 STAT6 Transcription Factor
"STAT6 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-4. Stat6 has been shown to partner with NF-KAPPA B and CCAAT-ENHANCER-BINDING PROTEINS to regulate GENETIC TRANSCRIPTION of interleukin-4 responsive GENES.
| Descriptor ID |
D050800
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| MeSH Number(s) |
D12.644.360.024.342.600 D12.776.157.057.186.600 D12.776.476.024.421.600 D12.776.930.840.600
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| Concept/Terms |
STAT6 Transcription Factor- STAT6 Transcription Factor
- Transcription Factor, STAT6
- STAT6 Protein
- Signal Transducer and Activator of Transcription 6
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Below are MeSH descriptors whose meaning is more general than "STAT6 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT6 Transcription Factor".
This graph shows the total number of publications written about "STAT6 Transcription Factor" by people in UAMS Profiles by year, and whether "STAT6 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "STAT6 Transcription Factor" by people in Profiles over the past ten years.
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Park Y, Jung J, Jeong S, van Ee A, Garza LA, Jang M, Kim D, Park J. Reversine enhances skin barrier functions by suppressing the IL-4- and IL-13-mediated STAT6 pathway. J Dermatol Sci. 2023 08; 111(2):71-73.
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Bakhshwin A, Berry RS, Cox RM, Li R, Reynolds JP, Rubin BP, McKenney JK. Malignant solitary fibrous tumour of the prostate: four cases emphasising significant histological and immunophenotypical overlap with sarcomatoid carcinoma. Pathology. 2020 Oct; 52(6):643-648.
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Cox RM, Chan E, Sangoi AR, Zou Y, McKenney JK. STAT6 monoclonal antibody is highly specific for the distinction between solitary fibrous tumour and prostatic stromal proliferations. Histopathology. 2020 03; 76(4):625-626.
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Rahal OM, Wolfe AR, Mandal PK, Larson R, Tin S, Jimenez C, Zhang D, Horton J, Reuben JM, McMurray JS, Woodward WA. Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer. Int J Radiat Oncol Biol Phys. 2018 03 15; 100(4):1034-1043.
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Bao L, Alexander JB, Shi VY, Mohan GC, Chan LS. Interleukin-4 up-regulation of epidermal interleukin-19 expression in keratinocytes involves the binding of signal transducer and activator of transcription 6 (Stat6) to the imperfect Stat6 sites. Immunology. 2014 Dec; 143(4):601-8.
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