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Immunoglobulin Class Switching

"Immunoglobulin Class Switching" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.


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This graph shows the total number of publications written about "Immunoglobulin Class Switching" by people in UAMS Profiles by year, and whether "Immunoglobulin Class Switching" was a major or minor topic of these publications.
Bar chart showing 7 publications over 6 distinct years, with a maximum of 2 publications in 2011
To see the data from this visualization as text, click here.
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