Hypothermia, Induced
"Hypothermia, Induced" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.
Descriptor ID |
D007036
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MeSH Number(s) |
E02.258.750
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Concept/Terms |
Moderate Hypothermia, Induced- Moderate Hypothermia, Induced
- Induced Moderate Hypothermia
- Induced Moderate Hypothermias
- Moderate Hypothermias, Induced
Mild Hypothermia, Induced- Mild Hypothermia, Induced
- Induced Mild Hypothermia
- Induced Mild Hypothermias
- Mild Hypothermias, Induced
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Below are MeSH descriptors whose meaning is more general than "Hypothermia, Induced".
Below are MeSH descriptors whose meaning is more specific than "Hypothermia, Induced".
This graph shows the total number of publications written about "Hypothermia, Induced" by people in UAMS Profiles by year, and whether "Hypothermia, Induced" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 2 | 0 | 2 | 2023 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2020 | 1 | 1 | 2 | 2019 | 2 | 2 | 4 | 2018 | 1 | 1 | 2 | 2017 | 3 | 0 | 3 | 2016 | 2 | 2 | 4 | 2015 | 2 | 0 | 2 | 2012 | 1 | 2 | 3 | 2007 | 0 | 1 | 1 | 2003 | 1 | 0 | 1 | 2002 | 1 | 1 | 2 | 2001 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 1997 | 1 | 0 | 1 | 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hypothermia, Induced" by people in Profiles over the past ten years.
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Simpson S, Steinmeyer S, Nguyen T, Nienaber T. Positive outcome in a patient with severe hypoxic-ischaemic encephalopathy. BMJ Case Rep. 2024 Jun 05; 17(6).
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Turner MJ, Rumpel JA, Spray BJ, Stence N, Neuberger I, Frymoyer A, Chock VY, Courtney S, Gist K. Urine biomarkers of acute kidney injury and association with brain MRI abnormalities in neonatal hypoxic-ischemic encephalopathy. J Perinatol. 2024 Aug; 44(8):1203-1207.
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Presacco A, Chirumamilla VC, Vezina G, Li R, Du Plessis A, Massaro AN, Govindan RB. Prediction of outcome of hypoxic-ischemic encephalopathy in newborns undergoing therapeutic hypothermia using heart rate variability. J Perinatol. 2024 Apr; 44(4):521-527.
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Rumpel JA, Spray BJ, Frymoyer A, Rogers S, Cho SH, Ranabothu S, Blaszak R, Courtney SE, Chock VY. Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia. Pediatr Nephrol. 2023 08; 38(8):2839-2849.
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Li R, Lee JK, Govindan RB, Graham EM, Everett AD, Perin J, Vezina G, Tekes A, Chen MW, Northington F, Parkinson C, O'Kane A, McGowan M, Krein C, Al-Shargabi T, Chang T, Massaro AN. Plasma Biomarkers of Evolving Encephalopathy and Brain Injury in Neonates with Hypoxic-Ischemic Encephalopathy. J Pediatr. 2023 01; 252:146-153.e2.
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Chen MW, Lee JK, Vezina G, Tekes A, Perin J, Li R, O'Kane A, McGowan M, Chang T, Parkinson C, Krein C, Al-Shargabi T, Northington FJ, Brady KM, Massaro AN, Govindan RB. The Utility of Cerebral Autoregulation Indices in Detecting Severe Brain Injury Varies by Cooling Treatment Phase in Neonates with Hypoxic-Ischemic Encephalopathy. Dev Neurosci. 2022; 44(4-5):363-372.
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Rumpel J, Spray BJ, Chock VY, Kirkley MJ, Slagle CL, Frymoyer A, Cho SH, Gist KM, Blaszak R, Poindexter B, Courtney SE. Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia. J Pediatr. 2022 02; 241:133-140.e3.
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Alnabelsi TS, Faulkner SP, Cook M, Freeman K, Shelton J, Paranzino M, Nerusu S, Smyth SS, Gupta VA. Passive antipyretic therapy is not as effective as invasive hypothermia for maintaining normothermia after cardiac arrest. Am J Emerg Med. 2021 Dec; 50:202-206.
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Massaro AN, Lee JK, Vezina G, Glass P, O'Kane A, Li R, Chang T, Brady K, Govindan R. Exploratory Assessment of the Relationship Between Hemoglobin Volume Phase Index, Magnetic Resonance Imaging, and Functional Outcome in Neonates with Hypoxic-Ischemic Encephalopathy. Neurocrit Care. 2021 08; 35(1):121-129.
