Centrosome
"Centrosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous material called the pericentriolar region. During interphase, the centrosome nucleates microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).
Descriptor ID |
D018385
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MeSH Number(s) |
A11.284.430.214.190.750.585.160
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Concept/Terms |
Pericentriolar Region- Pericentriolar Region
- Pericentriolar Regions
- Region, Pericentriolar
- Regions, Pericentriolar
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Below are MeSH descriptors whose meaning is more general than "Centrosome".
Below are MeSH descriptors whose meaning is more specific than "Centrosome".
This graph shows the total number of publications written about "Centrosome" by people in UAMS Profiles by year, and whether "Centrosome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2016 | 2 | 0 | 2 | 2015 | 1 | 1 | 2 | 2014 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2008 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Centrosome" by people in Profiles over the past ten years.
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Ho SM, Rao R, To S, Schoch E, Tarapore P. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer. 2017 02; 24(2):83-96.
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El Bissati K, Suvorova ES, Xiao H, Lucas O, Upadhya R, Ma Y, Angeletti RH, White MW, Weiss LM, Kim K. Toxoplasma gondii Arginine Methyltransferase 1 (PRMT1) Is Necessary for Centrosome Dynamics during Tachyzoite Cell Division. mBio. 2016 Feb 02; 7(1):e02094-15.
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Penthala NR, Crooks PA, Freeman ML, Sekhar KR. Development and validation of a novel assay to identify radiosensitizers that target nucleophosmin 1. Bioorg Med Chem. 2015 Jul 01; 23(13):3681-6.
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Suvorova ES, Francia M, Striepen B, White MW. A novel bipartite centrosome coordinates the apicomplexan cell cycle. PLoS Biol. 2015 Mar; 13(3):e1002093.
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