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Joseph Margolick

CredentialsArkansas State Medical License E13203
Texas State Medical License S4814
Fellow of Royal College of Surgeons of Canada
TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCOM | Surgery Trauma Surgery
DivisionSurgery Trauma Surgery
Address324 UAMS Campus Dr.
Mail Slot # 520-1
Little Rock AR 72205
ORCID ORCID Icon0000-0002-4210-9093 Additional info
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    Collapse Affiliation 
    Collapse clinical activities
    Surgical ICU Physician
    Trauma Surgeon
    General Surgeon
    ECMO Physician
    Endoscopy
    Assistant Professor

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    LITES Trauma Research Network. UAMS site principal investigator

    Collapse education and training
    Western University, London ON CanadaBA06/2009Biology and Psychology
    McMaster University, London ON CanadaMD05/2014Doctor of Medicine
    University of British Columbia, Vancouver BC Canada06/2019General Surgery Residency
    University of Texas Southwestern, Dallas TX07/2020Trauma and Critical Care Fellowship
    Collapse awards and honors
    2018 - 2019General Surgery Resident Teaching Award, Canadian Association of General Surgeons
    2017Research Award $4900, University of British Columbia

    Collapse Research 
    Collapse research activities and funding
    4600053346     (DAVIS, BENJAMIN)Jul 1, 2023 - Jun 30, 2024
    Arkansas Department of Health
    FY2024 Hospital Trauma Grant
    Role: Principal Investigator
    4600051704     (ROBERTSON, RONALD D)Sep 2, 2022 - Jun 30, 2023
    Arkansas Department of Health
    FY2023 Hospital Trauma Center Grant
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Bourgi K, Bian A, Boyd L, Gupta SK, Cohen C, Lee JC, Sterling TR, Moore RD, Lesko C, Lake JE, Yendewa GA, Horberg MA, Silverberg MJ, Palella FJ, Althoff K, Margolick J, Rebeiro PR, Koethe JR. Weight Gain on Contemporary Integrase Strand Transfer Inhibitors and Tenofovir Alafenamide in Persons with HIV Starting Antiretroviral Therapy in the United States and Canada. J Infect Dis. 2026 May 29. PMID: 42216675.
      View in: PubMed
    2. Byun JY, Jones R, Iriarte E, Xavier Hall CD, Krause KD, Wang CX, Pahwa S, Lam JO, Falutz J, Masters MC, Corley M, Marzolini C, Greene M, Vera J, Siegler EL, Margolick JB, Ellis RJ, Letendre S, Moore DJ. Current perspectives and emerging directions in research and practice: highlights from the 15th Annual International Workshop on Aging and HIV. J Gerontol A Biol Sci Med Sci. 2026 May 07; 81(6). PMID: 41872027.
      View in: PubMed
    3. Peterson TE, Hahn VS, Moaddel R, Zhu M, Fan J, De S, Haberlen SA, Palella FJ, Plankey M, Bader JS, Lima JAC, Gerszten RE, Rotter JI, Kirk GD, Piggott DA, Ferrucci L, Margolick JB, Brown TT, Post WS, Wu KC. Human Immunodeficiency Virus-Associated Proteomic Signature of Myocardial Fibrosis and Incident Heart Failure. J Infect Dis. 2026 Apr 29; 233(4):e937-e947. PMID: 41521844.
      View in: PubMed
    4. Abraham AG, Guo X, Lawa S, Mihailovic A, Plankey MW, Brown TT, Margolick JB, Ramulu P, Banerjee S. Eye Health and Vision Function in Adults Aging with Well-Controlled HIV. Viruses. 2026 Apr 02; 18(4). PMID: 42043220.
      View in: PubMed
    5. Fisher MC, Hanna DB, Hoover DR, Shi Q, Sharma A, Estrella MM, Brown TT, Floris-Moore M, Palella FJ, Lake JE, Kassaye SG, Koletar SL, Seaberg EC, Margolick JB, Ofotokun I, Hickman A, Augenbraun M, Fischl M, Landay AL, Kaplan RC, Ross MJ. Serum Biomarkers of Macrophage Activation and Incident CKD in People With and Without HIV: Findings From the MACS-WIHS Combined Cohort Study. Open Forum Infect Dis. 2026 Apr; 13(4):ofag147. PMID: 41940005.
      View in: PubMed
    6. Punjabi NM, Brown TT, Stefanovski D, Aurora RN, Patel SR, Stosor V, Cho JH, D'Souza G, Margolick JB. Differences in sleep architecture between men living with and without HIV. Sleep. 2025 Dec 11; 48(12). PMID: 41081781.
