 Enzyme-Linked Immunosorbent Assay
"Enzyme-Linked Immunosorbent Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
| Descriptor ID |
D004797
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| MeSH Number(s) |
E05.478.566.350.170 E05.478.566.380.360 E05.478.583.400.170 E05.601.495.350.170 E05.601.495.380.360
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| Concept/Terms |
Enzyme-Linked Immunosorbent Assay- Enzyme-Linked Immunosorbent Assay
- Assay, Enzyme-Linked Immunosorbent
- Assays, Enzyme-Linked Immunosorbent
- Enzyme Linked Immunosorbent Assay
- Enzyme-Linked Immunosorbent Assays
- Immunosorbent Assay, Enzyme-Linked
- Immunosorbent Assays, Enzyme-Linked
- ELISA
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Below are MeSH descriptors whose meaning is more general than "Enzyme-Linked Immunosorbent Assay".
Below are MeSH descriptors whose meaning is more specific than "Enzyme-Linked Immunosorbent Assay".
This graph shows the total number of publications written about "Enzyme-Linked Immunosorbent Assay" by people in UAMS Profiles by year, and whether "Enzyme-Linked Immunosorbent Assay" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2025 | 0 | 1 | 1 | | 2021 | 0 | 5 | 5 | | 2020 | 0 | 3 | 3 | | 2019 | 0 | 1 | 1 | | 2018 | 1 | 2 | 3 | | 2017 | 0 | 2 | 2 | | 2016 | 0 | 8 | 8 | | 2015 | 3 | 6 | 9 | | 2014 | 0 | 4 | 4 | | 2013 | 1 | 5 | 6 | | 2012 | 0 | 14 | 14 | | 2011 | 1 | 10 | 11 | | 2010 | 2 | 12 | 14 | | 2009 | 0 | 6 | 6 | | 2008 | 0 | 5 | 5 | | 2007 | 1 | 18 | 19 | | 2006 | 0 | 7 | 7 | | 2005 | 1 | 20 | 21 | | 2004 | 0 | 11 | 11 | | 2003 | 0 | 8 | 8 | | 2001 | 0 | 5 | 5 | | 2000 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1997 | 0 | 4 | 4 | | 1995 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 |
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Below are the most recent publications written about "Enzyme-Linked Immunosorbent Assay" by people in Profiles over the past ten years.
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Surico PL, Naderi A, Singh RB, Kahale F, Farsi Y, Lee S, Musayeva A, Chen Y, Dana R. Antagonizing NK-1R modulates pain perception following corneal injury. Exp Eye Res. 2025 Feb; 251:110230.
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Mourtakos S, Kavouras S, Vasiliou S, Soultanakis H, Bardis C, Sidossis L, Tenta R. Bone Mineral Content Distribution in Response to Long-term Training of Elite Rowers. In Vivo. 2023 Mar-Apr; 37(2):611-617.
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Page AE, Partridge E, Erol E, Scoggin KE, Fedorka CE, Ruby RE, Ball BA, Horohov DW, Adam E. Development and Use of an Enzyme-Linked Immunosorbent Assay to Determine Temporal Exposure Patterns to Putative Agents of Nocardioform Placentitis. J Equine Vet Sci. 2022 02; 109:103826.
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Gray WL, Wichman G, Das A, Traina-Dorge V. An enzyme-linked immunosorbent assay (ELISA) to determine Simian Varicella Virus antibody titers in infected rhesus monkeys (Macaca mulatta). J Med Primatol. 2022 02; 51(1):20-26.
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Wang Z, Muecksch F, Schaefer-Babajew D, Finkin S, Viant C, Gaebler C, Hoffmann HH, Barnes CO, Cipolla M, Ramos V, Oliveira TY, Cho A, Schmidt F, Da Silva J, Bednarski E, Aguado L, Yee J, Daga M, Turroja M, Millard KG, Jankovic M, Gazumyan A, Zhao Z, Rice CM, Bieniasz PD, Caskey M, Hatziioannou T, Nussenzweig MC. Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection. Nature. 2021 07; 595(7867):426-431.
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Cohen AA, Gnanapragasam PNP, Lee YE, Hoffman PR, Ou S, Kakutani LM, Keeffe JR, Wu HJ, Howarth M, West AP, Barnes CO, Nussenzweig MC, Bjorkman PJ. Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice. Science. 2021 02 12; 371(6530):735-741.
