Multifactorial Inheritance
"Multifactorial Inheritance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenotypic outcome (physical characteristic or disease predisposition) that is determined by more than one gene. Polygenic refers to those determined by many genes, while oligogenic refers to those determined by a few genes.
Descriptor ID |
D020412
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MeSH Number(s) |
G05.420.590
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Concept/Terms |
Multifactorial Inheritance- Multifactorial Inheritance
- Inheritance, Multifactorial
- Inheritances, Multifactorial
- Multifactorial Inheritances
Polygenic Inheritance- Polygenic Inheritance
- Inheritance, Polygenic
- Inheritances, Polygenic
- Polygenic Inheritances
- Polygenic Traits
- Polygenic Trait
- Trait, Polygenic
- Traits, Polygenic
- Polygenic Characters
- Character, Polygenic
- Characters, Polygenic
- Polygenic Character
Oligogenic Inheritance- Oligogenic Inheritance
- Inheritance, Oligogenic
- Inheritances, Oligogenic
- Oligogenic Inheritances
- Oligogenic Traits
- Oligogenic Trait
- Trait, Oligogenic
- Traits, Oligogenic
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Below are MeSH descriptors whose meaning is more general than "Multifactorial Inheritance".
Below are MeSH descriptors whose meaning is more specific than "Multifactorial Inheritance".
This graph shows the total number of publications written about "Multifactorial Inheritance" by people in UAMS Profiles by year, and whether "Multifactorial Inheritance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2023 | 0 | 2 | 2 | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Multifactorial Inheritance" by people in Profiles over the past ten years.
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Frye RE. Editorial: Mitochondrial Gene Variations Increase Autism Risk: Uncovering the Complex Polygenetic Landscape of Autism. J Am Acad Child Adolesc Psychiatry. 2024 Aug; 63(8):775-777.
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Miner SA, Pereira S. The Need for Diverse Empirical Data to Inform the Use of Polygenic Risk Scores in Prenatal Screening. Am J Bioeth. 2023 03; 23(3):39-41.
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Howe LJ, Evans DM, Hemani G, Davey Smith G, Davies NM. Evaluating indirect genetic effects of siblings using singletons. PLoS Genet. 2022 07; 18(7):e1010247.
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Howe LJ, Tudball M, Davey Smith G, Davies NM. Interpreting Mendelian-randomization estimates of the effects of categorical exposures such as disease status and educational attainment. Int J Epidemiol. 2022 06 13; 51(3):948-957.
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Howe LJ, Nivard MG, Morris TT, Hansen AF, Rasheed H, Cho Y, Chittoor G, Ahlskog R, Lind PA, Palviainen T, van der Zee MD, Cheesman R, Mangino M, Wang Y, Li S, Klaric L, Ratliff SM, Bielak LF, Nygaard M, Giannelis A, Willoughby EA, Reynolds CA, Balbona JV, Andreassen OA, Ask H, Baras A, Bauer CR, Boomsma DI, Campbell A, Campbell H, Chen Z, Christofidou P, Corfield E, Dahm CC, Dokuru DR, Evans LM, de Geus EJC, Giddaluru S, Gordon SD, Harden KP, Hill WD, Hughes A, Kerr SM, Kim Y, Kweon H, Latvala A, Lawlor DA, Li L, Lin K, Magnus P, Magnusson PKE, Mallard TT, Martikainen P, Mills MC, Nj?lstad PR, Overton JD, Pedersen NL, Porteous DJ, Reid J, Silventoinen K, Southey MC, Stoltenberg C, Tucker-Drob EM, Wright MJ, Hewitt JK, Keller MC, Stallings MC, Lee JJ, Christensen K, Kardia SLR, Peyser PA, Smith JA, Wilson JF, Hopper JL, H?gg S, Spector TD, Pingault JB, Plomin R, Havdahl A, Bartels M, Martin NG, Oskarsson S, Justice AE, Millwood IY, Hveem K, Naess ?, Willer CJ, ?svold BO, Koellinger PD, Kaprio J, Medland SE, Walters RG, Benjamin DJ, Turley P, Evans DM, Davey Smith G, Hayward C, Brumpton B, Hemani G, Davies NM. Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects. Nat Genet. 2022 05; 54(5):581-592.
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Arsenault SV, King JT, Kay S, Lacy KD, Ross KG, Hunt BG. Simple inheritance, complex regulation: Supergene-mediated fire ant queen polymorphism. Mol Ecol. 2020 10; 29(19):3622-3636.
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Howe LJ, Hemani G, Lesseur C, Gaborieau V, Ludwig KU, Mangold E, Brennan P, Ness AR, St Pourcain B, Davey Smith G, Lewis SJ. Evaluating shared genetic influences on nonsyndromic cleft lip/palate and oropharyngeal neoplasms. Genet Epidemiol. 2020 11; 44(8):924-933.
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Howe LJ, Dudbridge F, Schmidt AF, Finan C, Denaxas S, Asselbergs FW, Hingorani AD, Patel RS. Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases. Hum Mol Genet. 2020 05 28; 29(8):1388-1395.
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Xiong Z, Dankova G, Howe LJ, Lee MK, Hysi PG, de Jong MA, Zhu G, Adhikari K, Li D, Li Y, Pan B, Feingold E, Marazita ML, Shaffer JR, McAloney K, Xu SH, Jin L, Wang S, de Vrij FM, Lendemeijer B, Richmond S, Zhurov A, Lewis S, Sharp GC, Paternoster L, Thompson H, Gonzalez-Jose R, Bortolini MC, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Uitterlinden AG, Ikram MA, Wolvius E, Kushner SA, Nijsten TE, Palstra RT, Boehringer S, Medland SE, Tang K, Ruiz-Linares A, Martin NG, Spector TD, Stergiakouli E, Weinberg SM, Liu F, Kayser M. Novel genetic loci affecting facial shape variation in humans. Elife. 2019 11 26; 8.
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Lawson DJ, Davies NM, Haworth S, Ashraf B, Howe L, Crawford A, Hemani G, Davey Smith G, Timpson NJ. Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity? Hum Genet. 2020 Jan; 139(1):23-41.
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Howe LJ, Lee MK, Sharp GC, Davey Smith G, St Pourcain B, Shaffer JR, Ludwig KU, Mangold E, Marazita ML, Feingold E, Zhurov A, Stergiakouli E, Sandy J, Richmond S, Weinberg SM, Hemani G, Lewis SJ. Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology. PLoS Genet. 2018 08; 14(8):e1007501.
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Musci RJ, Fairman B, Masyn KE, Uhl G, Maher B, Sisto DY, Kellam SG, Ialongo NS. Polygenic Score ? Intervention Moderation: an Application of Discrete-Time Survival Analysis to Model the Timing of First Marijuana Use Among Urban Youth. Prev Sci. 2018 01; 19(1):6-14.
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Wolf EJ, Miller DR, Logue MW, Sumner J, Stoop TB, Leritz EC, Hayes JP, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Miller MW. Contributions of polygenic risk for obesity to PTSD-related metabolic syndrome and cortical thickness. Brain Behav Immun. 2017 Oct; 65:328-336.
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Miller DR, Logue MW, Wolf EJ, Maniates H, Robinson ME, Hayes JP, Stone A, Schichman S, McGlinchey RE, Milberg WP, Miller MW. Posttraumatic stress disorder symptom severity is associated with reduced default mode network connectivity in individuals with elevated genetic risk for psychopathology. Depress Anxiety. 2017 07; 34(7):632-640.
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