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Chacon-Portillo MA, Mossad EB, Zea-Vera R, Beckerman Z, Binsalamah ZM, Adachi I, Mery CM, Imamura M, Heinle JS, Fraser CD. Sickle Cell-Related Complications in Patients Undergoing Cardiopulmonary Bypass. World J Pediatr Congenit Heart Surg. 2020 09; 11(5):565-571.
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Bashtawi Y, Almuwaqqat Z. Therapeutic Hypothermia in STEMI. Cardiovasc Revasc Med. 2021 08; 29:77-84.
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Kota S, Massaro AN, Chang T, Al-Shargabi T, Cristante C, Vezina G, du Plessis A, Govindan RB. Prognostic Value of Continuous Electroencephalogram Delta Power in Neonates With Hypoxic-Ischemic Encephalopathy. J Child Neurol. 2020 07; 35(8):517-525.
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Soar J, Maconochie I, Wyckoff MH, Olasveengen TM, Singletary EM, Greif R, Aickin R, Bhanji F, Donnino MW, Mancini ME, Wyllie JP, Zideman D, Andersen LW, Atkins DL, Aziz K, Bendall J, Berg KM, Berry DC, Bigham BL, Bingham R, Couto TB, B?ttiger BW, Borra V, Bray JE, Breckwoldt J, Brooks SC, Buick J, Callaway CW, Carlson JN, Cassan P, Castr?n M, Chang WT, Charlton NP, Cheng A, Chung SP, Considine J, Couper K, Dainty KN, Dawson JA, de Almeida MF, de Caen AR, Deakin CD, Drennan IR, Duff JP, Epstein JL, Escalante R, Gazmuri RJ, Gilfoyle E, Granfeldt A, Guerguerian AM, Guinsburg R, Hatanaka T, Holmberg MJ, Hood N, Hosono S, Hsieh MJ, Isayama T, Iwami T, Jensen JL, Kapadia V, Kim HS, Kleinman ME, Kudenchuk PJ, Lang E, Lavonas E, Liley H, Lim SH, Lockey A, Lofgren B, Ma MH, Markenson D, Meaney PA, Meyran D, Mildenhall L, Monsieurs KG, Montgomery W, Morley PT, Morrison LJ, Nadkarni VM, Nation K, Neumar RW, Ng KC, Nicholson T, Nikolaou N, Nishiyama C, Nuthall G, Ohshimo S, Okamoto D, O'Neil B, Yong-Kwang Ong G, Paiva EF, Parr M, Pellegrino JL, Perkins GD, Perlman J, Rabi Y, Reis A, Reynolds JC, Ristagno G, Roehr CC, Sakamoto T, Sandroni C, Schexnayder SM, Scholefield BR, Shimizu N, Skrifvars MB, Smyth MA, Stanton D, Swain J, Szyld E, Tijssen J, Travers A, Trevisanuto D, Vaillancourt C, Van de Voorde P, Velaphi S, Wang TL, Weiner G, Welsford M, Woodin JA, Yeung J, Nolan JP, Hazinski MF. 2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. Circulation. 2019 12 10; 140(24):e826-e880.
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Govindan RB, Massaro A, Vezina G, Chang T, du Plessis A. Identifying an optimal epoch length for spectral analysis of heart rate of critically-ill infants. Comput Biol Med. 2019 10; 113:103391.
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Wu YW, Goodman AM, Chang T, Mulkey SB, Gonzalez FF, Mayock DE, Juul SE, Mathur AM, Van Meurs K, McKinstry RC, Redline RW. Placental pathology and neonatal brain MRI in a randomized trial of erythropoietin for hypoxic-ischemic encephalopathy. Pediatr Res. 2020 04; 87(5):879-884.
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Lucke AM, Shetty AN, Hagan JL, Walton A, Stafford TD, Chu ZD, Rhee CJ, Kaiser JR, Sanz Cortes M. Early proton magnetic resonance spectroscopy during and after therapeutic hypothermia in perinatal hypoxic-ischemic encephalopathy. Pediatr Radiol. 2019 06; 49(7):941-950.
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Dizon MLV, Rao R, Hamrick SE, Zaniletti I, DiGeronimo R, Natarajan G, Kaiser JR, Flibotte J, Lee KS, Smith D, Yanowitz T, Mathur AM, Massaro AN. Practice variation in anti-epileptic drug use for neonatal hypoxic-ischemic encephalopathy among regional NICUs. BMC Pediatr. 2019 02 27; 19(1):67.
