Prefrontal Cortex
"Prefrontal Cortex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the mediodorsal nucleus of the thalamus. The prefrontal cortex receives afferent fibers from numerous structures of the diencephalon, mesencephalon, and limbic system as well as cortical afferents of visual, auditory, and somatic origin.
Descriptor ID |
D017397
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MeSH Number(s) |
A08.186.211.730.885.287.500.270.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Prefrontal Cortex".
Below are MeSH descriptors whose meaning is more specific than "Prefrontal Cortex".
This graph shows the total number of publications written about "Prefrontal Cortex" by people in UAMS Profiles by year, and whether "Prefrontal Cortex" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2023 | 0 | 2 | 2 | 2022 | 0 | 1 | 1 | 2021 | 0 | 3 | 3 | 2020 | 0 | 3 | 3 | 2019 | 3 | 1 | 4 | 2018 | 6 | 0 | 6 | 2017 | 1 | 4 | 5 | 2016 | 2 | 1 | 3 | 2015 | 2 | 0 | 2 | 2014 | 0 | 3 | 3 | 2013 | 3 | 2 | 5 | 2012 | 3 | 3 | 6 | 2011 | 1 | 1 | 2 | 2010 | 2 | 0 | 2 | 2009 | 1 | 0 | 1 | 2008 | 1 | 2 | 3 | 2007 | 2 | 1 | 3 | 2005 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2002 | 1 | 1 | 2 | 2000 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prefrontal Cortex" by people in Profiles over the past ten years.
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Campos-Cardoso R, Desa ZR, Fitzgerald BL, Moore AG, Duhon JL, Landar VA, Clem RL, Cummings KA. The mouse dorsal peduncular cortex encodes fear memory. Cell Rep. 2024 Apr 23; 43(4):114097.
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Addicott MA, Kinney KR, Saldana S, Ip EH, DeMaioNewton H, Bickel WK, Hanlon CA. A randomized controlled trial of intermittent theta burst stimulation to the medial prefrontal cortex for tobacco use disorder: Clinical efficacy and safety. Drug Alcohol Depend. 2024 May 01; 258:111278.
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Addicott MA, Oliveto AH, Daughters SB. Smoking status affects cognitive, emotional and neural-connectivity response to distress-inducing auditory feedback. Drug Alcohol Depend. 2023 05 01; 246:109855.
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Han LT, Cohen MS, He LK, Green LM, Knowlton BJ, Castel AD, Rissman J. Establishing a causal role for left ventrolateral prefrontal cortex in value-directed memory encoding with high-definition transcranial direct current stimulation. Neuropsychologia. 2023 03 12; 181:108489.
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Gandy K, Scoggins MA, Phillips N, van der Plas E, Fellah S, Jacola LM, Pui CH, Hudson MM, Reddick WE, Sitaram R, Krull KR. Sex-Based Differences in Functional Brain Activity During Working Memory in Survivors of Pediatric Acute Lymphoblastic Leukemia. JNCI Cancer Spectr. 2022 03 02; 6(2).
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Carl E, Shevorykin A, Liskiewicz A, Alberico R, Belal A, Mahoney M, Bouchard E, Ray A, Sheffer CE. Increasing Physical Activity among Breast Cancer Survivors by Modulating Temporal Orientation with rTMS: Feasibility and Potential Efficacy. Int J Environ Res Public Health. 2021 09 24; 18(19).
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Adams TG, Cisler JM, Kelmendi B, George JR, Kichuk SA, Averill CL, Anticevic A, Abdallah CG, Pittenger C. Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies. Depress Anxiety. 2022 01; 39(1):37-48.
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Steele JS, Bertocci M, Eckstrand K, Chase HW, Stiffler R, Aslam H, Lockovich J, Bebko G, Phillips ML. A specific neural substrate predicting current and future impulsivity in young adults. Mol Psychiatry. 2021 09; 26(9):4919-4930.
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Carl E, Liskiewicz A, Rivard C, Alberico R, Belal A, Mahoney MC, Quisenberry AJ, Bickel WK, Sheffer CE. Dosing parameters for the effects of high-frequency transcranial magnetic stimulation on smoking cessation: study protocol for a randomized factorial sham-controlled clinical trial. BMC Psychol. 2020 May 01; 8(1):42.
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Koscik TR, Man V, Jahn A, Lee CH, Cunningham WA. Decomposing the neural pathways in a simple, value-based choice. Neuroimage. 2020 07 01; 214:116764.
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Trapp NT, Bruss J, King Johnson M, Uitermarkt BD, Garrett L, Heinzerling A, Wu C, Koscik TR, Ten Eyck P, Boes AD. Reliability of targeting methods in TMS for depression: Beam F3 vs. 5.5 cm. Brain Stimul. 2020 May - Jun; 13(3):578-581.