      View in: PubMed
    7. Nowell AB, Wells AA, Bailey BJ, Jensen HK, Smith RR, Jenkins AK, Betzold RD, Margolick JF, Kalkwarf KJ. Opioid Administration in a Surgical Intensive Care Unit: Association of Persistent Opioid Use. Am Surg. 2026 May; 92(5):1473-1475. PMID: 41232045.
      View in: PubMed
    8. Wojcik G, Arvanitis M, Haberlen S, Kim EY, Kim H, Nam K, Feinstein MJ, Wolinsky S, Margolick JB, Budoff M, Magnani JW, Duggal P, Post WS. Differential Performance of Polygenic Score for Coronary Artery Disease Based on Coronary Artery Calcium Between Men Living With and Without HIV. J Am Heart Assoc. 2025 Nov 18; 14(22):e045144. PMID: 41220122.
      View in: PubMed
    9. Pan Y, Musselman D, Mithani Z, Tong W, Margolick J, Palella FJ, Mimiaga MJ, Bodnar K, Konkle-Parker D, Wingood G, Westreich D, Seaberg E, Lauren S, Cohen M, Estrella MM, Spence A, Wilson T, Ross M, Feaster D, Alcaide ML, Jones DL. HIV, Nephrotoxic Medications, and Chronic Kidney Disease: Prevalence, Risk Factors, and Mediation Analyses Among People With and Without HIV Enrolled in the Multicenter AIDS Cohort Study (MACS) / Women's Interagency HIV Study (WIHS) Combined Cohort Study. medRxiv. 2025 Nov 06. PMID: 41282841.
      View in: PubMed
    10. Fisher MC, Scherzer R, Postalcioglu M, Chen TK, Ascher SB, Lake JE, Floris-Morre M, Kassaye S, Ofotokun I, Dionne J, Alcaide M, Cohen M, Gustafson D, Abraham AG, Margolick JB, Ho K, Stosor V, Tien PC, Shlipak M, Estrella MM. Associations of repeated measures of plasma biomarkers of kidney tubular health with longitudinal kidney function in people with HIV. AIDS. 2026 Feb 01; 40(2):160-169. PMID: 40996694.
      View in: PubMed
    11. Reeves DB, Rigau DN, Romero A, Zhang H, Simonetti FR, Varriale J, Hoh R, Zhang L, Smith KN, Montaner LJ, Rubin LH, Gange SJ, Roan NR, Tien PC, Margolick JB, Peluso MJ, Deeks SG, Schiffer JT, Siliciano JD, Siliciano RF, Antar AAR. Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells. Cell Syst. 2025 Oct 15; 16(10):101402. PMID: 40987290.
      View in: PubMed
    12. Zhang W, Scott AF, Mohr DW, Ingersoll R, Shoucair PE, Bream JH, Nilles TL, Zhang H, Chen Y, Mailliard RB, Margolick JB. Complete CD16A Deficiency and Defective NK Cell Function in a Man Living with HIV. J Clin Immunol. 2025 May 24; 45(1):98. PMID: 40411624.
      View in: PubMed
    13. Whelton SP, Haberlen SA, Zhang L, Herrschaft R, Witt MD, Jacobson LP, Margolick JB, Magnani JW, Palella FJ, Brown TT, Budoff M, Post WS. Associations between HIV serostatus and coronary artery plaque volume progression. AIDS. 2025 Feb 25. PMID: 39998603.
      View in: PubMed
    14. Peterson TE, Hahn VS, Moaddel R, Zhu M, Haberlen SA, Palella FJ, Plankey M, Bader JS, Lima JAC, Gerszten RE, Rotter JI, Rich SS, Heckbert SR, Kirk GD, Piggott DA, Ferrucci L, Margolick JB, Brown TT, Wu KC, Post WS. Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure. Nat Commun. 2025 Jan 12; 16(1):610. PMID: 39800750.
      View in: PubMed
    15. Baim-Lance A, Cooley S, Yoo-Jeong M, Ances B, Duque G, Ellis RJ, Flexner C, Pence BW, Plankey M, Mullins JD, Sun J, Thames AD, Margolick JB, Moore DJ, Erlandson KM. Current Challenges, Solutions, and Novel Directions in Research and Clinical Care: Proceedings From the 14th Annual International Workshop on HIV and Aging. J Gerontol A Biol Sci Med Sci. 2024 Dec 11; 80(1). PMID: 39492669.
      View in: PubMed
    16. Zhang W, Nilles TL, Bream JH, Li H, Malash E, Langan S, Leng SX, Margolick JB. Breadth and polyfunctionality of T cell responses to human cytomegalovirus in men who have sex with men: relationship with HIV infection and frailty. J Virol. 2024 Oct 22; 98(10):e0116724. PMID: 39230302.
