 Brain-Derived Neurotrophic Factor
"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019208
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| MeSH Number(s) |
D12.644.276.860.100 D12.776.467.860.100 D12.776.641.600.100 D23.529.850.100
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| Concept/Terms |
Brain-Derived Neurotrophic Factor- Brain-Derived Neurotrophic Factor
- Brain Derived Neurotrophic Factor
- Factor, Brain-Derived Neurotrophic
- Neurotrophic Factor, Brain-Derived
- BDNF
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Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in UAMS Profiles by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 1 | 1 | 2 | | 2022 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2016 | 3 | 0 | 3 | | 2015 | 0 | 1 | 1 | | 2014 | 0 | 2 | 2 | | 2013 | 1 | 3 | 4 | | 2012 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 |
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Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles over the past ten years.
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Tam TH, Zhang W, Tu Y, Hicks JL, Farcas S, Kim D, Salter MW. Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females. Cell Rep. 2024 Jun 25; 43(6):114293.
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Mercado L, Rose S, Escalona-Vargas D, Siegel ER, Whittington JR, Preissl H, Helmich M, Eswaran H. Correlation of fetal heart rate dynamics to inflammatory markers and brain-derived neurotrophic factor during pregnancy. J Perinat Med. 2024 May 27; 52(4):399-405.
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Tu Y, Muley MM, Beggs S, Salter MW. Microglia-independent peripheral neuropathic pain in male and female mice. Pain. 2022 11 01; 163(11):e1129-e1144.
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Alshehri S, Imam SS. Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects. Biomolecules. 2021 11 23; 11(12).
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Crombie KM, Sartin-Tarm A, Sellnow K, Ahrenholtz R, Lee S, Matalamaki M, Almassi NE, Hillard CJ, Koltyn KF, Adams TG, Cisler JM. Exercise-induced increases in Anandamide and BDNF during extinction consolidation contribute to reduced threat following reinstatement: Preliminary evidence from a randomized controlled trial. Psychoneuroendocrinology. 2021 10; 132:105355.
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Peretti D, Smith HL, Verity N, Humoud I, de Weerd L, Swinden DP, Hayes J, Mallucci GR. TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection. Life Sci Alliance. 2021 04; 4(4).
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Mapplebeck JCS, Lorenzo LE, Lee KY, Gauthier C, Muley MM, De Koninck Y, Prescott SA, Salter MW. Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes. Cell Rep. 2019 07 16; 28(3):590-596.e4.
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Massaro AN, Wu YW, Bammler TK, Comstock B, Mathur A, McKinstry RC, Chang T, Mayock DE, Mulkey SB, Van Meurs K, Juul S. Plasma Biomarkers of Brain Injury in Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr. 2018 03; 194:67-75.e1.
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Hayes JP, Reagan A, Logue MW, Hayes SM, Sadeh N, Miller DR, Verfaellie M, Wolf EJ, McGlinchey RE, Milberg WP, Stone A, Schichman SA, Miller MW. BDNF genotype is associated with hippocampal volume in mild traumatic brain injury. Genes Brain Behav. 2018 02; 17(2):107-117.
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Phillips C. Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection. Neural Plast. 2017; 2017:7260130.
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Zhang Y, Jiao G, Song C, Gu S, Brown RE, Zhang J, Zhang P, Gagnon J, Locke S, Stefanova R, Pelletier C, Zhang Y, Lu H. An Extract from Shrimp Processing By-Products Protects SH-SY5Y Cells from Neurotoxicity Induced by A?25-35. Mar Drugs. 2017 Mar 22; 15(3).
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Strasburger SE, Bhimani PM, Kaabe JH, Krysiak JT, Nanchanatt DL, Nguyen TN, Pough KA, Prince TA, Ramsey NS, Savsani KH, Scandlen L, Cavaretta MJ, Raffa RB. What is the mechanism of Ketamine's rapid-onset antidepressant effect? A concise overview of the surprisingly large number of possibilities. J Clin Pharm Ther. 2017 Apr; 42(2):147-154.
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Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing. Cell Rep. 2016 12 06; 17(10):2753-2765.
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Church DD, Hoffman JR, Mangine GT, Jajtner AR, Townsend JR, Beyer KS, Wang R, La Monica MB, Fukuda DH, Stout JR. Comparison of high-intensity vs. high-volume resistance training on the BDNF response to exercise. J Appl Physiol (1985). 2016 07 01; 121(1):123-8.
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Fouda AY, Alhusban A, Ishrat T, Pillai B, Eldahshan W, Waller JL, Ergul A, Fagan SC. Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke. Mol Neurobiol. 2017 01; 54(1):661-670.
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Alhusban A, Fouda AY, Ishrat T, Soliman S, Fagan SC. Compound 21 is pro-angiogenic in the brain and results in sustained recovery after ischemic stroke. J Hypertens. 2015 Jan; 33(1):170-80.
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Kim W, Noh H, Lee Y, Jeon J, Shanmugavadivu A, McPhie DL, Kim KS, Cohen BM, Seo H, Sonntag KC. MiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons. Mol Neurobiol. 2016 Jan; 53(1):95-108.
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