 beta Karyopherins
"beta Karyopherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
| Descriptor ID |
D028961
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| MeSH Number(s) |
D12.776.157.530.750.500.249 D12.776.543.585.750.500.249 D12.776.660.502.500
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| Concept/Terms |
beta Karyopherins- beta Karyopherins
- Karyopherins, beta
- Kap95 protein
- p92 nuclear protein
- nuclear protein, p92
- beta Importins
- Importins, beta
- Karyopherin-beta
- Karyopherin-beta Subunit
- Karyopherin beta Subunit
- Importin-beta
- Importin beta
- Karyopherin beta
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Below are MeSH descriptors whose meaning is more general than "beta Karyopherins".
Below are MeSH descriptors whose meaning is more specific than "beta Karyopherins".
This graph shows the total number of publications written about "beta Karyopherins" by people in UAMS Profiles by year, and whether "beta Karyopherins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta Karyopherins" by people in Profiles over the past ten years.
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Chi RA, van der Watt P, Wei W, Birrer MJ, Leaner VD. Inhibition of Kpn?1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer. BMC Cancer. 2021 Feb 02; 21(1):106.
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Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P. miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. Cell Rep. 2019 12 24; 29(13):4389-4406.e10.
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van der Watt PJ, Chi A, Stelma T, Stowell C, Strydom E, Carden S, Angus L, Hadley K, Lang D, Wei W, Birrer MJ, Trent JO, Leaner VD. Targeting the Nuclear Import Receptor Kpn?1 as an Anticancer Therapeutic. Mol Cancer Ther. 2016 04; 15(4):560-73.
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