 Neural Cell Adhesion Molecule L1
"Neural Cell Adhesion Molecule L1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for proper nervous system development. Neural cell adhesion molecule L1 consists of six Ig domains, five fibronectin domains, a transmembrane region and an intracellular domain. Two splicing variants are known: a neuronal form that contains a four-amino acid RSLE sequence in the cytoplasmic domain, and a non-neuronal form that lacks the RSLE sequence. Mutations in the L1 gene result in L1 disease. Neural cell adhesion molecule L1 is predominantly expressed during development in neurons and Schwann cells; involved in cell adhesion, neuronal migration, axonal growth and pathfinding, and myelination.
| Descriptor ID |
D039842
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| MeSH Number(s) |
D12.776.395.550.200.250.520.578 D12.776.543.550.200.250.520.578 D23.050.301.350.250.520.578
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| Concept/Terms |
Neural Cell Adhesion Molecule L1- Neural Cell Adhesion Molecule L1
- NILE Glycoprotein
- Glycoprotein, NILE
- Nerve Growth Factor-Inducible Large External Glycoprotein
- Nerve Growth Factor Inducible Large External Glycoprotein
- CALL Protein
- CamL1 Gene Product
- F11 Glycoprotein
- L1CAM
- NILE Protein
- Cell Adhesion Molecule L1
- Cell Surface Glycoprotein L1
- Neural Adhesion Molecule L1
- NGF-Inducible Glycoprotein
- Glycoprotein, NGF-Inducible
- NGF Inducible Glycoprotein
- L1 Cell Adhesion Molecule
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This graph shows the total number of publications written about "Neural Cell Adhesion Molecule L1" by people in UAMS Profiles by year, and whether "Neural Cell Adhesion Molecule L1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neural Cell Adhesion Molecule L1" by people in Profiles over the past ten years.
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Luke MP, Brown RE, Clarke DB. Polysialylated - neural cell adhesion molecule (PSA-NCAM) promotes recovery of vision after the critical period. Mol Cell Neurosci. 2020 09; 107:103527.
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Fadare O, Roma AA, Desouki MM, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Zheng W, Hecht JL, Parkash V, Wang XJ. The significance of L1CAM expression in clear cell carcinoma of the endometrium. Histopathology. 2018 02; 72(3):532-538.
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