558-562.
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Govindan RB, Massaro A, Vezina G, Tsuchida T, Cristante C, du Plessis A. Does relative or absolute EEG power have prognostic value in HIE setting? Clin Neurophysiol. 2017 01; 128(1):14-15.
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Basu SK, Salemi JL, Gunn AJ, Kaiser JR. Hyperglycaemia in infants with hypoxic-ischaemic encephalopathy is associated with improved outcomes after therapeutic hypothermia: a post hoc analysis of the CoolCap Study. Arch Dis Child Fetal Neonatal Ed. 2017 Jul; 102(4):F299-F306.
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Stafford TD, Hagan JL, Sitler CG, Fernandes CJ, Kaiser JR. Therapeutic Hypothermia During Neonatal Transport: Active Cooling Helps Reach the Target. Ther Hypothermia Temp Manag. 2017 Jun; 7(2):88-94.
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Wu YW, Mathur AM, Chang T, McKinstry RC, Mulkey SB, Mayock DE, Van Meurs KP, Rogers EE, Gonzalez FF, Comstock BA, Juul SE, Msall ME, Bonifacio SL, Glass HC, Massaro AN, Dong L, Tan KW, Heagerty PJ, Ballard RA. High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial. Pediatrics. 2016 06; 137(6).
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Lingappan K, Kaiser JR, Srinivasan C, Gunn AJ. Relationship between PCO2 and unfavorable outcome in infants with moderate-to-severe hypoxic ischemic encephalopathy. Pediatr Res. 2016 08; 80(2):204-8.
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Bagwell TA, Abramo TJ, Albert GW, Orsborn JW, Storm EA, Hobart-Porter NW, Thompson TM, Ocal E, Hu Z, Nick T. Cerebral oximetry with blood volume index and capnography in intubated and hyperventilated patients. Am J Emerg Med. 2016 Jun; 34(6):1102-7.
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Govindan RB, Massaro A, Chang T, Vezina G, du Plessis A. A novel technique for quantitative bedside monitoring of neurovascular coupling. J Neurosci Methods. 2016 Feb 01; 259:135-142.
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Basu SK, Kaiser JR, Guffey D, Minard CG, Guillet R, Gunn AJ. Hypoglycaemia and hyperglycaemia are associated with unfavourable outcome in infants with hypoxic ischaemic encephalopathy: a post hoc analysis of the CoolCap Study. Arch Dis Child Fetal Neonatal Ed. 2016 Mar; 101(2):F149-55.
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Massaro AN, Govindan RB, Vezina G, Chang T, Andescavage NN, Wang Y, Al-Shargabi T, Metzler M, Harris K, du Plessis AJ. Impaired cerebral autoregulation and brain injury in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. J Neurophysiol. 2015 Aug; 114(2):818-24.
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Mulkey SB, Yap VL, Bai S, Ramakrishnaiah RH, Glasier CM, Bornemeier RA, Schmitz ML, Bhutta AT. Amplitude-integrated EEG in newborns with critical congenital heart disease predicts preoperative brain magnetic resonance imaging findings. Pediatr Neurol. 2015 Jun; 52(6):599-605.
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