      View in: PubMed
    17. Raju S, Siddharthan T, McCormack MC, Patel SR, Kunisaki KM, D'Souza G, Cho JH, Stosor V, Morris A, Margolick JB, Brown TT, Punjabi NM. Influence of Impaired Diffusing Capacity and Sleep-disordered Breathing on Nocturnal Hypoxemia and Health Outcomes in Men with and without Human Immunodeficiency Virus. Ann Am Thorac Soc. 2024 Jul; 21(7):1085-1093. PMID: 38498872.
      View in: PubMed
    18. Lake JE, Feng H, Hyatt AN, Miao H, Debroy P, Funderburg N, Ailstock K, Dobs A, Haberlen S, Magnani JW, Margolick JB, McGowan K, Palella FJ, Witt MD, Bhasin S, Budoff MJ, Post WS, Brown TT. Transgender Women With Suppressed Testosterone Display Lower Burden of Coronary Disease Than Matched Cisgender Men. J Endocr Soc. 2024 Jul 01; 8(8):bvae120. PMID: 38974987.
      View in: PubMed
    19. Kalkwarf KJ, Bailey BJ, Wells A, Jenkins AK, Smith RR, Greer JW, Yeager R, Bruce N, Margolick J, Kost MR, Kimbrough MK, Roberts ML, Davis BL, Privratsky A, Curran GM. Using implementation science to decrease variation and high opioid administration in a surgical ICU. J Trauma Acute Care Surg. 2024 Nov 01; 97(5):716-723. PMID: 38685205.
      View in: PubMed
    20. Wade DJ, Pilkington C, Henson JC, Jensen HK, Kalkwarf K, Bhavaraju A, Bruce N, Bowman S, Margolick J. Higher Doses of Calcium Associated With Survival in Trauma Patients. J Surg Res. 2024 Nov; 303:788-794. PMID: 38519359.
      View in: PubMed
    21. Moore B, Jensen H, Patel K, Modi Z, Reif RJ, Lal S, Bowman SM, Kost M, Kalkwarf KJ, Margolick J, Bhavaraju A, Corwin HL. Outcomes of trauma patients on chronic antithrombotic therapies in a trauma center in a rural state. Surg Pract Sci. 2023 Dec; 15:100221. PMID: 39844808.
      View in: PubMed
    22. Dumas RP, Vella MA, Maiga AW, Erickson CR, Dennis BM, da Luz LT, Pannell D, Quigley E, Velopulos CG, Hendzlik P, Marinica A, Bruce N, Margolick J, Butler DF, Estroff J, Zebley JA, Alexander A, Mitchell S, Grossman Verner HM, Truitt M, Berry S, Middlekauff J, Luce S, Leshikar D, Krowsoski L, Bukur M, Polite NM, McMann AH, Staszak R, Armen SB, Horrigan T, Moore FO, Bjordahl P, Guido J, Mathew S, Diaz BF, Mooney J, Hebeler K, Holena DN. Moving the needle on time to resuscitation: An EAST prospective multicenter study of vascular access in hypotensive injured patients using trauma video review. J Trauma Acute Care Surg. 2023 07 01; 95(1):87-93. PMID: 37012624.
      View in: PubMed
    23. Lin SH, Khan SM, Zhou W, Brown DW, Vergara C, Wolinsky SM, Mart?nez-Maza O, Margolick JB, Martinson JJ, Hussain SK, Engels EA, Machiela MJ. Mosaic chromosomal alterations detected in men living with HIV and the relationship to non-Hodgkin lymphoma. AIDS. 2023 07 01; 37(8):1307-1313. PMID: 36927626.
      View in: PubMed
    24. Yu X, Lobo JD, Sundermann E, Baker DJ, Tracy RP, Kuchel GA, Stephenson KE, Letendre SL, Brew B, Cysique LA, Dale SK, Wallen C, Kunisaki KM, Guaraldi G, Milic J, Winston A, Moore DJ, Margolick JB, Erlandson KM. Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop. AIDS Res Hum Retroviruses. 2023 01; 39(1):1-12. PMID: 36322713.
      View in: PubMed
    25. Punjabi NM, Brown TT, Aurora RN, Patel SR, Stosor V, Hyong-Jin Cho J, D'Souza G, Margolick JB. Prevalence and Predictors of Sleep-Disordered Breathing in Men Participating in the Multicenter AIDS Cohort Study. Chest. 2023 03; 163(3):687-696. PMID: 36343689.
