Succinate-Semialdehyde Dehydrogenase
"Succinate-Semialdehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).
| Descriptor ID |
D050644
|
| MeSH Number(s) |
D08.811.682.657.163.843
|
| Concept/Terms |
Succinate-Semialdehyde Dehydrogenase- Succinate-Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate-Semialdehyde
- Succinate Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate Semialdehyde
- Semialdehyde Dehydrogenase, Succinate
- Succinic Semialdehyde Dehydrogenase
- Dehydrogenase, Succinic Semialdehyde
- Semialdehyde Dehydrogenase, Succinic
- NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
|
Below are MeSH descriptors whose meaning is more general than "Succinate-Semialdehyde Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate-Semialdehyde Dehydrogenase".
This graph shows the total number of publications written about "Succinate-Semialdehyde Dehydrogenase" by people in UAMS Profiles by year, and whether "Succinate-Semialdehyde Dehydrogenase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Succinate-Semialdehyde Dehydrogenase" by people in Profiles over the past ten years.
-
Frye RE. Succinic semialdehyde dehydrogenase deficiency: A model of neurocircuit imbalances in autism and potential insight into new biomarkers. Dev Med Child Neurol. 2023 12; 65(12):1544-1545.
-
Yu D, Tolleson WH, Knox B, Jin Y, Guo L, Guo Y, Kadlubar SA, Ning B. Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells. Biochem Pharmacol. 2015 Dec 15; 98(4):671-80.