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Sullivan DR, Morrison FG, Wolf EJ, Logue MW, Fortier CB, Salat DH, Fonda JR, Stone A, Schichman S, Milberg W, McGlinchey R, Miller MW. The PPM1F gene moderates the association between PTSD and cortical thickness. J Affect Disord. 2019 12 01; 259:201-209.
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Lantrip C, Delaloye S, Baird L, Dreyer-Oren S, Brady RE, Roth RM, Gunning F, Holtzheimer P. Effects of Left Versus Right Dorsolateral Prefrontal Cortex Repetitive Transcranial Magnetic Stimulation on Affective Flexibility in Healthy Women: A Pilot Study. Cogn Behav Neurol. 2019 06; 32(2):69-75.
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Asp EW, Gullickson JT, Warner KA, Koscik TR, Denburg NL, Tranel D. Soft on crime: Patients with ventromedial prefrontal cortex damage allocate reduced third-party punishment to violent criminals. Cortex. 2019 10; 119:33-45.
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Elton A, Dove S, Spencer CN, Robinson DL, Boettiger CA. Naltrexone Acutely Enhances Connectivity Between the Ventromedial Prefrontal Cortex and a Left Frontoparietal Network. Alcohol Clin Exp Res. 2019 05; 43(5):965-978.
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Addicott MA, Luber B, Nguyen D, Palmer H, Lisanby SH, Appelbaum LG. Low- and High-Frequency Repetitive Transcranial Magnetic Stimulation Effects on Resting-State Functional Connectivity Between the Postcentral Gyrus and the Insula. Brain Connect. 2019 05; 9(4):322-328.
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Shao Z, Noh H, Bin Kim W, Ni P, Nguyen C, Cote SE, Noyes E, Zhao J, Parsons T, Park JM, Zheng K, Park JJ, Coyle JT, Weinberger DR, Straub RE, Berman KF, Apud J, Ongur D, Cohen BM, McPhie DL, Rapoport JL, Perlis RH, Lanz TA, Xi HS, Yin C, Huang W, Hirayama T, Fukuda E, Yagi T, Ghosh S, Eggan KC, Kim HY, Eisenberg LM, Moghadam AA, Stanton PK, Cho JH, Chung S. Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nat Neurosci. 2019 02; 22(2):229-242.
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Padala KP, Hunter CR, Parkes CM, Lensing SY, Padala PR. Repetitive Transcranial Magnetic Stimulation Improves Executive Function and Music Rhythm. J Neuropsychiatry Clin Neurosci. 2019 Spring; 31(2):178-180.
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Kaiser RH, Treadway MT, Wooten DW, Kumar P, Goer F, Murray L, Beltzer M, Pechtel P, Whitton A, Cohen AL, Alpert NM, El Fakhri G, Normandin MD, Pizzagalli DA. Frontostriatal and Dopamine Markers of Individual Differences in Reinforcement Learning: A Multi-modal Investigation. Cereb Cortex. 2018 12 01; 28(12):4281-4290.
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Martins BS, C?ceda R, Cisler JM, Kilts CD, James GA. The neural representation of the association between comorbid drug use disorders and childhood maltreatment. Drug Alcohol Depend. 2018 11 01; 192:215-222.
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Sadeh N, Spielberg JM, Logue MW, Hayes JP, Wolf EJ, McGlinchey RE, Milberg WP, Schichman SA, Stone A, Miller MW. Linking genes, circuits, and behavior: network connectivity as a novel endophenotype of externalizing. Psychol Med. 2019 08; 49(11):1905-1913.
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Heyn SA, Keding TJ, Ross MC, Cisler JM, Mumford JA, Herringa RJ. Abnormal Prefrontal Development in Pediatric Posttraumatic Stress Disorder: A Longitudinal Structural and Functional Magnetic Resonance Imaging Study. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 02; 4(2):171-179.
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Kearney-Ramos TE, Dowdle LT, Lench DH, Mithoefer OJ, Devries WH, George MS, Anton RF, Hanlon CA. Transdiagnostic Effects of Ventromedial Prefrontal Cortex Transcranial Magnetic Stimulation on Cue Reactivity. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 07; 3(7):599-609.
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Robicsek O, Ene HM, Karry R, Ytzhaki O, Asor E, McPhie D, Cohen BM, Ben-Yehuda R, Weiner I, Ben-Shachar D. Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder. Schizophr Bull. 2018 02 15; 44(2):432-442.