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Ferris RL, Stacy N, Stein AB, Chiles H, Goe A. COMPARISON OF FECAL CYTOLOGY AND PRESENCE OF CLOSTRIDIUM PERFRINGENS ENTEROTOXIN IN CAPTIVE BLACK-FOOTED FERRETS (MUSTELA NIGRIPES) BASED ON DIET AND FECAL QUALITY. J Zoo Wildl Med. 2021 Jan; 51(4):814-824.
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Lumley SF, Eyre DW, McNaughton AL, Howarth A, Hoosdally S, Hatch SB, Kavanagh J, Chau KK, Downs LO, Cox S, Dunn L, Justice A, Wareing S, Dingle K, Rudkin J, Auckland K, Fyfe A, Bolton J, Paton R, Mentzer AJ, Jeffery K, Andersson MI, James T, Peto TEA, Marsden BD, Screaton G, Cornall RJ, Klenerman P, Ebner D, Stuart DI, Crook DW, Stoesser N, Kennedy SH, Thompson C, Gupta S, Matthews PC. SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020. Euro Surveill. 2020 10; 25(42).
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Robbiani DF, Gaebler C, Muecksch F, Lorenzi JCC, Wang Z, Cho A, Agudelo M, Barnes CO, Gazumyan A, Finkin S, H?ggl?f T, Oliveira TY, Viant C, Hurley A, Hoffmann HH, Millard KG, Kost RG, Cipolla M, Gordon K, Bianchini F, Chen ST, Ramos V, Patel R, Dizon J, Shimeliovich I, Mendoza P, Hartweger H, Nogueira L, Pack M, Horowitz J, Schmidt F, Weisblum Y, Michailidis E, Ashbrook AW, Waltari E, Pak JE, Huey-Tubman KE, Koranda N, Hoffman PR, West AP, Rice CM, Hatziioannou T, Bjorkman PJ, Bieniasz PD, Caskey M, Nussenzweig MC. Convergent antibody responses to SARS-CoV-2 in convalescent individuals. Nature. 2020 08; 584(7821):437-442.
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Zhang L, Pang R, Xue X, Bao J, Ye S, Dai Y, Zheng Y, Fu Q, Hu Z, Yi Y. Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19. Aging (Albany NY). 2020 Apr 22; 12(8):6536-6542.
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Peng H, Chang Y, Baker RC, Zhang G. Interference of mycotoxin binders with ELISA, HPLC and LC-MS/MS analysis of aflatoxins in maize and maize gluten. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2020 Mar; 37(3):496-506.
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Eko Mba JM, Bisseye C, Mombo LE, Ntsame Ndong JM, Mbina Ekayeng SC, Bengone C, M'batchi B, Nagalo BM. Assessment of rapid diagnostic tests and fourth-generation Enzyme-Linked Immunosorbent Assays in the screening of Human Immunodeficiency and Hepatitis B virus infections among first-time blood donors in Libreville (Gabon). J Clin Lab Anal. 2019 Mar; 33(3):e22824.
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Quera R, Moreno M, Simian D, Ib??ez P, Lubascher J, Figueroa C, Flores L, Kronberg U, Pizarro G, Flux? D. [Usefulness of therapeutic monitoring of infliximab in the treatment of inflammatory bowel disease]. Rev Med Chil. 2018 Nov; 146(11):1241-1251.
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Mudambi S, Pera P, Washington D, Remenyik E, Fidrus E, Shafirstein G, Bellnier D, Paragh G. Photodynamic therapy does not induce cyclobutane pyrimidine dimers in the presence of melanin. Photodiagnosis Photodyn Ther. 2018 Jun; 22:241-244.
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Jarvis IWH, Enlo-Scott Z, Nagy E, Mudway IS, Tetley TD, Arlt VM, Phillips DH. Genotoxicity of fine and coarse fraction ambient particulate matter in immortalised normal (TT1) and cancer-derived (A549) alveolar epithelial cells. Environ Mol Mutagen. 2018 05; 59(4):290-301.
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Bakshi RK, Gupta K, Jordan SJ, Brown LT, Press CG, Gorwitz RJ, Papp JR, Morrison SG, Lee JY, Morrison RP, Geisler WM. Immunoglobulin-Based Investigation of Spontaneous Resolution of Chlamydia trachomatis Infection. J Infect Dis. 2017 06 01; 215(11):1653-1656.
