 DNA Polymerase II
"DNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7.
| Descriptor ID |
D004257
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| MeSH Number(s) |
D08.811.913.696.445.308.300.230
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| Concept/Terms |
DNA Polymerase II- DNA Polymerase II
- Polymerase II, DNA
- Pol II
- DNA Polymerase epsilon
- Polymerase epsilon, DNA
- DNA-Dependent DNA Polymerase II
- DNA Dependent DNA Polymerase II
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Below are MeSH descriptors whose meaning is more general than "DNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase II".
This graph shows the total number of publications written about "DNA Polymerase II" by people in UAMS Profiles by year, and whether "DNA Polymerase II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2011 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Polymerase II" by people in Profiles over the past ten years.
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Baniak N, Fadare O, K?bel M, DeCoteau J, Parkash V, Hecht JL, Hanley KZ, Gwin K, Zheng W, Quick CM, Jarboe EA, Liang SX, Kinloch M. Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are Uncommon. Am J Surg Pathol. 2019 04; 43(4):531-537.
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Logan CV, Murray JE, Parry DA, Robertson A, Bellelli R, Tarnauskaite ?, Challis R, Cleal L, Borel V, Fluteau A, Santoyo-Lopez J, Aitman T, Barroso I, Basel D, Bicknell LS, Goel H, Hu H, Huff C, Hutchison M, Joyce C, Knox R, Lacroix AE, Langlois S, McCandless S, McCarrier J, Metcalfe KA, Morrissey R, Murphy N, Netchine I, O'Connell SM, Olney AH, Paria N, Rosenfeld JA, Sherlock M, Syverson E, White PC, Wise C, Yu Y, Zacharin M, Banerjee I, Reijns M, Bober MB, Semple RK, Boulton SJ, Rios JJ, Jackson AP. DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency. Am J Hum Genet. 2018 12 06; 103(6):1038-1044.
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Garc?a-Rodr?guez LJ, De Piccoli G, Marchesi V, Jones RC, Edmondson RD, Labib K. A conserved Pol? binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1. Nucleic Acids Res. 2015 Oct 15; 43(18):8830-8.
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Eddy S, Maddukuri L, Ketkar A, Zafar MK, Henninger EE, Pursell ZF, Eoff RL. Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA. Biochemistry. 2015 May 26; 54(20):3218-30.
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