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Sheffer CE, Bickel WK, Brandon TH, Franck CT, Deen D, Panissidi L, Abdali SA, Pittman JC, Lunden SE, Prashad N, Malhotra R, Mantovani A. Preventing relapse to smoking with transcranial magnetic stimulation: Feasibility and potential efficacy. Drug Alcohol Depend. 2018 01 01; 182:8-18.
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Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Shpyleva S, Melnyk S, Pogribny I, Katz A, Sidransky D, Kovalchuk O, Kolb B. Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice. Aging (Albany NY). 2017 07 29; 9(7):1660-1676.
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Meade CS, Addicott M, Hobkirk AL, Towe SL, Chen NK, Sridharan S, Huettel SA. Cocaine and HIV are independently associated with neural activation in response to gain and loss valuation during economic risky choice. Addict Biol. 2018 03; 23(2):796-809.
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James GA, Thostenson JD, Brown G, Carter G, Hayes H, Tripathi SP, Dobry DJ, Govindan RB, Dornhoffer JL, Williams DK, Kilts CD, Mennemeier MS. Neural activity during attentional conflict predicts reduction in tinnitus perception following rTMS. Brain Stimul. 2017 Sep - Oct; 10(5):934-943.
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Hanlon CA, Dowdle LT, Correia B, Mithoefer O, Kearney-Ramos T, Lench D, Griffin M, Anton RF, George MS. Left frontal pole theta burst stimulation decreases orbitofrontal and insula activity in cocaine users and alcohol users. Drug Alcohol Depend. 2017 09 01; 178:310-317.
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Gruber SA, Dahlgren MK, Sagar KA, Gonenc A, Norris L, Cohen BM, Ongur D, Lewandowski KE. Decreased Cingulate Cortex activation during cognitive control processing in bipolar disorder. J Affect Disord. 2017 Apr 15; 213:86-95.
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Li X, Andres A, Shankar K, Pivik RT, Glasier CM, Ramakrishnaiah RH, Zhang Y, Badger TM, Ou X. Differences in brain functional connectivity at resting state in neonates born to healthy obese or normal-weight mothers. Int J Obes (Lond). 2016 12; 40(12):1931-1934.
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Neigh GN, Nemeth CL, Kelly SD, Hardy EE, Bourke C, Stowe ZN, Owens MJ. Prenatal stress-induced increases in hippocampal von Willebrand factor expression are prevented by concurrent prenatal escitalopram. Physiol Behav. 2017 04 01; 172:24-30.
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Kovalchuk A, Rodriguez-Juarez R, Ilnytskyy Y, Byeon B, Shpyleva S, Melnyk S, Pogribny I, Kolb B, Kovalchuk O. Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection. Aging (Albany NY). 2016 04; 8(4):697-711.
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Scholten M, Govindan RB, Braun C, Bloem BR, Plewnia C, Kr?ger R, Gharabaghi A, Weiss D. Cortical correlates of susceptibility to upper limb freezing in Parkinson's disease. Clin Neurophysiol. 2016 06; 127(6):2386-93.
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Sadeh N, Spielberg JM, Logue MW, Wolf EJ, Smith AK, Lusk J, Hayes JP, Sperbeck E, Milberg WP, McGlinchey RE, Salat DH, Carter WC, Stone A, Schichman SA, Humphries DE, Miller MW. SKA2 methylation predicts reduced cortical thickness in prefrontal cortex. Mol Psychiatry. 2016 Mar; 21(3):299.
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Miller MW, Wolf EJ, Sadeh N, Logue M, Spielberg JM, Hayes JP, Sperbeck E, Schichman SA, Stone A, Carter WC, Humphries DE, Milberg W, McGlinchey R. A novel locus in the oxidative stress-related gene ALOX12 moderates the association between PTSD and thickness of the prefrontal cortex. Psychoneuroendocrinology. 2015 Dec; 62:359-65.
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Sadeh N, Spielberg JM, Logue MW, Wolf EJ, Smith AK, Lusk J, Hayes JP, Sperbeck E, Milberg WP, McGlinchey RE, Salat DH, Carter WC, Stone A, Schichman SA, Humphries DE, Miller MW. SKA2 methylation is associated with decreased prefrontal cortical thickness and greater PTSD severity among trauma-exposed veterans. Mol Psychiatry. 2016 Mar; 21(3):357-63.
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Sutterer MJ, Koscik TR, Tranel D. Sex-related functional asymmetry of the ventromedial prefrontal cortex in regard to decision-making under risk and ambiguity. Neuropsychologia. 2015 Aug; 75:265-73.
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Lewandowski KE, Ong?r D, Sperry SH, Cohen BM, Sehovic S, Goldbach JR, Du F. Myelin vs axon abnormalities in white matter in bipolar disorder. Neuropsychopharmacology. 2015 Mar 13; 40(5):1243-9.
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