Radiation-Protective Agents
"Radiation-Protective Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other, e.g. military, purposes.
Descriptor ID |
D011837
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MeSH Number(s) |
D27.505.696.706.776 D27.720.799.763
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Concept/Terms |
Radiation-Protective Agents- Radiation-Protective Agents
- Radiation Protectants
- Protectants, Radiation
- Radioprotective Drugs
- Drugs, Radioprotective
- Radiation-Protective Drugs
- Drugs, Radiation-Protective
- Radiation Protective Drugs
- Radioprotective Agents
- Agents, Radioprotective
- Agents, Radiation-Protective
- Agents, Radiation Protective
- Radiation Protective Agents
- Protective Agents, Radiation
Radiation-Protective Effect- Radiation-Protective Effect
- Effect, Radiation-Protective
- Radiation Protective Effect
- Radiation-Protective Effects
- Effects, Radiation-Protective
- Radiation Protective Effects
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Below are MeSH descriptors whose meaning is more general than "Radiation-Protective Agents".
Below are MeSH descriptors whose meaning is more specific than "Radiation-Protective Agents".
This graph shows the total number of publications written about "Radiation-Protective Agents" by people in UAMS Profiles by year, and whether "Radiation-Protective Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2024 | 1 | 0 | 1 | 2022 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2020 | 2 | 1 | 3 | 2019 | 1 | 0 | 1 | 2018 | 1 | 1 | 2 | 2016 | 3 | 0 | 3 | 2015 | 2 | 0 | 2 | 2013 | 3 | 2 | 5 | 2012 | 2 | 0 | 2 | 2011 | 1 | 0 | 1 | 2010 | 2 | 0 | 2 | 2009 | 3 | 0 | 3 | 2008 | 0 | 1 | 1 | 2007 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 1993 | 1 | 0 | 1 | 1990 | 2 | 1 | 3 |
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Below are the most recent publications written about "Radiation-Protective Agents" by people in Profiles over the past ten years.
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Singh VK, Wise SY, Fatanmi OO, Petrus SA, Carpenter AD, Lee SH, Hauer-Jensen M, Seed TM. Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol. Sci Rep. 2024 03 08; 14(1):5757.
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Garg TK, Garg S, Miousse IR, Wise SY, Carpenter AD, Fatanmi OO, van Rhee F, Singh VK, Hauer-Jensen M. Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation. Radiat Res. 2024 01 01; 201(1):55-70.
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Garg S, Garg TK, Wise SY, Fatanmi OO, Miousse IR, Savenka AV, Basnakian AG, Singh VK, Hauer-Jensen M. Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate. Int J Mol Sci. 2022 Apr 22; 23(9).
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Nemec-Bakk AS, Sridharan V, Landes RD, Singh P, Cao M, Seawright JW, Liu X, Zheng G, Dominic P, Pathak R, Boerma M. Mitigation of late cardiovascular effects of oxygen ion radiation by ?-tocotrienol in a mouse model. Life Sci Space Res (Amst). 2021 Nov; 31:43-50.
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Corry PM, Griffin RJ. A Radiation Mitigator as a Potential Treatment for COVID-19. Radiat Res. 2020 06 01; 193(6):505.
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Liu X, Gao Z, Fu Q, Song L, Zhang P, Zhang X, Hendrickson H, Crooks PA, Zhou D, Zheng G. Deuteration of the farnesyl terminal methyl groups of d-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production. Bioorg Med Chem. 2020 06 01; 28(11):115498.
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McElroy T, Brown T, Kiffer F, Wang J, Byrum SD, Oberley-Deegan RE, Allen AR. Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment. Int J Mol Sci. 2020 Mar 09; 21(5).
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Aykin-Burns N, Pathak R, Boerma M, Kim T, Hauer-Jensen M. Utilization of Vitamin E Analogs to Protect Normal Tissues While Enhancing Antitumor Effects. Semin Radiat Oncol. 2019 01; 29(1):55-61.
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Landes RD, Lensing SY, Hauer-Jensen M. Interval estimators of relative potency in toxicology and radiation countermeasure studies: comparing methods and experimental designs. J Biopharm Stat. 2019; 29(2):348-358.
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Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. Radiat Res. 2018 11; 190(5):449-463.
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Singh VK, Hauer-Jensen M. ?-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. Int J Mol Sci. 2016 May 03; 17(5).
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Ghosh SP, Pathak R, Kumar P, Biswas S, Bhattacharyya S, Kumar VP, Hauer-Jensen M, Biswas R. Gamma-Tocotrienol Modulates Radiation-Induced MicroRNA Expression in Mouse Spleen. Radiat Res. 2016 05; 185(5):485-95.
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Singh VK, Kulkarni S, Fatanmi OO, Wise SY, Newman VL, Romaine PL, Hendrickson H, Gulani J, Ghosh SP, Kumar KS, Hauer-Jensen M. Radioprotective Efficacy of Gamma-Tocotrienol in Nonhuman Primates. Radiat Res. 2016 Mar; 185(3):285-98.
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Hye Khan MA, Fish B, Wahl G, Sharma A, Falck JR, Paudyal MP, Moulder JE, Imig JD, Cohen EP. Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy. Clin Sci (Lond). 2016 Apr; 130(8):587-99.
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Singh VK, Newman VL, Romaine PL, Hauer-Jensen M, Pollard HB. Use of biomarkers for assessing radiation injury and efficacy of countermeasures. Expert Rev Mol Diagn. 2016; 16(1):65-81.
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Pathak R, Shao L, Ghosh SP, Zhou D, Boerma M, Weiler H, Hauer-Jensen M. Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice. PLoS One. 2015; 10(4):e0122511.
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Sridharan V, Tripathi P, Aykin-Burns N, Krager KJ, Sharma SK, Moros EG, Melnyk SB, Pavliv O, Hauer-Jensen M, Boerma M. A tocotrienol-enriched formulation protects against radiation-induced changes in cardiac mitochondria without modifying late cardiac function or structure. Radiat Res. 2015 Mar; 183(3):357-66.
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