      View in: PubMed
    26. Peterson TE, Landon C, Haberlen SA, Bhondoekhan F, Plankey MW, Palella FJ, Piggott DA, Margolick JB, Brown TT, Post WS, Wu KC. Circulating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIV. BMC Cardiovasc Disord. 2022 09 03; 22(1):393. PMID: 36057773.
      View in: PubMed
    27. Wang S, Pasca S, Post WS, Langan S, Pallavajjala A, Haley L, Gocke CD, Budoff M, Haberlen S, Brown TT, Ambinder RF, Margolick JB, Gondek LP. Clonal hematopoiesis in men living with HIV and association with subclinical atherosclerosis. AIDS. 2022 09 01; 36(11):1521-1531. PMID: 35730391.
      View in: PubMed
    28. Wada NI, Breen EC, Post WS, Stosor V, Macatangay BJ, Margolick JB. Long-term Trajectories of C-Reactive Protein Among Men Living With and Without HIV Infection in the Multicenter AIDS Cohort Study. J Gerontol A Biol Sci Med Sci. 2022 07 05; 77(7):1382-1388. PMID: 34223896.
      View in: PubMed
    29. Punjabi NM, Brown T, Aurora RN, Patel SR, Stosor V, Cho JH, Helgad?ttir H, ?g?stsson JS, D'Souza G, Margolick JB. Methods for home-based self-applied polysomnography: the Multicenter AIDS Cohort Study. Sleep Adv. 2022; 3(1):zpac011. PMID: 35601080.
      View in: PubMed
    30. Post WS, Haberlen SA, Witt MD, Zhang L, Jacobson LP, Brown TT, Margolick JB, Kingsley L, Palella FJ, Budoff M. Suboptimal HIV suppression is associated with progression of coronary artery stenosis: The Multicenter AIDS Cohort Study (MACS) longitudinal coronary CT angiography study. Atherosclerosis. 2022 07; 353:33-40. PMID: 35577614.
      View in: PubMed
    31. Klutts G, Kalkwarf K, Meyer D, Yang Y, Wolf DA, Bhavaraju A, Margolick J, Marino K, Robertson R, Drake SA. An Analysis of Traumatic and Non-Traumatic Hemopericardium Using Autopsy Data From a County Medical Examiner. Am Surg. 2022 Aug; 88(8):1909-1911. PMID: 35430907.
      View in: PubMed
    32. Dickinson KJ, Kimbrough MK, Young A, Goddard C, Urban K, Kalkwarf KJ, Bhavaraju A, Margolick J. An Educational Module to Teach Interprofessional Learner Feedback Skills for Trauma Simulation Events. World J Surg. 2022 07; 46(7):1602-1608. PMID: 35397676.
      View in: PubMed
    33. Dickinson KJ, Kimbrough MK, Young A, Goddard C, Urban K, Kalkwarf KJ, Bhavaraju A, Margolick J. The community of inquiry framework for virtual team-to-team debriefings during interprofessional trauma simulations. Global Surg Educ. 2022; 1(1):11. PMID: 38624909.
      View in: PubMed
    34. Zhang W, Li H, Bream JH, Nilles TL, Leng SX, Margolick JB. Longitudinal association of cytokine-producing CMV-specific T cells with frailty in HIV-infected and -uninfected men who have sex with men. Immun Ageing. 2022 Mar 07; 19(1):13. PMID: 35255947.
      View in: PubMed
    35. Mashayekhi A, Quiroga EF, Margolick JF, Post GR. Intestinal T-cell lymphoma: A rare entity presenting with severe acute upper quadrant pain. Clin Case Rep. 2022 Mar; 10(3):e05546. PMID: 35280095.
      View in: PubMed
    36. Zhang F, Sun L, Lafferty MK, Margolick JB, Garzino-Demo A. Decreased MIP-3a Production from Antigen-Activated PBMCs in Symptomatic HIV-Infected Subjects. Pathogens. 2021 Dec 22; 11(1). PMID: 35055955.
      View in: PubMed
    37. Kaddour H, Kopcho S, Lyu Y, Shouman N, Paromov V, Pratap S, Dash C, Kim EY, Martinson J, McKay H, Epeldegui M, Margolick JB, Stapleton JT, Okeoma CM. HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network. Cell Mol Life Sci. 2021 Dec 22; 79(1):5. PMID: 34936021.
      View in: PubMed
    38. Chen Y, Lin H, Cole M, Morris A, Martinson J, Mckay H, Mimiaga M, Margolick J, Fitch A, Methe B, Srinivas VR, Peddada S, Rinaldo CR. Signature changes in gut microbiome are associated with increased susceptibility to HIV-1 infection in MSM. Microbiome. 2021 12 09; 9(1):237. PMID: 34879869.