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Shetty AN, Lucke AM, Liu P, Sanz Cortes M, Hagan JL, Chu ZD, Hunter JV, Lu H, Lee W, Kaiser JR. Cerebral oxygen metabolism during and after therapeutic hypothermia in neonatal hypoxic-ischemic encephalopathy: a feasibility study using magnetic resonance imaging. Pediatr Radiol. 2019 02; 49(2):224-233.
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Basu SK, Ottolini K, Govindan V, Mashat S, Vezina G, Wang Y, Ridore M, Chang T, Kaiser JR, Massaro AN. Early Glycemic Profile Is Associated with Brain Injury Patterns on Magnetic Resonance Imaging in Hypoxic Ischemic Encephalopathy. J Pediatr. 2018 12; 203:137-143.
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Campbell H, Govindan RB, Kota S, Al-Shargabi T, Metzler M, Andescavage N, Chang T, Vezina G, du Plessis A, Massaro AN. Autonomic Dysfunction in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia Impairs Physiological Responses to Routine Care Events. J Pediatr. 2018 05; 196:38-44.
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Cuevas Guaman M, Lucke AM, Hagan JL, Kaiser JR. Bleeding Complications and Mortality in Neonates Receiving Therapeutic Hypothermia and Extracorporeal Membrane Oxygenation. Am J Perinatol. 2018 Feb; 35(3):271-276.
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Luton A, Hernandez J, Patterson CR, Nielsen-Farrell J, Thompson A, Kaiser JR. Preventing Pressure Injuries in Neonates Undergoing Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy: An Interprofessional Quality Improvement Project. Adv Neonatal Care. 2017 Aug; 17(4):237-244.
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Massaro AN, Campbell HE, Metzler M, Al-Shargabi T, Wang Y, du Plessis A, Govindan RB. Effect of Temperature on Heart Rate Variability in Neonatal ICU Patients With Hypoxic-Ischemic Encephalopathy. Pediatr Crit Care Med. 2017 Apr; 18(4):349-354.
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Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC, Clark AE, Dean JM. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. N Engl J Med. 2017 01 26; 376(4):318-329.
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Schneebaum Sender N, Govindan RB, Whitehead MT, Massaro AN, Metzler M, Wang J, Cheng YI, du Plessis AJ. Cerebral modulation of the autonomic nervous system in term infants. J Perinatol. 2017 05; 37(5):558-562.
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Govindan RB, Massaro A, Vezina G, Tsuchida T, Cristante C, du Plessis A. Does relative or absolute EEG power have prognostic value in HIE setting? Clin Neurophysiol. 2017 01; 128(1):14-15.
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Basu SK, Salemi JL, Gunn AJ, Kaiser JR. Hyperglycaemia in infants with hypoxic-ischaemic encephalopathy is associated with improved outcomes after therapeutic hypothermia: a post hoc analysis of the CoolCap Study. Arch Dis Child Fetal Neonatal Ed. 2017 Jul; 102(4):F299-F306.
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Stafford TD, Hagan JL, Sitler CG, Fernandes CJ, Kaiser JR. Therapeutic Hypothermia During Neonatal Transport: Active Cooling Helps Reach the Target. Ther Hypothermia Temp Manag. 2017 Jun; 7(2):88-94.
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Govindan RB, Kota S, Al-Shargabi T, Massaro AN, Chang T, du Plessis A. Effect of electrocardiogram interference on cortico-cortical connectivity analysis and a possible solution. J Neurosci Methods. 2016 09 01; 270:76-84.
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Lingappan K, Kaiser JR, Srinivasan C, Gunn AJ. Relationship between PCO2 and unfavorable outcome in infants with moderate-to-severe hypoxic ischemic encephalopathy. Pediatr Res. 2016 08; 80(2):204-8.
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Dunn AL, Reed T, Stewart C, Levy RA. Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. Lab Med. 2016 May; 47(2):149-54.
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Govindan RB, Massaro A, Chang T, Vezina G, du Plessis A. A novel technique for quantitative bedside monitoring of neurovascular coupling. J Neurosci Methods. 2016 Feb 01; 259:135-142.
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Basu SK, Kaiser JR, Guffey D, Minard CG, Guillet R, Gunn AJ. Hypoglycaemia and hyperglycaemia are associated with unfavourable outcome in infants with hypoxic ischaemic encephalopathy: a post hoc analysis of the CoolCap Study. Arch Dis Child Fetal Neonatal Ed. 2016 Mar; 101(2):F149-55.
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Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC, Dean JM. Therapeutic hypothermia after out-of-hospital cardiac arrest in children. N Engl J Med. 2015 May 14; 372(20):1898-908.
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