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Danda D, Sharma R, Truong D, Koelsch KA, Kurien BT, Bagavant H, Deshmukh U, Kaufman CE, Lewis DM, Stone DU, Radfar L, Rasmussen A, Sivils KL, Scofield RH. Anti-La positive, anti-Ro negative subset of primary Sj?gren's syndrome: anti-La is a reality but is the disease? Clin Exp Rheumatol. 2017 May-Jun; 35(3):438-444.
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Farris RA, Price ET. Reverse Translational Study of Fenofibrate's Observed Effects in Diabetes-Associated Retinopathy. Clin Transl Sci. 2017 03; 10(2):110-116.
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Ye S, Fujiwara T, Zhou J, Varughese KI, Zhao H. LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42. Int J Biol Sci. 2016; 12(12):1488-1499.
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Gao Y, Cao Z, Yang X, Abdelmegeed MA, Sun J, Chen S, Beger RD, Davis K, Salminen WF, Song BJ, Mendrick DL, Yu LR. Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury. Proteomics Clin Appl. 2017 01; 11(1-2).
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Atluri K, Lee J, Seabold D, Elangovan S, Salem AK. Gene-Activated Titanium Surfaces Promote In Vitro Osteogenesis. Int J Oral Maxillofac Implants. 2017 Mar/Apr; 32(2):e83?e96.
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Girotra M, Garg S, Anand R, Song Y, Dutta SK. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in the Elderly: Long-Term Outcomes and Microbiota Changes. Dig Dis Sci. 2016 10; 61(10):3007-3015.
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Janhsen WK, Arnold C, Hentschel J, Lehmann T, Pfister W, Baier M, B?er K, H?nniger K, Kurzai O, Hipler UC, Mainz JG. Colonization of CF patients' upper airways with S. aureus contributes more decisively to upper airway inflammation than P. aeruginosa. Med Microbiol Immunol. 2016 Oct; 205(5):485-500.
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Goyal S, Lyzogubov VV, Ali O, Bora PS, Bora NS, Uwaydat SH. Effect of aspirin on models of retinal pigment epithelium pathology. Clin Exp Ophthalmol. 2016 Sep; 44(7):610-617.
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Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, Wang J, Nie W, Smith G, Hensley LE, Olinger GG, Kuhn JH, Holbrook MR, Johnson RF, Perlman S, Sullivan E, Frieman MB. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Sci Transl Med. 2016 Feb 17; 8(326):326ra21.
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Wang W, Bodles-Brakhop AM, Barger SW. A Role for P-Glycoprotein in Clearance of Alzheimer Amyloid ? -Peptide from the Brain. Curr Alzheimer Res. 2016; 13(6):615-20.
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Huang L, Beiting DP, Gebreselassie NG, Gagliardo LF, Ruyechan MC, Lee NA, Lee JJ, Appleton JA. Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury. PLoS Pathog. 2015 Dec; 11(12):e1005347.
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Wikenheiser DJ, Ghosh D, Kennedy B, Stumhofer JS. The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection. J Immunol. 2016 Jan 15; 196(2):778-91.
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Pandey S, Drobena G, Cottler-Fox M. TRANSFUSION MEDICINE ILLUSTRATED. Heparin-induced thrombocytopenia: a cautionary tale. Transfusion. 2015 Dec; 55(12):2790.
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Dai L, Trillo-Tinoco J, Cao Y, Bonstaff K, Doyle L, Del Valle L, Whitby D, Parsons C, Reiss K, Zabaleta J, Qin Z. Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma. Blood. 2015 Dec 24; 126(26):2821-31.
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Koskenpato K, Ainola M, Przybyla B, Kouri VP, Virkki L, Koskenpato J, Ristim?ki A, Konttinen YT. Diminished salivary epidermal growth factor secretion: a link between Sj?gren's syndrome and autoimmune gastritis? Scand J Rheumatol. 2016; 45(2):118-21.
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Janech MG, Rodgers JL, Arthur JM, Velez JC. Letter to the editor: "Concern regarding quantification of urinary nephrin by a commercially available ELISA". Am J Physiol Renal Physiol. 2015 Aug 01; 309(3):F269-70.
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Sullivan JC, Imig JD. Reply to "Letter to the editor: 'Concern regarding quantification of urinary nephrin by commercially available ELISA'". Am J Physiol Renal Physiol. 2015 Aug 01; 309(3):F271.
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