      View in: PubMed
    39. Gongola A, Bradshaw JC, Jin J, Jensen HK, Bhavaraju A, Margolick J, Sexton KW, Robertson R, Kalkwarf KJ. Retrospective study on rib fractures: smoking and alcohol matter for mortality and complications. Trauma Surg Acute Care Open. 2021; 6(1):e000732. PMID: 34212116.
      View in: PubMed
    40. Walker A, Bonham VL, Boyce A, Clayton EW, Garcia D, Johnson S, Laeyendecker O, Lewis M, Margolick JB, Mathews D, Parker MJ, Spicer P, Thio CL, Geller G, Kahn J. Ethical Issues in Genetics and Infectious Diseases Research: An Interdisciplinary Expert Review. Ethics Med Public Health. 2021 Sep; 18. PMID: 34263019.
      View in: PubMed
    41. AlleaBelle Gongola, Jace C. Bradshaw, Jing Jin, Hanna K Jensen, Avi Bhavaraju, Joseph Margolick, Kevin W. Sexton, Ronald Robretson, Kyle J. Kalkwarf. Trauma Surgery Acute Care Open. Retrospective Study on Rib Fractures: Smoking and Alcohol Matter for Mortality and Complications. 2021; (6):1-6.
    42. Joseph Margolick. UAMS Department of Surgery Guidelines: Surgical Site Infection Reduction Bundle. 2021.
    43. Jedrzejko N, Margolick J, Nguyen JH, Ding M, Kisa P, Ball-Banting E, Hameed M, Joos E. A systematic review of global surgery partnerships and a proposed framework for sustainability. Can J Surg. 2021 04 28; 64(3):E280-E288. PMID: 33908733.
      View in: PubMed
    44. Joseph Margolick. UAMS Department of Surgery Guidelines: Acute Pelvic Fracture Management. 2020.
    45. JR Taylor, Joseph Margolick. UAMS Department of Surgery Guidelines: Blunt Cerebrovascular Injury Screening and Treatment. 2020.
    46. Margolick J, Yin L, Joharifard S, Afya A, Velez MLAM, Meza E, Sohani S, Laane C, Ball-Banting E, Joos E. Acute care surgery, trauma and disaster relief: a clinical exchange between the University of British Columbia and the Mexican Red Cross. Can J Surg. 2020 07 09; 63(4):E338-E345. PMID: 32644319.
      View in: PubMed
    47. Margolick J, Dandurand C, Duncan K, Chen W, Evans DC, Sekhon MS, Garraway N, Griesdale DEG, Gooderham P, Hameed SM. A Systematic Review of the Risks and Benefits of Venous Thromboembolism Prophylaxis in Traumatic Brain Injury. Can J Neurol Sci. 2018 07; 45(4):432-444. PMID: 29895339.
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    48. Margolick J, Chen W, Wiseman SM. Systematic Review and Meta-Analysis of Unplanned Reoperations, Emergency Department Visits and Hospital Readmission After Thyroidectomy. Thyroid. 2018 05; 28(5):624-638. PMID: 29587583.
      View in: PubMed
    49. Margolick J, Wiseman SM. Risk of major complications following thyroidectomy and parathyroidectomy: Utility of the NSQIP surgical risk calculator. Am J Surg. 2018 05; 215(5):936-941. PMID: 29370884.
      View in: PubMed
    50. Joseph Margolick, S. Morad Hameed, Emilie Joos. Canadian Journal of Surgery. An Analysis of Collaboration and Sustainability in Global Surgery. 2017; 4(Supp)(60):S134.
    51. Margolick J, Kanters D, Cameron BH. Procedural skills training for Canadian medical students participating in international electives. Can Med Educ J. 2015; 6(1):e23-33. PMID: 26451227.
      View in: PubMed
    52. Taylor S, Margolick J, Abughosh Z, Goldenberg SL, Lange D, Bowie WR, Bell R, Roscoe D, Machan L, Black P. Ciprofloxacin resistance in the faecal carriage of patients undergoing transrectal ultrasound guided prostate biopsy. BJU Int. 2013 May; 111(6):946-53. PMID: 23464844.
      View in: PubMed
    53. Abughosh Z, Margolick J, Goldenberg SL, Taylor SA, Afshar K, Bell R, Lange D, Bowie WR, Roscoe D, Machan L, Black PC. A prospective randomized trial of povidone-iodine prophylactic cleansing of the rectum before transrectal ultrasound guided prostate biopsy. J Urol. 2013 Apr; 189(4):1326-31. PMID: 23041343.
      View in: PubMed
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